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The map label for this gene is codA [C]

Identifier: 189184848

GI number: 189184848

Start: 1976628

End: 1977095

Strand: Reverse

Name: codA [C]

Synonym: OTT_1941

Alternate gene names: 189184848

Gene position: 1977095-1976628 (Counterclockwise)

Preceding gene: 189184849

Following gene: 189184847

Centisome position: 98.41

GC content: 32.05

Gene sequence:

>468_bases
ATGTTTATGTTACAAGCAATAGAGCAGGCTTCGCAGGCTTTTAACTTAGGTGAAGTACCTGTAGGAGTAGTTATGGTTAA
TCGAGCAACAAGAACTATATTAACTAGAGCTTATAATAAAGTTGAAACTACATTAAATCCTACTTTTCATGCTGAAATTA
TTGCAATTAATAAAGCTTGCAGTTTGTTAAGCTGCAAATACTTACATGGTTATGATATTTATGTTAGCTTAGAACCATGC
GCAATGTGCGCTGCTGCGTTATCTCATGTTAGAATTGATCGTATATTTTTTGGAGCATATGATGAAAAGTTTGGTGCTAT
AGAAAACGGTGTACGGCTCTTTTATAATACAACGGTATATTATAAACCAGAAATATATGGTGGTATTATGGAGTTGCAAT
CTAAGGAATTATTACAAAAGTTTTTTAGTAATCTCAGAGTAAAGAATGAAACAAAGTGTATAATGTAA

Upstream 100 bases:

>100_bases
CCTGCTGGCTATGAACAGTGCGTAATGTATCAAGAGAAAATTTGATATACGTGTAACTCTTTAATTATTTATTAGGGAAA
AATATTATCATATTATAGCT

Downstream 100 bases:

>100_bases
ATGTTAAAAATTGCAAAAATTGGAGTATTATAGTTTATAGTTTATTAAACATCATACATAAAAATGAATAAGCTAGATAT
TAGCACGATTAATATTGAAC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MFMLQAIEQASQAFNLGEVPVGVVMVNRATRTILTRAYNKVETTLNPTFHAEIIAINKACSLLSCKYLHGYDIYVSLEPC
AMCAAALSHVRIDRIFFGAYDEKFGAIENGVRLFYNTTVYYKPEIYGGIMELQSKELLQKFFSNLRVKNETKCIM

Sequences:

>Translated_155_residues
MFMLQAIEQASQAFNLGEVPVGVVMVNRATRTILTRAYNKVETTLNPTFHAEIIAINKACSLLSCKYLHGYDIYVSLEPC
AMCAAALSHVRIDRIFFGAYDEKFGAIENGVRLFYNTTVYYKPEIYGGIMELQSKELLQKFFSNLRVKNETKCIM
>Mature_155_residues
MFMLQAIEQASQAFNLGEVPVGVVMVNRATRTILTRAYNKVETTLNPTFHAEIIAINKACSLLSCKYLHGYDIYVSLEPC
AMCAAALSHVRIDRIFFGAYDEKFGAIENGVRLFYNTTVYYKPEIYGGIMELQSKELLQKFFSNLRVKNETKCIM

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=114, Percent_Identity=35.0877192982456, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI145693172, Length=145, Percent_Identity=34.4827586206897, Blast_Score=93, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17541138, Length=154, Percent_Identity=33.7662337662338, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=115, Percent_Identity=31.304347826087, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=118, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355527, Length=151, Percent_Identity=31.1258278145695, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17598; Mature: 17598

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMLQAIEQASQAFNLGEVPVGVVMVNRATRTILTRAYNKVETTLNPTFHAEIIAINKAC
CHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHH
SLLSCKYLHGYDIYVSLEPCAMCAAALSHVRIDRIFFGAYDEKFGAIENGVRLFYNTTVY
HHHEEHEECCEEEEEEECHHHHHHHHHHHHHHHHEEECCCCCCCCHHHCCEEEEEEEEEE
YKPEIYGGIMELQSKELLQKFFSNLRVKNETKCIM
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFMLQAIEQASQAFNLGEVPVGVVMVNRATRTILTRAYNKVETTLNPTFHAEIIAINKAC
CHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHH
SLLSCKYLHGYDIYVSLEPCAMCAAALSHVRIDRIFFGAYDEKFGAIENGVRLFYNTTVY
HHHEEHEECCEEEEEEECHHHHHHHHHHHHHHHHEEECCCCCCCCHHHCCEEEEEEEEEE
YKPEIYGGIMELQSKELLQKFFSNLRVKNETKCIM
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA