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The map label for this gene is nahR [H]

Identifier: 189352225

GI number: 189352225

Start: 264240

End: 265160

Strand: Direct

Name: nahR [H]

Synonym: BMULJ_03443

Alternate gene names: 189352225

Gene position: 264240-265160 (Clockwise)

Preceding gene: 189352224

Following gene: 189352228

Centisome position: 10.68

GC content: 68.3

Gene sequence:

>921_bases
ATGACGTCGGTCGATCATCTCGATCTGAACCTGCTGCGGGTGTTCCAGGCGATCGTCGAGGAACGCAGCCTGACGAAGGC
CGGCGAGCGGCTCGCGCTGTCGCAGCCGGCCGTCAGCTATTCGCTCGGACGGCTGCGCACGCTGTTCGACGATCCGCTGT
TCGTGCGCACGCGCGCGGGCATGCAGCCGACACCCGTCGCACTCGAACTCGCGGGCATCGTCGGCAAGGCGCTCGACATG
GTGCGCGTCGCGCTGCGCTATGCGGAGCGCTTCGATCCGGCGACGAGTACGCGCACGTTCCGGCTGTCGCTGTCGGATGC
CGGCGAGATGGCCTATCTGCCCGCGATCTGCCGCGCACTGCGCGAGCGCGCGCCGCGCGTGACGCTCAGCGTGCAGCCAA
TGCCGGTCGAGGCGATCGAGGAAGCGCTGCGCGCGAGCCGGCTCGATTTCGCGATCGGCAATCTGCCGGAGCTGATGCCG
CGCACGCGCCATCAGCTGCTGTTCGAGGAAACCTATGTCTGCATGACGGGCCGTCGGCGCGGATTGCCGAGCGGCACGAC
GCTGACGCTCGAGCAGTTCGTGCGGGCCGCGCACGTCAACGTGAAGTCGGTCGAGCACAGCCATCACGCGCTCGACGACG
CGCTGCGCGCGCAGGGCGTCGGCCGCAATGTCGCGCTCGAAGTGCCGCACTTCGTCGCACTGCCCGGCGTGCTGCAGGTA
ACGGACTTGTATGCCACGCTGCCGAAGCGGCTCGCGCAGATCCTGAATCGCGACAACGCGTTCCGGCTCTACGCGCTGCC
CGTGCCGCTGCCGCCCGCGCCGGTGACGATGCACTGGCACGAGCATTTCCACGAGGACGAAGGCATTACGTGGATGCGTG
CGCTGCTTGCGGAGATCGTCGAGCGTTTCGACGGCGCGTGA

Upstream 100 bases:

>100_bases
ACCGCGCGCCGCGCGCCGGCCGCCCAAGTGTCCGTCGTCACATCCGCTTCACTGATTTAGAATGCGTTCACGCATCAATT
TGACGAATAGCGGAGGGTGC

Downstream 100 bases:

>100_bases
CGCGCTCGCGGCCGCGCGCCGTTTATAGATCGAGCACGAGCACCGGCGAACGCGCGCGCGACACGCAGCAGCAGATCACC
GAATTGCTCGCGCGTTCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTSVDHLDLNLLRVFQAIVEERSLTKAGERLALSQPAVSYSLGRLRTLFDDPLFVRTRAGMQPTPVALELAGIVGKALDM
VRVALRYAERFDPATSTRTFRLSLSDAGEMAYLPAICRALRERAPRVTLSVQPMPVEAIEEALRASRLDFAIGNLPELMP
RTRHQLLFEETYVCMTGRRRGLPSGTTLTLEQFVRAAHVNVKSVEHSHHALDDALRAQGVGRNVALEVPHFVALPGVLQV
TDLYATLPKRLAQILNRDNAFRLYALPVPLPPAPVTMHWHEHFHEDEGITWMRALLAEIVERFDGA

Sequences:

>Translated_306_residues
MTSVDHLDLNLLRVFQAIVEERSLTKAGERLALSQPAVSYSLGRLRTLFDDPLFVRTRAGMQPTPVALELAGIVGKALDM
VRVALRYAERFDPATSTRTFRLSLSDAGEMAYLPAICRALRERAPRVTLSVQPMPVEAIEEALRASRLDFAIGNLPELMP
RTRHQLLFEETYVCMTGRRRGLPSGTTLTLEQFVRAAHVNVKSVEHSHHALDDALRAQGVGRNVALEVPHFVALPGVLQV
TDLYATLPKRLAQILNRDNAFRLYALPVPLPPAPVTMHWHEHFHEDEGITWMRALLAEIVERFDGA
>Mature_305_residues
TSVDHLDLNLLRVFQAIVEERSLTKAGERLALSQPAVSYSLGRLRTLFDDPLFVRTRAGMQPTPVALELAGIVGKALDMV
RVALRYAERFDPATSTRTFRLSLSDAGEMAYLPAICRALRERAPRVTLSVQPMPVEAIEEALRASRLDFAIGNLPELMPR
TRHQLLFEETYVCMTGRRRGLPSGTTLTLEQFVRAAHVNVKSVEHSHHALDDALRAQGVGRNVALEVPHFVALPGVLQVT
DLYATLPKRLAQILNRDNAFRLYALPVPLPPAPVTMHWHEHFHEDEGITWMRALLAEIVERFDGA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=29.0969899665552, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=26.8852459016393, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081766, Length=273, Percent_Identity=26.3736263736264, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786820, Length=292, Percent_Identity=23.6301369863014, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081904, Length=162, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34234; Mature: 34103

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVDHLDLNLLRVFQAIVEERSLTKAGERLALSQPAVSYSLGRLRTLFDDPLFVRTRAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCC
MQPTPVALELAGIVGKALDMVRVALRYAERFDPATSTRTFRLSLSDAGEMAYLPAICRAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
RERAPRVTLSVQPMPVEAIEEALRASRLDFAIGNLPELMPRTRHQLLFEETYVCMTGRRR
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCC
GLPSGTTLTLEQFVRAAHVNVKSVEHSHHALDDALRAQGVGRNVALEVPHFVALPGVLQV
CCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCHHHH
TDLYATLPKRLAQILNRDNAFRLYALPVPLPPAPVTMHWHEHFHEDEGITWMRALLAEIV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHH
ERFDGA
HHHCCC
>Mature Secondary Structure 
TSVDHLDLNLLRVFQAIVEERSLTKAGERLALSQPAVSYSLGRLRTLFDDPLFVRTRAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCC
MQPTPVALELAGIVGKALDMVRVALRYAERFDPATSTRTFRLSLSDAGEMAYLPAICRAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
RERAPRVTLSVQPMPVEAIEEALRASRLDFAIGNLPELMPRTRHQLLFEETYVCMTGRRR
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCC
GLPSGTTLTLEQFVRAAHVNVKSVEHSHHALDDALRAQGVGRNVALEVPHFVALPGVLQV
CCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCHHHH
TDLYATLPKRLAQILNRDNAFRLYALPVPLPPAPVTMHWHEHFHEDEGITWMRALLAEIV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHH
ERFDGA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]