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The map label for this gene is xseA [H]

Identifier: 189184650

GI number: 189184650

Start: 1766849

End: 1768219

Strand: Reverse

Name: xseA [H]

Synonym: OTT_1743

Alternate gene names: 189184650

Gene position: 1768219-1766849 (Counterclockwise)

Preceding gene: 189184651

Following gene: 189184649

Centisome position: 88.02

GC content: 32.53

Gene sequence:

>1371_bases
ATGCATGCAAAAAATATAAGTGGTTTTGATGTTAACTATCTAAGTGACGAATGCAATGCCAAGGAATATACAGTTCATGA
GCTTTCGTTGCACATAAAATCAGCTATTGAATATCAGTTCGGCGTGCTAAAAGTACGAGGTGAAGTTTCTGGATTAAAAA
TTGCTAGTTCATGTCATAGCTATTTTAACTTAAAAGACGATAAAGCAGTTTTAAATTGTGTATGTTGGAAAACAACTTTA
AATCTTGTAAAAATTAAGGTTGAAGATGGAATAGAGGTTATAGCTACTGGTAGGCTCACTACTTATTCAGGCCAATCTAG
ATATCAGCTTGTAGTTGAAAATATTTGTATTGCTGGGTTAGGATCATTGATGCAAATATTTTTTCAACGTAAAGAAAAAT
TAATGAAAGAAGGGCTGTTTGATAATTCTAGAAAAAAAAAGCTACCAGCCTTTCCAATGGTTATTGGAGTCATAACATCT
ATTTCTGGCGCTGTTATCAGAGATATTGCGCATCGAGTTAATGACCGCTTTCCTAGCAAATTATTAGTATGGCCAGTAAC
GGTACAAGGCAATAATTCTGCTAATGAGGTAGCAAGTGCTATTCAAGAATGTAACAATATGCTAACTAGTAACAATGATC
TAGCTCCCGAAGTTATTATTATAGCTAGAGGTGGTGGATCTGTGGAAGATTTATGGTCATTTAATGAAGAAATTGTTGTT
AGGGCTATAGCTAGCTCAGTTATTCCAATAGTATCAGCTATTGGCCACGAAGTAGATTTTACTCTTGCAGATTTTGCTGC
TGACCTAAGAGCTCCAACGCCATCAGCTGCTGCTGAGATGGTAGTGCCAGTTTTAGCTGATATAAAAATGCGTTTAAATA
ATTCAATGAACCAGATAAATCATGTTACTTTCAATTATTTAAAATGTAGTGTTATGTCGCTGAATAATTGTGGTAATATT
GTTCAAAAGCTAAAAACAATGATAGATTTAAATTATCAAAAATTTGATGAGCTTGTATTTCGATTTGATACAAAAGTAGA
GCAATTTGGAGAACTTCAAAAAAGAATTTTACAAAATAATGTGCTTATTGATCCTAGTAAATTGGTGCAATTATACGCAC
TGAAACTTGAAAACCTTAATAATAAGTTATATCAACTTGTAAAAAGATTATTTGTTAACTTAGATAACAAAGTGTATTTG
TTAGATTCTCTCTTAAATAATATGGATTATTCAAGAGTACTTAAAAGAGGATTTGCCATTATAAGATTAGTAGACGGACC
AGTGGTATCTTCATTGTCTCAGCTTAAAGGTAATGACAAAATAAAGATACAATTACAAGACGGAGTACGACAAGCTACAA
TTGATTCTTAA

Upstream 100 bases:

>100_bases
GTCATTGTGTTGCTAAATTAAGTTAGCGTATTTTTTATCATAAAATAAAAAATTTTAGTATAAAATGAAATTATTGATTA
TATAAAAAAAATGAATTTTT

Downstream 100 bases:

>100_bases
TTGATATTAGCTGCATTTTTTACTGTTTAAAATTTTATGTGATTATTAAGCTTATATTATGTCGCATTATAAAAGTACAT
TATTTATATTATTATTGCTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MHAKNISGFDVNYLSDECNAKEYTVHELSLHIKSAIEYQFGVLKVRGEVSGLKIASSCHSYFNLKDDKAVLNCVCWKTTL
NLVKIKVEDGIEVIATGRLTTYSGQSRYQLVVENICIAGLGSLMQIFFQRKEKLMKEGLFDNSRKKKLPAFPMVIGVITS
ISGAVIRDIAHRVNDRFPSKLLVWPVTVQGNNSANEVASAIQECNNMLTSNNDLAPEVIIIARGGGSVEDLWSFNEEIVV
RAIASSVIPIVSAIGHEVDFTLADFAADLRAPTPSAAAEMVVPVLADIKMRLNNSMNQINHVTFNYLKCSVMSLNNCGNI
VQKLKTMIDLNYQKFDELVFRFDTKVEQFGELQKRILQNNVLIDPSKLVQLYALKLENLNNKLYQLVKRLFVNLDNKVYL
LDSLLNNMDYSRVLKRGFAIIRLVDGPVVSSLSQLKGNDKIKIQLQDGVRQATIDS

Sequences:

