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The map label for this gene is ttuB [H]

Identifier: 189352273

GI number: 189352273

Start: 318758

End: 320068

Strand: Direct

Name: ttuB [H]

Synonym: BMULJ_03492

Alternate gene names: 189352273

Gene position: 318758-320068 (Clockwise)

Preceding gene: 189352272

Following gene: 189352274

Centisome position: 12.89

GC content: 67.43

Gene sequence:

>1311_bases
ATGCAAGCGGATCCGGAAACCCGCGTCGCGCGGAAACTGATGTGGCGGATCATTCCGTTCGTGATGCTGCTGTATTTCGT
CAGCTTTCTCGATCGCGTCAACGTCGGCTTTGCCGCGATGACGATGAACAAGGCGATCGGCCTGTCGCCCACTGCGTTCG
GGCTCGGCGGCGGGCTGTTCTTCATCGGCTACTTCCTGTTCGAGGTGCCGTCGAACCTGATTCTTCACCGGGTCGGCGCG
CGGATCTGGATCGCGCGCGTGATGATCACGTGGGGCATCGTGTCGGCCGTGTCCGCGTTCGCGGTCGGACCGACGAGCTT
CTACGTACTGCGCTTCCTGCTCGGCGTGGCGGAGGCCGGCTTTTTCCCCGGCATCATCCTGTACCTGAGCCTGTGGTTTC
CGGCGCGGCAGCGCGCGGTGGCCGCCGCGTGGTTCATGGCGGCCGCGCCGATCTCGACTGCGATCGGCTCGCCGCTATCC
GGAGCCATCATGCAGATGCCGCCGATGTTCGGCCTCGCGGACTGGCAGATGCTGTACATCGTCGAGGCATTGCCGGCGAT
CGTGCTCGGCTTCGTCGTGCTGAAGTGCCTGATCGATACGCCATCGAAGGCCGCGTGGCTGCAGCCGGACGAGCGCGACT
GGCTGATCGCGAAGCTGAAGTCCGAAGCCGACGCGCGGCATGGGCGCAGCGGCCATACGGCCGGCGCGTGGCAGGCGCTG
CGCGACCCGCGCGTGCTCGCGCTCGCACTGATCTACTTCGGCACGTCGGCGGGGCTCTATACGCTCGGCTTGTGGGCGCC
GCTGATGGTGAAGCAGTTCGGCTTCAGCGCGCTGCAGACAGGCCTGCTGACCGGCATTCCGAGCGTCGCGGCGGTCGTCG
CGATGATCGTGTGGGCGCGTCATTCGGACCGCACCGGCGAGCGCACGTGGCACGTCGTGATTCCGTGCGTGCTGGCGTGC
ATCGGCTTCGTGTTCGCCGGCGAAGCGAGCACTGCGCTGCTGACGGTGCTCGCGCTGGTCGTCGTCAACGTCGGGATCAG
CGCCGCGAAGGCGCCGCTGTGGGCGATGCCGAGCGCGTTCCTGTCGGGCGCAGGTGCAGCCGCGGGGATCGCGATGATCA
ACTCGATCGGCAATCTCGGCGGCTTCGTCGGCCCGTTCGCGATCGGCTGGCTGAAGCAGGCGACGGGCGGCTATGCGGCG
GGGCTCTACGTCGTGGCGGCGACGCTCGCGGTATCGGCGATCGTCACGCTGATGCTGAGCCGCAAGGGTGCGCGCGAGCA
GGTCGCGTCACGCGTGCAGCACCATCACTGA

Upstream 100 bases:

>100_bases
TACGACTCGCGCAACCGACGCGAGCGGGGCGCCGATCCGCACCGCGGATCGGCCGGCATTCCTATCACAGAGCACGGCTC
GACCTCGAAGGAGGAGACAC

Downstream 100 bases:

>100_bases
ATGCGGCGGGCGATGTCGGCTGCGCATGCGGCGGCCGATGCGGTCGACGTGTCGATGAAGCAGTCGCTGAACGCGCGCGA
CGCATAGCCTTCGCGGTACA

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MQADPETRVARKLMWRIIPFVMLLYFVSFLDRVNVGFAAMTMNKAIGLSPTAFGLGGGLFFIGYFLFEVPSNLILHRVGA
RIWIARVMITWGIVSAVSAFAVGPTSFYVLRFLLGVAEAGFFPGIILYLSLWFPARQRAVAAAWFMAAAPISTAIGSPLS
GAIMQMPPMFGLADWQMLYIVEALPAIVLGFVVLKCLIDTPSKAAWLQPDERDWLIAKLKSEADARHGRSGHTAGAWQAL
RDPRVLALALIYFGTSAGLYTLGLWAPLMVKQFGFSALQTGLLTGIPSVAAVVAMIVWARHSDRTGERTWHVVIPCVLAC
IGFVFAGEASTALLTVLALVVVNVGISAAKAPLWAMPSAFLSGAGAAAGIAMINSIGNLGGFVGPFAIGWLKQATGGYAA
GLYVVAATLAVSAIVTLMLSRKGAREQVASRVQHHH

Sequences:

>Translated_436_residues
MQADPETRVARKLMWRIIPFVMLLYFVSFLDRVNVGFAAMTMNKAIGLSPTAFGLGGGLFFIGYFLFEVPSNLILHRVGA
RIWIARVMITWGIVSAVSAFAVGPTSFYVLRFLLGVAEAGFFPGIILYLSLWFPARQRAVAAAWFMAAAPISTAIGSPLS
GAIMQMPPMFGLADWQMLYIVEALPAIVLGFVVLKCLIDTPSKAAWLQPDERDWLIAKLKSEADARHGRSGHTAGAWQAL
RDPRVLALALIYFGTSAGLYTLGLWAPLMVKQFGFSALQTGLLTGIPSVAAVVAMIVWARHSDRTGERTWHVVIPCVLAC
IGFVFAGEASTALLTVLALVVVNVGISAAKAPLWAMPSAFLSGAGAAAGIAMINSIGNLGGFVGPFAIGWLKQATGGYAA
GLYVVAATLAVSAIVTLMLSRKGAREQVASRVQHHH
>Mature_436_residues
MQADPETRVARKLMWRIIPFVMLLYFVSFLDRVNVGFAAMTMNKAIGLSPTAFGLGGGLFFIGYFLFEVPSNLILHRVGA
RIWIARVMITWGIVSAVSAFAVGPTSFYVLRFLLGVAEAGFFPGIILYLSLWFPARQRAVAAAWFMAAAPISTAIGSPLS
GAIMQMPPMFGLADWQMLYIVEALPAIVLGFVVLKCLIDTPSKAAWLQPDERDWLIAKLKSEADARHGRSGHTAGAWQAL
RDPRVLALALIYFGTSAGLYTLGLWAPLMVKQFGFSALQTGLLTGIPSVAAVVAMIVWARHSDRTGERTWHVVIPCVLAC
IGFVFAGEASTALLTVLALVVVNVGISAAKAPLWAMPSAFLSGAGAAAGIAMINSIGNLGGFVGPFAIGWLKQATGGYAA
GLYVVAATLAVSAIVTLMLSRKGAREQVASRVQHHH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=396, Percent_Identity=21.2121212121212, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082071, Length=434, Percent_Identity=37.0967741935484, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1789152, Length=446, Percent_Identity=25.1121076233184, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=22.7906976744186, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=22.8699551569507, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367379, Length=440, Percent_Identity=23.4090909090909, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367193, Length=291, Percent_Identity=23.7113402061856, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=320, Percent_Identity=26.875, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322025, Length=191, Percent_Identity=26.7015706806283, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322612, Length=306, Percent_Identity=26.1437908496732, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324410, Length=168, Percent_Identity=25, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=311, Percent_Identity=22.508038585209, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=324, Percent_Identity=22.5308641975309, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46552; Mature: 46552

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHCCC
>Mature Secondary Structure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CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]