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The map label for this gene is aldH [H]

Identifier: 189353875

GI number: 189353875

Start: 2181382

End: 2182959

Strand: Reverse

Name: aldH [H]

Synonym: BMULJ_05127

Alternate gene names: 189353875

Gene position: 2182959-2181382 (Counterclockwise)

Preceding gene: 189353878

Following gene: 189353873

Centisome position: 88.27

GC content: 71.99

Gene sequence:

>1578_bases
ATGCAACTGACAGGAGAGATGCTGATCGGCGCCGACGCGGTGGTCGGCTCGGCCGGCACCTTGTACGCATTCGACCCGTC
GAAGGGCGCGCCGATCGATGTGCCGGCCTTCGGCATCGCGACGCAGGCCGACGTCGATCGCGCGTGCGAACTCGCGCGCG
GCGCGTTCGACGCCTATCGCGCGCAGCCGCTCCCGGTGCGCGCGTCGTTTCTCGAGGCGATCGCCGACGAGATCGTCGCG
CTCGGCGACGCGCTGATCGAGCGCGCGCACGCGGAAACGGGCCTGCCCGCCGCGCGGCTGCAGGGCGAACGCGCGCGCAC
CGTCGGCCAGCTTCGTCTGTTTGCGCGCGTCGTGCGCGACGGCCGGTTTCTCGCCGCGTCGATCGATCCCGCGCAGCCGA
CGCGCACGCCGCTGCCGCGCTCGGACCTGCGGCTGCAGAAGATTCCGCTCGGCCCCGTCGCGGTGTTCGGTGCGAGCAAT
TTCCCGCTCGCGTTTTCGGTCGCGGGCGGCGACACCGCCTCGGCGCTGGCGGCCGGCTGCCCGGTGATCGTGAAGGGGCA
CGAGGCGCACCTCGGCACGTCGGAGCTCGTCGGGCGCGCGATCCGCGCGGCGGTCGAGAAGTGCGGGATGCCGGCCGGCG
TGTTTTCGCTGCTGGTCGGGCCGGGCCGCGTGGTCGGCACGGCGCTCGTCAACCATCCGGCGATTCAGGCGGTCGGCTTC
ACCGGCTCGCGGCAGGGCGGCATGGCGCTCGTGCAGCTGGCGAACGCGCGGCCGCAGCCGATTCCCGTCTACGCGGAAAT
GAGCAGCATCAACCCCGTCGTGCTGTTCCCCGCGGCGCTCGCCGCACGCGGCGACGCGATCGCGACGGGCTTCGTCGAAT
CGCTGACGCTCGGCGTCGGCCAGTTCTGTACGAACCCGGGCCTCGTGCTCGCGATCGACGGCCCCGAGCTCGACCGCTTC
GAGGCGGTCGCCGCGCAGGCGCTCGCGAAGAAACCGGCCGGCGTGATGCTGACGCGCGGCATCGCGGACGCGTATCGCAA
CGGCCGCGGCACGCTCGCCGAACTGCCGGGCGTGCGCGAGATCGGCGCCGGCGAGCCGGCGCAGACCGAATGCCAGGCCG
GCGGCGCGCTGTACGATGTCGCCGCGCAGGCATTCCTGTCCGAGCCGGCGTTCGGTCACGAGGTGTTCGGGCCGTCGTCG
CTGATCGTGCGTTGCCGCGACTTCGACGAGGTCGCGCGCGTGCTCGATGCGCTCGAAGGCCAGCTTACGGCGACGCTGCA
GATGGATGCCGACGACAAGCCGCTCGCGCGCCGGCTGCTGCCGATCCTCGAACGCAAGGCCGGTCGTCTGCTCGTGAACG
GTTTTCCGACCGGCGTCGAGGTGTGCGACGCGATGGTGCACGGCGGCCCGTTCCCGGCGACGTCGAACGCGGCGTTCACG
TCGGTCGGCGCGACCGCGATCGACCGGTTCCTGCGGCCGGTGTGCTATCAGGACTTCCCGGACGATCTGTTGCCCGAAGC
GCTGCAGCAGGACAATCCGCTTTCGATTCCGCGGCTGCGGGACGGGAAGGCGGAGTGA

Upstream 100 bases:

>100_bases
AGGCCGGCTTCGGACGACAAGGAAAGCGCGCCGGCGTCGGCAGACATCGTATCTGTTGCGCTACAATGTTCGATCCCACC
CGAACCCACGGAGCACACCC

Downstream 100 bases:

>100_bases
TGGGCTGAACGCGTCGTTTCGGCGGGCGGTCGGCCGCCGGGATGACGACGGGAAATGACGAGGCGGAATCGGCCCGGTGG
TCGGTTCCGCTTTTTTATCG

Product: NAD-dependent aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MQLTGEMLIGADAVVGSAGTLYAFDPSKGAPIDVPAFGIATQADVDRACELARGAFDAYRAQPLPVRASFLEAIADEIVA
LGDALIERAHAETGLPAARLQGERARTVGQLRLFARVVRDGRFLAASIDPAQPTRTPLPRSDLRLQKIPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKGHEAHLGTSELVGRAIRAAVEKCGMPAGVFSLLVGPGRVVGTALVNHPAIQAVGF
TGSRQGGMALVQLANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVESLTLGVGQFCTNPGLVLAIDGPELDRF
EAVAAQALAKKPAGVMLTRGIADAYRNGRGTLAELPGVREIGAGEPAQTECQAGGALYDVAAQAFLSEPAFGHEVFGPSS
LIVRCRDFDEVARVLDALEGQLTATLQMDADDKPLARRLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAAFT
SVGATAIDRFLRPVCYQDFPDDLLPEALQQDNPLSIPRLRDGKAE

Sequences:

>Translated_525_residues
MQLTGEMLIGADAVVGSAGTLYAFDPSKGAPIDVPAFGIATQADVDRACELARGAFDAYRAQPLPVRASFLEAIADEIVA
LGDALIERAHAETGLPAARLQGERARTVGQLRLFARVVRDGRFLAASIDPAQPTRTPLPRSDLRLQKIPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKGHEAHLGTSELVGRAIRAAVEKCGMPAGVFSLLVGPGRVVGTALVNHPAIQAVGF
TGSRQGGMALVQLANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVESLTLGVGQFCTNPGLVLAIDGPELDRF
EAVAAQALAKKPAGVMLTRGIADAYRNGRGTLAELPGVREIGAGEPAQTECQAGGALYDVAAQAFLSEPAFGHEVFGPSS
LIVRCRDFDEVARVLDALEGQLTATLQMDADDKPLARRLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAAFT
SVGATAIDRFLRPVCYQDFPDDLLPEALQQDNPLSIPRLRDGKAE
>Mature_525_residues
MQLTGEMLIGADAVVGSAGTLYAFDPSKGAPIDVPAFGIATQADVDRACELARGAFDAYRAQPLPVRASFLEAIADEIVA
LGDALIERAHAETGLPAARLQGERARTVGQLRLFARVVRDGRFLAASIDPAQPTRTPLPRSDLRLQKIPLGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVIVKGHEAHLGTSELVGRAIRAAVEKCGMPAGVFSLLVGPGRVVGTALVNHPAIQAVGF
TGSRQGGMALVQLANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVESLTLGVGQFCTNPGLVLAIDGPELDRF
EAVAAQALAKKPAGVMLTRGIADAYRNGRGTLAELPGVREIGAGEPAQTECQAGGALYDVAAQAFLSEPAFGHEVFGPSS
LIVRCRDFDEVARVLDALEGQLTATLQMDADDKPLARRLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAAFT
SVGATAIDRFLRPVCYQDFPDDLLPEALQQDNPLSIPRLRDGKAE

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=397, Percent_Identity=25.4408060453401, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI153266822, Length=435, Percent_Identity=25.5172413793103, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI25952152, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI12007648, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI25777724, Length=391, Percent_Identity=24.2966751918159, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21361176, Length=434, Percent_Identity=23.2718894009217, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87081896, Length=463, Percent_Identity=27.2138228941685, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789015, Length=344, Percent_Identity=28.1976744186047, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788042, Length=317, Percent_Identity=29.0220820189274, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787558, Length=244, Percent_Identity=30.7377049180328, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786504, Length=270, Percent_Identity=27.4074074074074, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787250, Length=162, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI133930964, Length=309, Percent_Identity=27.831715210356, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323822, Length=454, Percent_Identity=26.2114537444934, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323821, Length=289, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54640; Mature: 54640

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTGEMLIGADAVVGSAGTLYAFDPSKGAPIDVPAFGIATQADVDRACELARGAFDAYR
CCCCCCEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AQPLPVRASFLEAIADEIVALGDALIERAHAETGLPAARLQGERARTVGQLRLFARVVRD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHC
GRFLAASIDPAQPTRTPLPRSDLRLQKIPLGPVAVFGASNFPLAFSVAGGDTASALAAGC
CCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCHHHHHHCCC
PVIVKGHEAHLGTSELVGRAIRAAVEKCGMPAGVFSLLVGPGRVVGTALVNHPAIQAVGF
CEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEECC
TGSRQGGMALVQLANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVESLTLGVG
CCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHH
QFCTNPGLVLAIDGPELDRFEAVAAQALAKKPAGVMLTRGIADAYRNGRGTLAELPGVRE
HHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCHHHCCCCHH
IGAGEPAQTECQAGGALYDVAAQAFLSEPAFGHEVFGPSSLIVRCRDFDEVARVLDALEG
CCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCC
QLTATLQMDADDKPLARRLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAAFT
CEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHH
SVGATAIDRFLRPVCYQDFPDDLLPEALQQDNPLSIPRLRDGKAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLTGEMLIGADAVVGSAGTLYAFDPSKGAPIDVPAFGIATQADVDRACELARGAFDAYR
CCCCCCEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AQPLPVRASFLEAIADEIVALGDALIERAHAETGLPAARLQGERARTVGQLRLFARVVRD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHC
GRFLAASIDPAQPTRTPLPRSDLRLQKIPLGPVAVFGASNFPLAFSVAGGDTASALAAGC
CCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCHHHHHHCCC
PVIVKGHEAHLGTSELVGRAIRAAVEKCGMPAGVFSLLVGPGRVVGTALVNHPAIQAVGF
CEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEECC
TGSRQGGMALVQLANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVESLTLGVG
CCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHH
QFCTNPGLVLAIDGPELDRFEAVAAQALAKKPAGVMLTRGIADAYRNGRGTLAELPGVRE
HHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCHHHCCCCHH
IGAGEPAQTECQAGGALYDVAAQAFLSEPAFGHEVFGPSSLIVRCRDFDEVARVLDALEG
CCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCC
QLTATLQMDADDKPLARRLLPILERKAGRLLVNGFPTGVEVCDAMVHGGPFPATSNAAFT
CEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHH
SVGATAIDRFLRPVCYQDFPDDLLPEALQQDNPLSIPRLRDGKAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]