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The map label for this gene is 189184392

Identifier: 189184392

GI number: 189184392

Start: 1515258

End: 1516403

Strand: Reverse

Name: 189184392

Synonym: OTT_1485

Alternate gene names: NA

Gene position: 1516403-1515258 (Counterclockwise)

Preceding gene: 189184393

Following gene: 189184391

Centisome position: 75.48

GC content: 28.88

Gene sequence:

>1146_bases
ATGAAAAATATATATAAATTAGCTATAACAATAATTTTACCACTAATGCTTTTAAATACAGCTATTCCTGCAGAAGAAAG
CAAGCTAGTTCAACAAAATAGCATTAAAGACAAAAATGTTTTAGCTAAAGAATATTCCAATATTGGAAGTTCTTTTTTAA
GGCTAAAAAAATATCATGAAGCAATAGAAAATTTTGATATTGCTATTAAGCATGATCCAAGTTATGCGTCAGCATATAAT
AGTAAAGGAATAGCTTTAGCTGATCTTGGAAAGGCACTAGAAGCTGTAGAAAATTATGATTTAGCTATTAAGCACAAACC
TCATTTTGCAGAAGCATATAATAATAAAGCTGTATCTTATAGAAAATTAGGAAAAAACGAAGAAGCTATAATACTTTGTG
ATCTTGCTATTAAATATAAGCCTAACTATGTAACTGCTTATAACAATAAAGGAGCAGCTTTAAATAACTTAGGGAGGTAT
GAAGAAGCAGTGGAAAACTTTGATGTTGCTATTAGGTATAACTCTAGTTACCCAGAAGCTTATTATAACAAAGGTATAGC
GTTAATGTATTTAGGCTACATTCAAGAAGCTATTGAAAACTATGATACAGCTATTAGATACAGACCAAATTATTCAGAAG
CATATCATAATAAAGGATTAACTTTAGCATTTTTAGGACAATTTCAGAAAGCAATAGAACATTTTGATTTAGCTATTAAA
TACGATCCTAATGATGCAACAGCATACTGTAATAAAGGTTATGTGCTAAGTATGTTAAAAAGGTATTCTGAAGCAATAGA
AAGCTGCAATCTAGCAATTAAATACAATCCGAATTGTGCTGAGGCTTACTACCGTAGAGGAATGATTTTTGAAAAATTAG
GTGAACAGCAAAAAGCGATAGAAAACTATGATATTGCTATTAAGTACAAACCTAATTTTGCTGAAAATTATCTTGAAAAA
GGAATTTCATTAGTAAGTTTAGGGCAGTACTCAAAAGCTAAAGAGAATTTTAAGTTAGCTATTAAATATATGCCTAATTT
TATAGCAGAATATGAAGCAACAATTAAAAGGTTAACAGAATTAGAGAATTTTACTATTGCAAAAGAATTTGAGCAAAAAC
TACAGATATTGAAAAAATACTCTTGA

Upstream 100 bases:

>100_bases
TTCTGATACTACTGATTCAACGGTTTTAATGGCTGGTAATCAAGCCTTGGAAAATCTTGGAATAACGAAAAAAGATAAAA
GTTAAAAGTATGTTGGATTT

Downstream 100 bases:

>100_bases
GATAGATGAATTTTCAGAATCAAGGAAATTTCACCAGAGGATCGCAGTTATTTGCCCATAAGTTAAGAATGTTTGGGCAA
GGTAGTACCAACGTTTTTAT

Product: TPR repeat-containing protein 01_09

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKNIYKLAITIILPLMLLNTAIPAEESKLVQQNSIKDKNVLAKEYSNIGSSFLRLKKYHEAIENFDIAIKHDPSYASAYN
SKGIALADLGKALEAVENYDLAIKHKPHFAEAYNNKAVSYRKLGKNEEAIILCDLAIKYKPNYVTAYNNKGAALNNLGRY
EEAVENFDVAIRYNSSYPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAIK
YDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGEQQKAIENYDIAIKYKPNFAENYLEK
GISLVSLGQYSKAKENFKLAIKYMPNFIAEYEATIKRLTELENFTIAKEFEQKLQILKKYS

Sequences:

>Translated_381_residues
MKNIYKLAITIILPLMLLNTAIPAEESKLVQQNSIKDKNVLAKEYSNIGSSFLRLKKYHEAIENFDIAIKHDPSYASAYN
SKGIALADLGKALEAVENYDLAIKHKPHFAEAYNNKAVSYRKLGKNEEAIILCDLAIKYKPNYVTAYNNKGAALNNLGRY
EEAVENFDVAIRYNSSYPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAIK
YDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGEQQKAIENYDIAIKYKPNFAENYLEK
GISLVSLGQYSKAKENFKLAIKYMPNFIAEYEATIKRLTELENFTIAKEFEQKLQILKKYS
>Mature_381_residues
MKNIYKLAITIILPLMLLNTAIPAEESKLVQQNSIKDKNVLAKEYSNIGSSFLRLKKYHEAIENFDIAIKHDPSYASAYN
SKGIALADLGKALEAVENYDLAIKHKPHFAEAYNNKAVSYRKLGKNEEAIILCDLAIKYKPNYVTAYNNKGAALNNLGRY
EEAVENFDVAIRYNSSYPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAIK
YDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGEQQKAIENYDIAIKYKPNFAENYLEK
GISLVSLGQYSKAKENFKLAIKYMPNFIAEYEATIKRLTELENFTIAKEFEQKLQILKKYS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=246, Percent_Identity=31.7073170731707, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32307148, Length=246, Percent_Identity=31.7073170731707, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI118766330, Length=281, Percent_Identity=27.0462633451957, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI118766328, Length=281, Percent_Identity=27.0462633451957, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310123097, Length=264, Percent_Identity=26.8939393939394, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310131789, Length=264, Percent_Identity=26.5151515151515, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310110582, Length=264, Percent_Identity=26.5151515151515, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI221219056, Length=288, Percent_Identity=25.6944444444444, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI262206280, Length=288, Percent_Identity=25.6944444444444, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI170784867, Length=314, Percent_Identity=26.4331210191083, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI83415184, Length=324, Percent_Identity=24.0740740740741, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI301336134, Length=324, Percent_Identity=24.0740740740741, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI224028289, Length=374, Percent_Identity=24.331550802139, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI22749211, Length=319, Percent_Identity=26.0188087774295, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI54607135, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI296531396, Length=211, Percent_Identity=25.5924170616114, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=348, Percent_Identity=26.4367816091954, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532690, Length=348, Percent_Identity=26.4367816091954, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25147174, Length=237, Percent_Identity=24.8945147679325, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319387, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647755, Length=293, Percent_Identity=30.7167235494881, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24585827, Length=293, Percent_Identity=30.7167235494881, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24585829, Length=293, Percent_Identity=30.7167235494881, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI161076610, Length=254, Percent_Identity=29.5275590551181, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920486, Length=254, Percent_Identity=29.5275590551181, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647123, Length=244, Percent_Identity=25.4098360655738, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137540, Length=228, Percent_Identity=23.6842105263158, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 43706; Mature: 43706

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIYKLAITIILPLMLLNTAIPAEESKLVQQNSIKDKNVLAKEYSNIGSSFLRLKKYHE
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIENFDIAIKHDPSYASAYNSKGIALADLGKALEAVENYDLAIKHKPHFAEAYNNKAVSY
HHHCCCEEEEECCCHHHHCCCCCEEHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCEEH
RKLGKNEEAIILCDLAIKYKPNYVTAYNNKGAALNNLGRYEEAVENFDVAIRYNSSYPEA
HHCCCCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHH
YYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAIK
HHHCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
YDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGEQQKAI
ECCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHCHHHHHH
ENYDIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFKLAIKYMPNFIAEYEATIKRLTE
CCCCEEEEECCCHHHHHHHCCCCEEECCCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LENFTIAKEFEQKLQILKKYS
HHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNIYKLAITIILPLMLLNTAIPAEESKLVQQNSIKDKNVLAKEYSNIGSSFLRLKKYHE
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIENFDIAIKHDPSYASAYNSKGIALADLGKALEAVENYDLAIKHKPHFAEAYNNKAVSY
HHHCCCEEEEECCCHHHHCCCCCEEHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCEEH
RKLGKNEEAIILCDLAIKYKPNYVTAYNNKGAALNNLGRYEEAVENFDVAIRYNSSYPEA
HHCCCCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHH
YYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAIK
HHHCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
YDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGEQQKAI
ECCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHCHHHHHH
ENYDIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFKLAIKYMPNFIAEYEATIKRLTE
CCCCEEEEECCCHHHHHHHCCCCEEECCCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LENFTIAKEFEQKLQILKKYS
HHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]