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The map label for this gene is pbpE [H]

Identifier: 189184698

GI number: 189184698

Start: 1816173

End: 1817384

Strand: Reverse

Name: pbpE [H]

Synonym: OTT_1791

Alternate gene names: 189184698

Gene position: 1817384-1816173 (Counterclockwise)

Preceding gene: 189184699

Following gene: 189184694

Centisome position: 90.46

GC content: 29.79

Gene sequence:

>1212_bases
ATGAAGATAATGAAAATAACAAAATTTTATATTTTATTAGTATTGATTTTACTACTAATACCAAGCGCTTCTTTTGCTAA
AAGCAATAAAACTATGAGTAAGGATATTAGTAACTATCTAAAGAATATGAATATTAATGCTAGTTATTATATTGCTACTG
ATAAAAATAAAATTATTGCTCGAGGAGCAGTAGGGCATTTTGATTGCAGTACAAAACAACATAAAATAAAGTATGATGTT
TTGATGCCAATTGCTTCTATTACTAAATCAATGACTGCAGTTGCTATTATGATTCTGTATGAGCAGGGAAAATTAAAGTT
AGATGATTGTATTGCTAAACATATACCTGAGAATTATTGGCCTAATGGCAAGATTCCTACTTGGAGTAATACAGTAAGTA
TTCATCAGCTGCTGAGTCATACTAGCGGTATAGTTGATCCTAAAGGTATAAACAGTTCAGATGTTTCTAAAAAGTTGTTT
AGACCAGAAATGAGTGATATGGAAATTAAACAAATTATATTAAATTCCATTGTTGATCAGCAGTTACACTCTGTTGGGCA
GTACCATTATTCTAATATAGGGTATTTTATTTTAGGGCTGATCATTGAGAATGTGAGTAAGCAAGAACTAAAAGATTTTT
TTGCTGAAAATTTATTTAAACCGCTAAAAATGAATAATACATACCTATTAACTTTTCAAGAAGGATTCAAGATACAAATG
CTAGGTAGTAAAAGAATTCCAGATACATGTGTGTTTCAGCGTGATATGAATCAGAAAGATGTATCATTAGTAAAATTACA
GAGTAGGGTGCTTGCTACTTTTTCTGCAGGAGGAGTTATATCTAATGTGCATGATCTCCATAAATGGAATTTAGCTTTAC
ATAATATGCAAATTGTTAGTAAGGATTCATATATAAAAATGACAACATCGCATGCTGTGATTAATGATACAGATGAAAAT
GAGTTATTTACAGAGTCATATTACGGGTATGGATTAAAAATTGGATTATTGGCTAATGGAAAGAAAGTTTATGGTCATAA
TGGTAATTATTGTGCAAGAAGTGAGTTATGGTATGTACCATCTAAGTCAGTTAGTATTGCAATGCTAAGTAATGTCTTTA
TACCTAAATTATTAATTAATGATCCTGCTGCAGAGCAGTTTAATGTTCAATCATTATTGAATTATGTGATAACTAGACTC
TATTGTTGTTAA

Upstream 100 bases:

>100_bases
GCTCCTTCAGCTGTAACTGAGAAACAATTACAGGAGTTACAGCTAAAGTTAATATCTAAAGAAAGAATTAAATAAATTAT
TTTAATAAAAGAATATAGAT

Downstream 100 bases:

>100_bases
AAGAAAAAACAAATAGCAATGCAACTAAATGGTTTTATCTAAGAATATTCTATTGGCTGGTTGCTACTTTTATAGTCATT
TACCAATGAAGTTTGCGTAT

Product: penicillin-binding protein 4

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKIMKITKFYILLVLILLLIPSASFAKSNKTMSKDISNYLKNMNINASYYIATDKNKIIARGAVGHFDCSTKQHKIKYDV
LMPIASITKSMTAVAIMILYEQGKLKLDDCIAKHIPENYWPNGKIPTWSNTVSIHQLLSHTSGIVDPKGINSSDVSKKLF
RPEMSDMEIKQIILNSIVDQQLHSVGQYHYSNIGYFILGLIIENVSKQELKDFFAENLFKPLKMNNTYLLTFQEGFKIQM
LGSKRIPDTCVFQRDMNQKDVSLVKLQSRVLATFSAGGVISNVHDLHKWNLALHNMQIVSKDSYIKMTTSHAVINDTDEN
ELFTESYYGYGLKIGLLANGKKVYGHNGNYCARSELWYVPSKSVSIAMLSNVFIPKLLINDPAAEQFNVQSLLNYVITRL
YCC