>Translated_456_residues
MHAKNISGFDVNYLSDECNAKEYTVHELSLHIKSAIEYQFGVLKVRGEVSGLKIASSCHSYFNLKDDKAVLNCVCWKTTL
NLVKIKVEDGIEVIATGRLTTYSGQSRYQLVVENICIAGLGSLMQIFFQRKEKLMKEGLFDNSRKKKLPAFPMVIGVITS
ISGAVIRDIAHRVNDRFPSKLLVWPVTVQGNNSANEVASAIQECNNMLTSNNDLAPEVIIIARGGGSVEDLWSFNEEIVV
RAIASSVIPIVSAIGHEVDFTLADFAADLRAPTPSAAAEMVVPVLADIKMRLNNSMNQINHVTFNYLKCSVMSLNNCGNI
VQKLKTMIDLNYQKFDELVFRFDTKVEQFGELQKRILQNNVLIDPSKLVQLYALKLENLNNKLYQLVKRLFVNLDNKVYL
LDSLLNNMDYSRVLKRGFAIIRLVDGPVVSSLSQLKGNDKIKIQLQDGVRQATIDS
>Mature_456_residues
MHAKNISGFDVNYLSDECNAKEYTVHELSLHIKSAIEYQFGVLKVRGEVSGLKIASSCHSYFNLKDDKAVLNCVCWKTTL
NLVKIKVEDGIEVIATGRLTTYSGQSRYQLVVENICIAGLGSLMQIFFQRKEKLMKEGLFDNSRKKKLPAFPMVIGVITS
ISGAVIRDIAHRVNDRFPSKLLVWPVTVQGNNSANEVASAIQECNNMLTSNNDLAPEVIIIARGGGSVEDLWSFNEEIVV
RAIASSVIPIVSAIGHEVDFTLADFAADLRAPTPSAAAEMVVPVLADIKMRLNNSMNQINHVTFNYLKCSVMSLNNCGNI
VQKLKTMIDLNYQKFDELVFRFDTKVEQFGELQKRILQNNVLIDPSKLVQLYALKLENLNNKLYQLVKRLFVNLDNKVYL
LDSLLNNMDYSRVLKRGFAIIRLVDGPVVSSLSQLKGNDKIKIQLQDGVRQATIDS

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=433, Percent_Identity=31.8706697459584, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50982; Mature: 50982

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAKNISGFDVNYLSDECNAKEYTVHELSLHIKSAIEYQFGVLKVRGEVSGLKIASSCHS
CCCCCCCCCCCEECCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
YFNLKDDKAVLNCVCWKTTLNLVKIKVEDGIEVIATGRLTTYSGQSRYQLVVENICIAGL
HCCCCCCHHHHHHHHHHEEEEEEEEEEECCEEEEEECCEEEECCCCHHHHHHHHHHHHHH
GSLMQIFFQRKEKLMKEGLFDNSRKKKLPAFPMVIGVITSISGAVIRDIAHRVNDRFPSK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
LLVWPVTVQGNNSANEVASAIQECNNMLTSNNDLAPEVIIIARGGGSVEDLWSFNEEIVV
EEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHH
RAIASSVIPIVSAIGHEVDFTLADFAADLRAPTPSAAAEMVVPVLADIKMRLNNSMNQIN
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
HVTFNYLKCSVMSLNNCGNIVQKLKTMIDLNYQKFDELVFRFDTKVEQFGELQKRILQNN
HHEEHHHEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLIDPSKLVQLYALKLENLNNKLYQLVKRLFVNLDNKVYLLDSLLNNMDYSRVLKRGFAI
CEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHCCCEE
IRLVDGPVVSSLSQLKGNDKIKIQLQDGVRQATIDS
EEEECCHHHHHHHHHCCCCEEEEEECCCCCHHCCCC
>Mature Secondary Structure
MHAKNISGFDVNYLSDECNAKEYTVHELSLHIKSAIEYQFGVLKVRGEVSGLKIASSCHS
CCCCCCCCCCCEECCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
YFNLKDDKAVLNCVCWKTTLNLVKIKVEDGIEVIATGRLTTYSGQSRYQLVVENICIAGL
HCCCCCCHHHHHHHHHHEEEEEEEEEEECCEEEEEECCEEEECCCCHHHHHHHHHHHHHH
GSLMQIFFQRKEKLMKEGLFDNSRKKKLPAFPMVIGVITSISGAVIRDIAHRVNDRFPSK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
LLVWPVTVQGNNSANEVASAIQECNNMLTSNNDLAPEVIIIARGGGSVEDLWSFNEEIVV
EEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHH
RAIASSVIPIVSAIGHEVDFTLADFAADLRAPTPSAAAEMVVPVLADIKMRLNNSMNQIN
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
HVTFNYLKCSVMSLNNCGNIVQKLKTMIDLNYQKFDELVFRFDTKVEQFGELQKRILQNN
HHEEHHHEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLIDPSKLVQLYALKLENLNNKLYQLVKRLFVNLDNKVYLLDSLLNNMDYSRVLKRGFAI
CEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHCCCEE
IRLVDGPVVSSLSQLKGNDKIKIQLQDGVRQATIDS
EEEECCHHHHHHHHHCCCCEEEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA