Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 189499014

GI number: 189499014

Start: 17725

End: 19047

Strand: Direct

Name: surA [H]

Synonym: Cphamn1_0014

Alternate gene names: 189499014

Gene position: 17725-19047 (Clockwise)

Preceding gene: 189499013

Following gene: 189499019

Centisome position: 0.65

GC content: 48.0

Gene sequence:

>1323_bases
ATGATTATGAAAAATCGTTTTTTAAGGTTAGTCGCTGTTGTTTTTATTATGGTTGCCGCCGGGTTTCAACGTGCCGGTGC
GGCAGTTGCCGACAGAATTGTTGCTGTTGTCGGTAACGAAATGATTATGCAGTCACAGGTTGATGAGCAGGCTATGATGG
CCCGTCTTCAGTATACGGAGGCCAAAAATGACCCGTCGCTGAAAGCAGGTATTCTCGAGAACCTCGTTACCAGAAAAATC
GTGCTGACCAAGGCCAGGATTGACAGTATTCAGGTTGATGAGTCCGATATCGAGAAGAGAACTGATGAAAGAATGAGGTT
CCTTCGATCCAAATTCAGCTCTATTGAGGAGATGGAATCTACCTTTTCAAAGTCATATGCGGTAATCGAAAAGGAGATCA
AAGACGATATACGTGATCAGCAGTTGATCAACAACCTCCGGAGACAGAAAATGATGGGGGTGAACGTCACCTATGAGGAG
GTTGAGGACTTCTATGGTGCAAACCGCGATAAACTTCCGGTTGTGCCTGAGGCTGTTGAGGTTTCCCAGGTCGTGATGTA
TCCGAAGGTTACTGCTGAAGCGAAAGCAAAGGCACGCGCAGCCATTGAAGCAATGCAGCAGAGGTTGAGATCAGGAGAGA
ATTTCGCTGCTCTTGCCAGAGAGTATTCCCAGGATCCCGGATCTGCCCGTCTCGGCGGAGATCTCGGTTATTCCCGGCGT
GGGGAATTTGTAAAGAATTACGAGAAGGTTGCATTCGGGCTTGAAGAAGGTGAGATCTCCGGGATTGTTGAAACACGTTT
TGGCTACCATATCATCCAGCTTCTGGATAAGGAGCAGGACGCGGTGCACACGCGGCATATTCTGATTGTTTTCGACAGAA
GTACTCTCGATGCTCCGGCGGCAAAGGCTGCCCTTGAAATGATCCGCAGTGATATCATCAGCGGAAAATCTGACTTTGCT
GAAATGGCCAGAGAGTATTCAGACGATCCTGTATCGTCCAAGTACGGAGGAGTGATCCGTAACACTGAAACCGGCGAGAC
CAGATTTGCCGTTTCATCGCTTCGTGATCAGCTTAAAACCGTTGTCAGATCATTTAAAAAGGTTGGTGATATCAGCAGCG
TCGTGCGGGTGGCTCCTGAATCAGGCGCGCCGTTCTATGCGATTTTTAAGCTGAACAGCAGGGAGCCTGCACATAAACTC
GATTTGTCTTCGGATTATGCCAGGCTCGAAAAACTTGCCATTGACGAGAAGCAGAACAGATTGTTCCAGGAATGGATCAA
TGAGCTGCAGAAAGAGGTCTATGTCAGGATCTCAGACATCTAA

Upstream 100 bases:

>100_bases
TATTGTTGAGAAACAAAAACAGTATTATAGTACAGTGCTTGAAAAGGCAAGGAAAAAGTTTCAGTAATCTGTACTGAATC
GCATAACGTGGTAAAGCTGA

Downstream 100 bases:

