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The map label for this gene is dctS [H]

Identifier: 189352216

GI number: 189352216

Start: 255067

End: 256620

Strand: Direct

Name: dctS [H]

Synonym: BMULJ_03434

Alternate gene names: 189352216

Gene position: 255067-256620 (Clockwise)

Preceding gene: 189352210

Following gene: 189352220

Centisome position: 10.31

GC content: 69.56

Gene sequence:

>1554_bases
ATGCGATCGACGCGGGCCGGTGCTATGTTGGGCGTCCGCCCGCGCGATGCCGCGCGGCTCGTTCCGGACCCGACCATGCG
CTTTCCCGACGAAGACGATTTCCACCGGCTGCTCGATGCGTTGACGACCTGCGTGCTGCTGCACGACGCACAGACCAAGG
CGATCGTCTGGGCCAACCGTGCGGCCTGCATCGCGCTCGGCTTTTCCGTCGAGGAACTGCTGCCGCTGAAGGCGCCGGAC
ATGACGCGGCCGGAGCCGAAATACCGTCGCGAGATCGGCGTCGGCGCGATGGACCGCGCGATCGTCGAAGGCCCGCAGGT
GTACGAGTGGTGCTACCGGTCGCGTACGGGCGTCGACATGCTGTCCGAGGCGATCGCGACCTACGTGCCGCTGCGCGGGC
GCGACGTCGTCATGGTGCAGTTTCGCGACATCAGCGCCGAGGAGGCGATCCGTCAGCAGCTGCGCCGCTACGAGGCGCGG
CTGCGCGAATTCATGCAGGATCTCGACGAAGGGATCGCGGTCGTGACGCCGCATGGCGGCGTGCAGTTCATCAGCGAGTC
GGGGCGCCGCGTGCTCGGCCTCGCGGCCGACGAGGCGGTCGGCGACGTGCTCGATTACTGCAGCGCGGACGATCGTGCGC
GGCTCGTCGCGCAATTGCGCGATGCGCCGTCGACGTGTCCGTCGGAACCGCAGCGCTACCGGTTCGTGCGGCGCGACGGC
TCGACGTGCTGGTTGCGCGTCGCGTGCCGGCAGGTGGAGATCGAAGGCGATCTCGACGGGCTGCTCGTGCATTTTCGCGA
CGTGAGCGACGAAGTCGCGATCGAGGAGGCGCGCCGCGCGGAAGCGCGGATGCTCGAGTACGCGGGCCGCTACAACGCGA
TGGGCGAGATGGCGACCGTGATCGCGCACGAGCTGAGCCAGCCGCTCGCGGCCGTGCGCAACTTCATCGAGGGTGCGGTG
CAGCGGCTCGGCGCGCGCGGCAACGTCGACGACGCGATCTGGGGGCTGCGCAGCGCCGACCGGCAGGCCGAGCATGCGGC
GCTGATCATCAAGAGCGTGCGCGAATTCATCGTGAAGCGCGAACCGGTCGTCGTGCTTGCCGACCTGCGCGACATCCTCG
CCGACGTCGCCTACTTCATCGAGCTGCGCGCGCGCGAAGCGGGCGTGACGGTGTCGATCGTGCAGGCCGACGTGCCGCTG
CCAGTCCGCTGCGAACGCGTGCTGATCGGGCAGGTAATCCTGAATCTCGCATTCAACGCGATCGAGGCCTTCGCCGGCTG
CGAGCGCGCGACACGCATGCTGACGCTCGGCACCGCGCAGGTCGGCGCGCTCGCGGAGCTGCGTGCGATCGATAACGGGC
CCGGTGTGGCCGACGATGCGCACGATCGGCTGTTCGACGGTTTTTCGTCGTCGAAGGCGGGCGGCAACGGCATCGGACTG
TCGCTCTGCAAGAGCATCGTGACGCGTCACGGTGGCCGCATCGCCGCGCGTCGCGCCGAGGGCGGCGGCCTCGACTGCCG
CGTGACGCTGCCGCTCGCCGACGCAGGCGCGTAG

Upstream 100 bases:

>100_bases
AAAGACAGGCCCCAGTCTAGGAACGCCGAAAACACGCAGCAATTGGTGCGCTAGGCCGCGCGACTGGTGACGTTCCGTGC
CGTCCTAAAGAAATCTTCAG

Downstream 100 bases:

>100_bases
CGCAGGGCGCGTGTTGCGGGCGGCCGGCGGCGTGCGTGGCACGATCAGCGCCCCAATGCGCGTGCGGTTTGGCCGCCGAT
CCCGAAGTCGGTATTCGGGA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRSTRAGAMLGVRPRDAARLVPDPTMRFPDEDDFHRLLDALTTCVLLHDAQTKAIVWANRAACIALGFSVEELLPLKAPD
MTRPEPKYRREIGVGAMDRAIVEGPQVYEWCYRSRTGVDMLSEAIATYVPLRGRDVVMVQFRDISAEEAIRQQLRRYEAR
LREFMQDLDEGIAVVTPHGGVQFISESGRRVLGLAADEAVGDVLDYCSADDRARLVAQLRDAPSTCPSEPQRYRFVRRDG
STCWLRVACRQVEIEGDLDGLLVHFRDVSDEVAIEEARRAEARMLEYAGRYNAMGEMATVIAHELSQPLAAVRNFIEGAV
QRLGARGNVDDAIWGLRSADRQAEHAALIIKSVREFIVKREPVVVLADLRDILADVAYFIELRAREAGVTVSIVQADVPL
PVRCERVLIGQVILNLAFNAIEAFAGCERATRMLTLGTAQVGALAELRAIDNGPGVADDAHDRLFDGFSSSKAGGNGIGL
SLCKSIVTRHGGRIAARRAEGGGLDCRVTLPLADAGA

Sequences:

>Translated_517_residues
MRSTRAGAMLGVRPRDAARLVPDPTMRFPDEDDFHRLLDALTTCVLLHDAQTKAIVWANRAACIALGFSVEELLPLKAPD
MTRPEPKYRREIGVGAMDRAIVEGPQVYEWCYRSRTGVDMLSEAIATYVPLRGRDVVMVQFRDISAEEAIRQQLRRYEAR
LREFMQDLDEGIAVVTPHGGVQFISESGRRVLGLAADEAVGDVLDYCSADDRARLVAQLRDAPSTCPSEPQRYRFVRRDG
STCWLRVACRQVEIEGDLDGLLVHFRDVSDEVAIEEARRAEARMLEYAGRYNAMGEMATVIAHELSQPLAAVRNFIEGAV
QRLGARGNVDDAIWGLRSADRQAEHAALIIKSVREFIVKREPVVVLADLRDILADVAYFIELRAREAGVTVSIVQADVPL
PVRCERVLIGQVILNLAFNAIEAFAGCERATRMLTLGTAQVGALAELRAIDNGPGVADDAHDRLFDGFSSSKAGGNGIGL
SLCKSIVTRHGGRIAARRAEGGGLDCRVTLPLADAGA
>Mature_517_residues
MRSTRAGAMLGVRPRDAARLVPDPTMRFPDEDDFHRLLDALTTCVLLHDAQTKAIVWANRAACIALGFSVEELLPLKAPD
MTRPEPKYRREIGVGAMDRAIVEGPQVYEWCYRSRTGVDMLSEAIATYVPLRGRDVVMVQFRDISAEEAIRQQLRRYEAR
LREFMQDLDEGIAVVTPHGGVQFISESGRRVLGLAADEAVGDVLDYCSADDRARLVAQLRDAPSTCPSEPQRYRFVRRDG
STCWLRVACRQVEIEGDLDGLLVHFRDVSDEVAIEEARRAEARMLEYAGRYNAMGEMATVIAHELSQPLAAVRNFIEGAV
QRLGARGNVDDAIWGLRSADRQAEHAALIIKSVREFIVKREPVVVLADLRDILADVAYFIELRAREAGVTVSIVQADVPL
PVRCERVLIGQVILNLAFNAIEAFAGCERATRMLTLGTAQVGALAELRAIDNGPGVADDAHDRLFDGFSSSKAGGNGIGL
SLCKSIVTRHGGRIAARRAEGGGLDCRVTLPLADAGA

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=24.802110817942, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=25.1121076233184, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56715; Mature: 56715

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTRAGAMLGVRPRDAARLVPDPTMRFPDEDDFHRLLDALTTCVLLHDAQTKAIVWANR
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AACIALGFSVEELLPLKAPDMTRPEPKYRREIGVGAMDRAIVEGPQVYEWCYRSRTGVDM
CEEEEECCCHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCHHH
LSEAIATYVPLRGRDVVMVQFRDISAEEAIRQQLRRYEARLREFMQDLDEGIAVVTPHGG
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
VQFISESGRRVLGLAADEAVGDVLDYCSADDRARLVAQLRDAPSTCPSEPQRYRFVRRDG
HHHHHHCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
STCWLRVACRQVEIEGDLDGLLVHFRDVSDEVAIEEARRAEARMLEYAGRYNAMGEMATV
CEEEEEEEEHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHELSQPLAAVRNFIEGAVQRLGARGNVDDAIWGLRSADRQAEHAALIIKSVREFIVKR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVVVLADLRDILADVAYFIELRAREAGVTVSIVQADVPLPVRCERVLIGQVILNLAFNA
CCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IEAFAGCERATRMLTLGTAQVGALAELRAIDNGPGVADDAHDRLFDGFSSSKAGGNGIGL
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHH
SLCKSIVTRHGGRIAARRAEGGGLDCRVTLPLADAGA
HHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRSTRAGAMLGVRPRDAARLVPDPTMRFPDEDDFHRLLDALTTCVLLHDAQTKAIVWANR
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AACIALGFSVEELLPLKAPDMTRPEPKYRREIGVGAMDRAIVEGPQVYEWCYRSRTGVDM
CEEEEECCCHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCHHH
LSEAIATYVPLRGRDVVMVQFRDISAEEAIRQQLRRYEARLREFMQDLDEGIAVVTPHGG
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
VQFISESGRRVLGLAADEAVGDVLDYCSADDRARLVAQLRDAPSTCPSEPQRYRFVRRDG
HHHHHHCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
STCWLRVACRQVEIEGDLDGLLVHFRDVSDEVAIEEARRAEARMLEYAGRYNAMGEMATV
CEEEEEEEEHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHELSQPLAAVRNFIEGAVQRLGARGNVDDAIWGLRSADRQAEHAALIIKSVREFIVKR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVVVLADLRDILADVAYFIELRAREAGVTVSIVQADVPLPVRCERVLIGQVILNLAFNA
CCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IEAFAGCERATRMLTLGTAQVGALAELRAIDNGPGVADDAHDRLFDGFSSSKAGGNGIGL
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHH
SLCKSIVTRHGGRIAARRAEGGGLDCRVTLPLADAGA
HHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]