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The map label for this gene is catR [C]

Identifier: 189352336

GI number: 189352336

Start: 386188

End: 387084

Strand: Direct

Name: catR [C]

Synonym: BMULJ_03555

Alternate gene names: 189352336

Gene position: 386188-387084 (Clockwise)

Preceding gene: 189352332

Following gene: 189352338

Centisome position: 15.62

GC content: 70.57

Gene sequence:

>897_bases
ATGGAATTGCGCCAGCTTCGGTACTTCATGGCCGTGGCCGAGGAAATGAACATCACGCGCGCGGCGGAGCGGCTGCACAT
CACGCAGCCGCCGCTCAGTCGCCAGTTGCAGGCGATCGAGGAGGAGCTCGGGCTGCCGCTGTTCGTGCGCGGCGCACGGC
CGCTGAAGTTGACCGACGCGGGGCGCGTGTTCTACGCGCAGGCGCGGCGCGTCGTCGAGCAGGCCGACGAGCTCGGGCCG
CTGACGCGGCGGCTCGCGCAGCTGTCGGAACGGATCGTGATCGGCTTCGTGCCATCGACGCTGTACGGTGCGCTGCCGGA
CGTGATCCGCGCGTTTCGCGAGGCGCAGCCGGACGTCGAGCTGTCGCTCGTCGAAATGTTCACGCTCGAGCAACTGGGCG
CGCTGAAGGGCGGGCGGATCGACGTCGGCTTCGGCCGGCTGCGCTTCGACGACGACCAGCTCGTGCGCGAAGCGCTGATC
GAGGAAAAGCTGATCGCGGCGGTGCCGGTCGGTCATCCGCTCGCCGATCCCGATCGGCCGCTGACGCTCGCGGACCTCGC
GAACGAAACGCTGATCGTCTACCCGAGCACGCCGCGGCCGAGCTTCGCGGATCAGCAGTTGTCCGCGCTGCGCGACGGCG
CCCTGGTGCCGGCCGCCGTGCACGAGGTGCGCGAACTGCAGACGGCGCTCGGGCTCGTCGCGGCGAAGGTCGGCGTGTCG
CTGGTGCCGGAGAGCGTGGAGGGCGTGCGCGTGAAGGGCGTCGTCTACCGGCGGCTGCCGGAACCGGTCGCGACGTCGCC
GATCATCATGAGCCGCCGGCTGCACGGCGAAAGCGCGGCGACCGCGAAGTTCTGCGCGATCGCGCGCGAGATGATCGTGC
CGGCCGGGCATGCGTAG

Upstream 100 bases:

>100_bases
TGCTATCATGCGATTCCTCCTGTCGGTGCACATGGTAGGAATACGCGCCGGGCCGCGTCCAACACTCTTTCCGACTACTT
CCATACCTTCGGAGCATGAA

Downstream 100 bases:

>100_bases
CGGCGGTCGATCGTTCGATCGTTTGCCCGCAGGTTCGCAACTAACGGCCTATCCCGCATGCGTCCGCATGGCGGCGGCGC
CTGAGCGCATGAGATGCATG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORFR1 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MELRQLRYFMAVAEEMNITRAAERLHITQPPLSRQLQAIEEELGLPLFVRGARPLKLTDAGRVFYAQARRVVEQADELGP
LTRRLAQLSERIVIGFVPSTLYGALPDVIRAFREAQPDVELSLVEMFTLEQLGALKGGRIDVGFGRLRFDDDQLVREALI
EEKLIAAVPVGHPLADPDRPLTLADLANETLIVYPSTPRPSFADQQLSALRDGALVPAAVHEVRELQTALGLVAAKVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIIMSRRLHGESAATAKFCAIAREMIVPAGHA

Sequences:

>Translated_298_residues
MELRQLRYFMAVAEEMNITRAAERLHITQPPLSRQLQAIEEELGLPLFVRGARPLKLTDAGRVFYAQARRVVEQADELGP
LTRRLAQLSERIVIGFVPSTLYGALPDVIRAFREAQPDVELSLVEMFTLEQLGALKGGRIDVGFGRLRFDDDQLVREALI
EEKLIAAVPVGHPLADPDRPLTLADLANETLIVYPSTPRPSFADQQLSALRDGALVPAAVHEVRELQTALGLVAAKVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIIMSRRLHGESAATAKFCAIAREMIVPAGHA
>Mature_298_residues
MELRQLRYFMAVAEEMNITRAAERLHITQPPLSRQLQAIEEELGLPLFVRGARPLKLTDAGRVFYAQARRVVEQADELGP
LTRRLAQLSERIVIGFVPSTLYGALPDVIRAFREAQPDVELSLVEMFTLEQLGALKGGRIDVGFGRLRFDDDQLVREALI
EEKLIAAVPVGHPLADPDRPLTLADLANETLIVYPSTPRPSFADQQLSALRDGALVPAAVHEVRELQTALGLVAAKVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIIMSRRLHGESAATAKFCAIAREMIVPAGHA

Specific function: Probable positive regulator of the cat1 operon which encode enzymes responsible for the degradation of catechol to acetyl-CoA via the beta-ketoadipate pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=285, Percent_Identity=36.4912280701754, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788887, Length=290, Percent_Identity=33.448275862069, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI2367136, Length=267, Percent_Identity=29.5880149812734, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=28.6885245901639, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=28.6885245901639, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081904, Length=205, Percent_Identity=33.6585365853659, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=29.020979020979, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787601, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788296, Length=202, Percent_Identity=33.6633663366337, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=28.8973384030418, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790208, Length=288, Percent_Identity=28.4722222222222, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=26.1044176706827, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787530, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789173, Length=194, Percent_Identity=31.9587628865979, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789204, Length=285, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=26.0162601626016, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=189, Percent_Identity=29.1005291005291, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32682; Mature: 32682

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRYFMAVAEEMNITRAAERLHITQPPLSRQLQAIEEELGLPLFVRGARPLKLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEECCC
GRVFYAQARRVVEQADELGPLTRRLAQLSERIVIGFVPSTLYGALPDVIRAFREAQPDVE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCH
LSLVEMFTLEQLGALKGGRIDVGFGRLRFDDDQLVREALIEEKLIAAVPVGHPLADPDRP
HHHHHHHHHHHHHCCCCCEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LTLADLANETLIVYPSTPRPSFADQQLSALRDGALVPAAVHEVRELQTALGLVAAKVGVS
EEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPESVEGVRVKGVVYRRLPEPVATSPIIMSRRLHGESAATAKFCAIAREMIVPAGHA
HCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELRQLRYFMAVAEEMNITRAAERLHITQPPLSRQLQAIEEELGLPLFVRGARPLKLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEECCC
GRVFYAQARRVVEQADELGPLTRRLAQLSERIVIGFVPSTLYGALPDVIRAFREAQPDVE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCH
LSLVEMFTLEQLGALKGGRIDVGFGRLRFDDDQLVREALIEEKLIAAVPVGHPLADPDRP
HHHHHHHHHHHHHCCCCCEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LTLADLANETLIVYPSTPRPSFADQQLSALRDGALVPAAVHEVRELQTALGLVAAKVGVS
EEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPESVEGVRVKGVVYRRLPEPVATSPIIMSRRLHGESAATAKFCAIAREMIVPAGHA
HCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9473520 [H]