>100_bases
ACGTCTGACATAGCGGGCGTTTTTTTCAATAAAGTTTCGGCGTGGTTCGACCTTGTCCCCCATAAGTGTCGAAAAGACCT
GATCGGCTTCCATGGCATTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIMKNRFLRLVAVVFIMVAAGFQRAGAAVADRIVAVVGNEMIMQSQVDEQAMMARLQYTEAKNDPSLKAGILENLVTRKI
VLTKARIDSIQVDESDIEKRTDERMRFLRSKFSSIEEMESTFSKSYAVIEKEIKDDIRDQQLINNLRRQKMMGVNVTYEE
VEDFYGANRDKLPVVPEAVEVSQVVMYPKVTAEAKAKARAAIEAMQQRLRSGENFAALAREYSQDPGSARLGGDLGYSRR
GEFVKNYEKVAFGLEEGEISGIVETRFGYHIIQLLDKEQDAVHTRHILIVFDRSTLDAPAAKAALEMIRSDIISGKSDFA
EMAREYSDDPVSSKYGGVIRNTETGETRFAVSSLRDQLKTVVRSFKKVGDISSVVRVAPESGAPFYAIFKLNSREPAHKL
DLSSDYARLEKLAIDEKQNRLFQEWINELQKEVYVRISDI

Sequences:

>Translated_440_residues
MIMKNRFLRLVAVVFIMVAAGFQRAGAAVADRIVAVVGNEMIMQSQVDEQAMMARLQYTEAKNDPSLKAGILENLVTRKI
VLTKARIDSIQVDESDIEKRTDERMRFLRSKFSSIEEMESTFSKSYAVIEKEIKDDIRDQQLINNLRRQKMMGVNVTYEE
VEDFYGANRDKLPVVPEAVEVSQVVMYPKVTAEAKAKARAAIEAMQQRLRSGENFAALAREYSQDPGSARLGGDLGYSRR
GEFVKNYEKVAFGLEEGEISGIVETRFGYHIIQLLDKEQDAVHTRHILIVFDRSTLDAPAAKAALEMIRSDIISGKSDFA
EMAREYSDDPVSSKYGGVIRNTETGETRFAVSSLRDQLKTVVRSFKKVGDISSVVRVAPESGAPFYAIFKLNSREPAHKL
DLSSDYARLEKLAIDEKQNRLFQEWINELQKEVYVRISDI
>Mature_440_residues
MIMKNRFLRLVAVVFIMVAAGFQRAGAAVADRIVAVVGNEMIMQSQVDEQAMMARLQYTEAKNDPSLKAGILENLVTRKI
VLTKARIDSIQVDESDIEKRTDERMRFLRSKFSSIEEMESTFSKSYAVIEKEIKDDIRDQQLINNLRRQKMMGVNVTYEE
VEDFYGANRDKLPVVPEAVEVSQVVMYPKVTAEAKAKARAAIEAMQQRLRSGENFAALAREYSQDPGSARLGGDLGYSRR
GEFVKNYEKVAFGLEEGEISGIVETRFGYHIIQLLDKEQDAVHTRHILIVFDRSTLDAPAAKAALEMIRSDIISGKSDFA
EMAREYSDDPVSSKYGGVIRNTETGETRFAVSSLRDQLKTVVRSFKKVGDISSVVRVAPESGAPFYAIFKLNSREPAHKL
DLSSDYARLEKLAIDEKQNRLFQEWINELQKEVYVRISDI

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=366, Percent_Identity=27.8688524590164, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49754; Mature: 49754

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00153 ATPASE_GAMMA ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIMKNRFLRLVAVVFIMVAAGFQRAGAAVADRIVAVVGNEMIMQSQVDEQAMMARLQYTE
CCCHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKNDPSLKAGILENLVTRKIVLTKARIDSIQVDESDIEKRTDERMRFLRSKFSSIEEMES
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFSKSYAVIEKEIKDDIRDQQLINNLRRQKMMGVNVTYEEVEDFYGANRDKLPVVPEAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHH
VSQVVMYPKVTAEAKAKARAAIEAMQQRLRSGENFAALAREYSQDPGSARLGGDLGYSRR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
GEFVKNYEKVAFGLEEGEISGIVETRFGYHIIQLLDKEQDAVHTRHILIVFDRSTLDAPA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEEEECCCCCCHH
AKAALEMIRSDIISGKSDFAEMAREYSDDPVSSKYGGVIRNTETGETRFAVSSLRDQLKT
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCCCEECCCCCCHHHHHHHHHHHHHH
VVRSFKKVGDISSVVRVAPESGAPFYAIFKLNSREPAHKLDLSSDYARLEKLAIDEKQNR
HHHHHHHHCCHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHH
LFQEWINELQKEVYVRISDI
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA