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The map label for this gene is fadH [H]

Identifier: 189352329

GI number: 189352329

Start: 379178

End: 381211

Strand: Direct

Name: fadH [H]

Synonym: BMULJ_03548

Alternate gene names: 189352329

Gene position: 379178-381211 (Clockwise)

Preceding gene: 189352326

Following gene: 189352332

Centisome position: 15.33

GC content: 68.68

Gene sequence:

>2034_bases
ATGACGACACCTTTCCCGCATCTGCTCGCACCGCTCGATCTCGGCTTCACGACGCTGAAGAACCGTGTACTGATGGGTTC
GATGCATACGGGCCTCGAAGACAGCCGCAAGACGCTGCCGCGGCTCGCGGACTATTTCGCGGAGCGGGCGCGCGGCGGCG
TCGGGCTGATCGTGACGGGCGGCTTCGCGCCGAACGTGGCCGGCTGGACCAAGCCGTTCGGCGGCACGCTGATGACGTCG
GCCGCCGCGCGGCGCCATCGCGCGATCACGCGCGCGGTCCACGCGGAGGACGGCAAGATCGCGCTGCAGATCCTGCATAC
GGGCCGTTACGGCTATCACCCGTTCGCGGTTGCGCCGTCGAAGATCAAGTCGCCGATCTCGCCGTTCGCGCCGCACGAGC
TGAGCGCCCGCGGCATCGAGCGACAGATCCGCGCGTTCGTCCGCTGCGCGCAGCTCGCGCGCGAAGCCGGCTACGACGGC
GTCGAGATCATGGGTTCCGAAGGCTACCTGATCAATCAGTTCATCTCGATGCATACGAACAAGCGCACCGACGCGTGGGG
CGGCGCTTACGAAAACCGGATCCGGCTGCCGATCGAGATCGTCGAGCGCACGCGCGAAGCGGTCGGCCGCGATTTCATCC
TGATCTACCGGCTGTCGATGCTCGACCTGATTCCGGACGGCAGCGACTGGCGCGAGACCGTGCAGCTCGCGAAGGCGGTC
GAGCGCGCGGGCGCGACGATTCTCAATACGGGAATCGGCTGGCACGAGGCGCGCGTGCCGACGATCGCGACGTCGGTGCC
GCGCGGCGCGTTCGCATGGGTCACGCAGAAGATGAAGGGCGAGGTCGGCATTCCGCTCGTCACGACGAACCGCATCAATC
GGCCCGAAATCGCCGAACGGATTCTCGCCGACGGCTGCGCGGACATGGTGTCGATGGCGCGCCCGCTGCTCGCGGATCCG
GAATTCGTCGTCAAGGCGGCGCAGGGCCGCGCGGACGAGATCAACACGTGCATCGGCTGCAATCAGGCCTGTCTCGATCA
TGCGTTCAAGAACCGGATCGCATCGTGCCTGATGAATCCGCGCGCGTGTCACGAGACCGAGCTGCAGTATGCGCGCGCCG
CGCAGCCGAAGCGCATCGCGGTGGTCGGCGCCGGGCCGGCCGGGCTCGCCTGCGCGACCGTGCTCGCGCAGCGCGGCCAT
CGCGTCGACCTGTTCGACGGCGCGGCGGAAATCGGCGGCCAGTTCAATCTCGCGAAACGGATTCCGGGCAAGGAAGAGTT
TCACGAAGCGCTGCGCTATTTCGGTCGCCAGATCGAGCTGACCGGCGTCGCGCTGCATCTGAACCGGCGCGTCGAGGCGA
GCGACCTGATCGCCGGCGGCTACGACGAGATCGTGCTCGCGACCGGCGTATCGCCGCGCGATCCGAAGATTCCGGGGCAG
GACGGGCCGAACGTACTCGGCTATATCGACGTGCTGACGGGCGCGCGGCCGGTCGGCCCGCGTGTCGCGGTGATCGGTGC
GGGCGGGATCGGCTTCGACGTCGCGGAATTTCTCGTGCAGGACGGACCGTCGCCGGCGCTCGATCTCGACGAATGGAAAG
CGGAGTGGGGTGTGACCGACCCGGCCGCGACGCGCGGCGGCATCACGCGCGCCAAGGTGTCGCCGCCGGCGCGCGACGTG
ACGCTGTTGCAGCGCAAGCCTGCGCCGCTCGGCAAGGGGCTCGGCAAGACGACCGGCTGGATCCACCGCGCGACGCTGAA
GATGAAGCAGGTGAAGATGATCGGCGGCGTGAACTACGAACGGATCGATGCGCGCGGGTTGCACGTGTCGTACGGCGAGC
AGCGCACCGGGCACGCGCTGATCGAAGCCGACACGATCGTGCTCTGCACCGGCCAGGAACCGCAGCGCGCGCTGCTCGCG
CCGCTGCAGGCGGCCGGGCGTTCGGTGCACGTGATCGGCGGCGCGGACCGCGCAGCCGAACTCGATGCAAAGCGCGCGAT
CGACCAGGGCGCGCGGCTCGCCGCGCGGCTCTAA

Upstream 100 bases:

>100_bases
GATATTGGCCGGAAATGACAAGCATTATGGCTGTTTGTCCCCTCACGTTCAACGCGGCGCGCGCCTACGATGACGCTCAT
CGCGTATCGCTCCGACCATC

Downstream 100 bases:

>100_bases
GGCCGGCTCGCGCTTCGCGCGCTCACGCCGCTTCGGCCTGCTCCGCCGCTTCCGCTTCGAGCATCGCGCGGACGATCAGA
TAGACGGCCGGCAGATCGTC

Product: NADPH2-dependent 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MTTPFPHLLAPLDLGFTTLKNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNVAGWTKPFGGTLMTS
AAARRHRAITRAVHAEDGKIALQILHTGRYGYHPFAVAPSKIKSPISPFAPHELSARGIERQIRAFVRCAQLAREAGYDG
VEIMGSEGYLINQFISMHTNKRTDAWGGAYENRIRLPIEIVERTREAVGRDFILIYRLSMLDLIPDGSDWRETVQLAKAV
ERAGATILNTGIGWHEARVPTIATSVPRGAFAWVTQKMKGEVGIPLVTTNRINRPEIAERILADGCADMVSMARPLLADP
EFVVKAAQGRADEINTCIGCNQACLDHAFKNRIASCLMNPRACHETELQYARAAQPKRIAVVGAGPAGLACATVLAQRGH
RVDLFDGAAEIGGQFNLAKRIPGKEEFHEALRYFGRQIELTGVALHLNRRVEASDLIAGGYDEIVLATGVSPRDPKIPGQ
DGPNVLGYIDVLTGARPVGPRVAVIGAGGIGFDVAEFLVQDGPSPALDLDEWKAEWGVTDPAATRGGITRAKVSPPARDV
TLLQRKPAPLGKGLGKTTGWIHRATLKMKQVKMIGGVNYERIDARGLHVSYGEQRTGHALIEADTIVLCTGQEPQRALLA
PLQAAGRSVHVIGGADRAAELDAKRAIDQGARLAARL

Sequences:

>Translated_677_residues
MTTPFPHLLAPLDLGFTTLKNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNVAGWTKPFGGTLMTS
AAARRHRAITRAVHAEDGKIALQILHTGRYGYHPFAVAPSKIKSPISPFAPHELSARGIERQIRAFVRCAQLAREAGYDG
VEIMGSEGYLINQFISMHTNKRTDAWGGAYENRIRLPIEIVERTREAVGRDFILIYRLSMLDLIPDGSDWRETVQLAKAV
ERAGATILNTGIGWHEARVPTIATSVPRGAFAWVTQKMKGEVGIPLVTTNRINRPEIAERILADGCADMVSMARPLLADP
EFVVKAAQGRADEINTCIGCNQACLDHAFKNRIASCLMNPRACHETELQYARAAQPKRIAVVGAGPAGLACATVLAQRGH
RVDLFDGAAEIGGQFNLAKRIPGKEEFHEALRYFGRQIELTGVALHLNRRVEASDLIAGGYDEIVLATGVSPRDPKIPGQ
DGPNVLGYIDVLTGARPVGPRVAVIGAGGIGFDVAEFLVQDGPSPALDLDEWKAEWGVTDPAATRGGITRAKVSPPARDV
TLLQRKPAPLGKGLGKTTGWIHRATLKMKQVKMIGGVNYERIDARGLHVSYGEQRTGHALIEADTIVLCTGQEPQRALLA
PLQAAGRSVHVIGGADRAAELDAKRAIDQGARLAARL
>Mature_676_residues
TTPFPHLLAPLDLGFTTLKNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNVAGWTKPFGGTLMTSA
AARRHRAITRAVHAEDGKIALQILHTGRYGYHPFAVAPSKIKSPISPFAPHELSARGIERQIRAFVRCAQLAREAGYDGV
EIMGSEGYLINQFISMHTNKRTDAWGGAYENRIRLPIEIVERTREAVGRDFILIYRLSMLDLIPDGSDWRETVQLAKAVE
RAGATILNTGIGWHEARVPTIATSVPRGAFAWVTQKMKGEVGIPLVTTNRINRPEIAERILADGCADMVSMARPLLADPE
FVVKAAQGRADEINTCIGCNQACLDHAFKNRIASCLMNPRACHETELQYARAAQPKRIAVVGAGPAGLACATVLAQRGHR
VDLFDGAAEIGGQFNLAKRIPGKEEFHEALRYFGRQIELTGVALHLNRRVEASDLIAGGYDEIVLATGVSPRDPKIPGQD
GPNVLGYIDVLTGARPVGPRVAVIGAGGIGFDVAEFLVQDGPSPALDLDEWKAEWGVTDPAATRGGITRAKVSPPARDVT
LLQRKPAPLGKGLGKTTGWIHRATLKMKQVKMIGGVNYERIDARGLHVSYGEQRTGHALIEADTIVLCTGQEPQRALLAP
LQAAGRSVHVIGGADRAAELDAKRAIDQGARLAARL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=676, Percent_Identity=59.6153846153846, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=344, Percent_Identity=28.1976744186047, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=180, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=324, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564188, Length=322, Percent_Identity=23.6024844720497, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=250, Percent_Identity=25.6, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559802, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17566914, Length=312, Percent_Identity=25.3205128205128, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72001454, Length=113, Percent_Identity=32.7433628318584, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321973, Length=227, Percent_Identity=27.3127753303965, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=224, Percent_Identity=27.2321428571429, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73036; Mature: 72905

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPFPHLLAPLDLGFTTLKNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTG
CCCCCCHHHHHHHCCHHHHHCEEEECHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
GFAPNVAGWTKPFGGTLMTSAAARRHRAITRAVHAEDGKIALQILHTGRYGYHPFAVAPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECHH
KIKSPISPFAPHELSARGIERQIRAFVRCAQLAREAGYDGVEIMGSEGYLINQFISMHTN
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
KRTDAWGGAYENRIRLPIEIVERTREAVGRDFILIYRLSMLDLIPDGSDWRETVQLAKAV
CCCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHH
ERAGATILNTGIGWHEARVPTIATSVPRGAFAWVTQKMKGEVGIPLVTTNRINRPEIAER
HHCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
ILADGCADMVSMARPLLADPEFVVKAAQGRADEINTCIGCNQACLDHAFKNRIASCLMNP
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
RACHETELQYARAAQPKRIAVVGAGPAGLACATVLAQRGHRVDLFDGAAEIGGQFNLAKR
CCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHCCCEEHHHC
IPGKEEFHEALRYFGRQIELTGVALHLNRRVEASDLIAGGYDEIVLATGVSPRDPKIPGQ
CCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCC
DGPNVLGYIDVLTGARPVGPRVAVIGAGGIGFDVAEFLVQDGPSPALDLDEWKAEWGVTD
CCCCCEEHEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
PAATRGGITRAKVSPPARDVTLLQRKPAPLGKGLGKTTGWIHRATLKMKQVKMIGGVNYE
CCHHCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
RIDARGLHVSYGEQRTGHALIEADTIVLCTGQEPQRALLAPLQAAGRSVHVIGGADRAAE
EECCCCCEEECCCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHH
LDAKRAIDQGARLAARL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPFPHLLAPLDLGFTTLKNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTG
CCCCCHHHHHHHCCHHHHHCEEEECHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
GFAPNVAGWTKPFGGTLMTSAAARRHRAITRAVHAEDGKIALQILHTGRYGYHPFAVAPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECHH
KIKSPISPFAPHELSARGIERQIRAFVRCAQLAREAGYDGVEIMGSEGYLINQFISMHTN
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
KRTDAWGGAYENRIRLPIEIVERTREAVGRDFILIYRLSMLDLIPDGSDWRETVQLAKAV
CCCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHH
ERAGATILNTGIGWHEARVPTIATSVPRGAFAWVTQKMKGEVGIPLVTTNRINRPEIAER
HHCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
ILADGCADMVSMARPLLADPEFVVKAAQGRADEINTCIGCNQACLDHAFKNRIASCLMNP
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
RACHETELQYARAAQPKRIAVVGAGPAGLACATVLAQRGHRVDLFDGAAEIGGQFNLAKR
CCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHCCCEEHHHC
IPGKEEFHEALRYFGRQIELTGVALHLNRRVEASDLIAGGYDEIVLATGVSPRDPKIPGQ
CCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCC
DGPNVLGYIDVLTGARPVGPRVAVIGAGGIGFDVAEFLVQDGPSPALDLDEWKAEWGVTD
CCCCCEEHEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
PAATRGGITRAKVSPPARDVTLLQRKPAPLGKGLGKTTGWIHRATLKMKQVKMIGGVNYE
CCHHCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
RIDARGLHVSYGEQRTGHALIEADTIVLCTGQEPQRALLAPLQAAGRSVHVIGGADRAAE
EECCCCCEEECCCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHH
LDAKRAIDQGARLAARL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]