Sequences:

>Translated_403_residues
MKIMKITKFYILLVLILLLIPSASFAKSNKTMSKDISNYLKNMNINASYYIATDKNKIIARGAVGHFDCSTKQHKIKYDV
LMPIASITKSMTAVAIMILYEQGKLKLDDCIAKHIPENYWPNGKIPTWSNTVSIHQLLSHTSGIVDPKGINSSDVSKKLF
RPEMSDMEIKQIILNSIVDQQLHSVGQYHYSNIGYFILGLIIENVSKQELKDFFAENLFKPLKMNNTYLLTFQEGFKIQM
LGSKRIPDTCVFQRDMNQKDVSLVKLQSRVLATFSAGGVISNVHDLHKWNLALHNMQIVSKDSYIKMTTSHAVINDTDEN
ELFTESYYGYGLKIGLLANGKKVYGHNGNYCARSELWYVPSKSVSIAMLSNVFIPKLLINDPAAEQFNVQSLLNYVITRL
YCC
>Mature_403_residues
MKIMKITKFYILLVLILLLIPSASFAKSNKTMSKDISNYLKNMNINASYYIATDKNKIIARGAVGHFDCSTKQHKIKYDV
LMPIASITKSMTAVAIMILYEQGKLKLDDCIAKHIPENYWPNGKIPTWSNTVSIHQLLSHTSGIVDPKGINSSDVSKKLF
RPEMSDMEIKQIILNSIVDQQLHSVGQYHYSNIGYFILGLIIENVSKQELKDFFAENLFKPLKMNNTYLLTFQEGFKIQM
LGSKRIPDTCVFQRDMNQKDVSLVKLQSRVLATFSAGGVISNVHDLHKWNLALHNMQIVSKDSYIKMTTSHAVINDTDEN
ELFTESYYGYGLKIGLLANGKKVYGHNGNYCARSELWYVPSKSVSIAMLSNVFIPKLLINDPAAEQFNVQSLLNYVITRL
YCC

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786574, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533026, Length=290, Percent_Identity=27.2413793103448, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 45698; Mature: 45698

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMKITKFYILLVLILLLIPSASFAKSNKTMSKDISNYLKNMNINASYYIATDKNKIIA
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEE
RGAVGHFDCSTKQHKIKYDVLMPIASITKSMTAVAIMILYEQGKLKLDDCIAKHIPENYW
ECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEEECCCEEHHHHHHHHCCCCCC
PNGKIPTWSNTVSIHQLLSHTSGIVDPKGINSSDVSKKLFRPEMSDMEIKQIILNSIVDQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QLHSVGQYHYSNIGYFILGLIIENVSKQELKDFFAENLFKPLKMNNTYLLTFQEGFKIQM
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEE
LGSKRIPDTCVFQRDMNQKDVSLVKLQSRVLATFSAGGVISNVHDLHKWNLALHNMQIVS
ECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEE
KDSYIKMTTSHAVINDTDENELFTESYYGYGLKIGLLANGKKVYGHNGNYCARSELWYVP
CCCEEEEEECCEEECCCCCCCEEHHHHCCCCEEEEEEECCCEEECCCCCEEECCCEEECC
SKSVSIAMLSNVFIPKLLINDPAAEQFNVQSLLNYVITRLYCC
CCCEEHHHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIMKITKFYILLVLILLLIPSASFAKSNKTMSKDISNYLKNMNINASYYIATDKNKIIA
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEE
RGAVGHFDCSTKQHKIKYDVLMPIASITKSMTAVAIMILYEQGKLKLDDCIAKHIPENYW
ECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEEECCCEEHHHHHHHHCCCCCC
PNGKIPTWSNTVSIHQLLSHTSGIVDPKGINSSDVSKKLFRPEMSDMEIKQIILNSIVDQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QLHSVGQYHYSNIGYFILGLIIENVSKQELKDFFAENLFKPLKMNNTYLLTFQEGFKIQM
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEE
LGSKRIPDTCVFQRDMNQKDVSLVKLQSRVLATFSAGGVISNVHDLHKWNLALHNMQIVS
ECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEE
KDSYIKMTTSHAVINDTDENELFTESYYGYGLKIGLLANGKKVYGHNGNYCARSELWYVP
CCCEEEEEECCEEECCCCCCCEEHHHHCCCCEEEEEEECCCEEECCCCCEEECCCEEECC
SKSVSIAMLSNVFIPKLLINDPAAEQFNVQSLLNYVITRLYCC
CCCEEHHHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA