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The map label for this gene is nahR [H]

Identifier: 189352224

GI number: 189352224

Start: 263220

End: 264140

Strand: Direct

Name: nahR [H]

Synonym: BMULJ_03442

Alternate gene names: 189352224

Gene position: 263220-264140 (Clockwise)

Preceding gene: 189352223

Following gene: 189352225

Centisome position: 10.64

GC content: 67.32

Gene sequence:

>921_bases
ATGAACAAGTCCCATCCGGTCGTCACCGATCTCAATCTGCTGCGCGTGTTCCTCGCGATCTCGGAACTGCGCAGCCTGAC
CGCGGCCGGCGAACGGCTCGGGCTGACGCAGCCGGCCGTCAGTCACGCGCTGCGGCGGCTGCGCAATCTGTTCGACGATC
CGTTGTTCGTGCGCACGCCGGCCGGCATGGCGCCGACCGATGCCGCGCGCCAATTGCACGGGCCGCTGACGCGCGCGTTC
GACATCATCGATCTCGCCGTGCAGCAGGTCGCGCATTTCGATCCGGCCACCGCGAATCGCGTGTTCCGCATTTCGATGTC
GGACATGTCGGAGTTCTACTTCCTGCCGCCGCTGCTCGCAAAGCTCGCGGAAGTCGCGCCGGGCGTGCGCGTGGAGGTCG
CGAGCGCCGCTGTGGAAGCGGTCGGCGCCGCGATGCGCAGCGGCGAGATCGATCTCGCGCTCGGCTATGTGCCGGATCCG
GGCCCCGGCTGCGTGAGCGAGCCGCTGTTTACGGACGAGCACGTGTGCATGGTGCGTGCCGGGCATCCGCTGCGCAAGCG
CACGCCGACGCAGGCCGACCTGGCGGCGCTGCGCTACATCTACGCGAGCAGCAATGCGACCGGACACCGGATGGTCGAAA
CCTGGCTCGACGAGCTACAGGTCGAACGCACGATCGTGCTGCGCCTGCCGCATTTCATCGTTGCGCCGGAGATCGTCCAG
CATACCGATCTCGCGATCATCTTTCCGCGCAGCGTCGCGGAGCGCTTCAACCGCGGCCGCGCATTCCGGATCCTGCCGTT
GCCGTTCGTGCTGCCGCCGATCGAAATCGACCTGCACACGCATGCGCAGTTTTCGTCGGATCCCGGTATCGCGTGGCTGC
GCGCGCTGATCGTCGAGATGTTCCGCCGCCCGGTCGCGTAA

Upstream 100 bases:

>100_bases
AGCCCGCGCGCTGCGCGGCGCCGGCCGTCCGCGGTGACCTGCGCGCGACCCGGCGCCCGGCGCGCGGCGTCGCGCATCCT
ACCGGCGGTTCACGAGCGCC

Downstream 100 bases:

>100_bases
CCGCGCGCCGCGCGCCGGCCGCCCAAGTGTCCGTCGTCACATCCGCTTCACTGATTTAGAATGCGTTCACGCATCAATTT
GACGAATAGCGGAGGGTGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNKSHPVVTDLNLLRVFLAISELRSLTAAGERLGLTQPAVSHALRRLRNLFDDPLFVRTPAGMAPTDAARQLHGPLTRAF
DIIDLAVQQVAHFDPATANRVFRISMSDMSEFYFLPPLLAKLAEVAPGVRVEVASAAVEAVGAAMRSGEIDLALGYVPDP
GPGCVSEPLFTDEHVCMVRAGHPLRKRTPTQADLAALRYIYASSNATGHRMVETWLDELQVERTIVLRLPHFIVAPEIVQ
HTDLAIIFPRSVAERFNRGRAFRILPLPFVLPPIEIDLHTHAQFSSDPGIAWLRALIVEMFRRPVA

Sequences:

>Translated_306_residues
MNKSHPVVTDLNLLRVFLAISELRSLTAAGERLGLTQPAVSHALRRLRNLFDDPLFVRTPAGMAPTDAARQLHGPLTRAF
DIIDLAVQQVAHFDPATANRVFRISMSDMSEFYFLPPLLAKLAEVAPGVRVEVASAAVEAVGAAMRSGEIDLALGYVPDP
GPGCVSEPLFTDEHVCMVRAGHPLRKRTPTQADLAALRYIYASSNATGHRMVETWLDELQVERTIVLRLPHFIVAPEIVQ
HTDLAIIFPRSVAERFNRGRAFRILPLPFVLPPIEIDLHTHAQFSSDPGIAWLRALIVEMFRRPVA
>Mature_306_residues
MNKSHPVVTDLNLLRVFLAISELRSLTAAGERLGLTQPAVSHALRRLRNLFDDPLFVRTPAGMAPTDAARQLHGPLTRAF
DIIDLAVQQVAHFDPATANRVFRISMSDMSEFYFLPPLLAKLAEVAPGVRVEVASAAVEAVGAAMRSGEIDLALGYVPDP
GPGCVSEPLFTDEHVCMVRAGHPLRKRTPTQADLAALRYIYASSNATGHRMVETWLDELQVERTIVLRLPHFIVAPEIVQ
HTDLAIIFPRSVAERFNRGRAFRILPLPFVLPPIEIDLHTHAQFSSDPGIAWLRALIVEMFRRPVA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=296, Percent_Identity=28.0405405405405, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=27.4834437086093, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786820, Length=272, Percent_Identity=25, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI157672245, Length=257, Percent_Identity=23.3463035019455, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=28.4916201117318, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081766, Length=275, Percent_Identity=24.3636363636364, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=229, Percent_Identity=26.6375545851528, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=263, Percent_Identity=23.9543726235741, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33849; Mature: 33849

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSHPVVTDLNLLRVFLAISELRSLTAAGERLGLTQPAVSHALRRLRNLFDDPLFVRTP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECC
AGMAPTDAARQLHGPLTRAFDIIDLAVQQVAHFDPATANRVFRISMSDMSEFYFLPPLLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
KLAEVAPGVRVEVASAAVEAVGAAMRSGEIDLALGYVPDPGPGCVSEPLFTDEHVCMVRA
HHHHHCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
GHPLRKRTPTQADLAALRYIYASSNATGHRMVETWLDELQVERTIVLRLPHFIVAPEIVQ
CCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHCHHHHH
HTDLAIIFPRSVAERFNRGRAFRILPLPFVLPPIEIDLHTHAQFSSDPGIAWLRALIVEM
HCCEEEEECHHHHHHHCCCCEEEEECCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHH
FRRPVA
HHCCCC
>Mature Secondary Structure
MNKSHPVVTDLNLLRVFLAISELRSLTAAGERLGLTQPAVSHALRRLRNLFDDPLFVRTP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECC
AGMAPTDAARQLHGPLTRAFDIIDLAVQQVAHFDPATANRVFRISMSDMSEFYFLPPLLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
KLAEVAPGVRVEVASAAVEAVGAAMRSGEIDLALGYVPDPGPGCVSEPLFTDEHVCMVRA
HHHHHCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
GHPLRKRTPTQADLAALRYIYASSNATGHRMVETWLDELQVERTIVLRLPHFIVAPEIVQ
CCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHCHHHHH
HTDLAIIFPRSVAERFNRGRAFRILPLPFVLPPIEIDLHTHAQFSSDPGIAWLRALIVEM
HCCEEEEECHHHHHHHCCCCEEEEECCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHH
FRRPVA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]