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The map label for this gene is coxW [H]

Identifier: 189183600

GI number: 189183600

Start: 721944

End: 723023

Strand: Direct

Name: coxW [H]

Synonym: OTT_0693

Alternate gene names: 189183600

Gene position: 721944-723023 (Clockwise)

Preceding gene: 189183597

Following gene: 189183601

Centisome position: 35.94

GC content: 27.96

Gene sequence:

>1080_bases
ATGGATAAGCCACATATTCAAATAATGTCAATCTGGTTAATAGTATCAACATTGCTATTATTACTTATGATTGTAGTAGG
AGGAATAACTAGATTGACTAATGCTGGTCTATCTATTGTAGAATGGAATCCAGTATCAGGAATTATACCTCCTATATCTT
CAGAAGATTGGAACAATGAGTTTAATAAATATACAGCTTCACCAGAATTTAATTTAATTAATAATCAGATAACTATTTCT
GAGTTTAAATATATCTTTTTTATCGAATATATTCATCGATTATTGGGAAGAATAACTGGAATAATAATCATTATACCATT
TTTAATCTTTTATTATTTAAAATCTTTAACTAAATTGCAATGTTACAGGTTACTTCTGATTACTTGTTTAGTGATAATAC
AAGGTTTTATGGGATGGTATATGGTAAAGAGTGGGTTAAAAGATACGCCGTATATTAATCACTGCCGACTAGCAGGGCAT
TTGTTATTAGCAGTTGTTATTTATCATCAATTAATAGCTGAGTTATTAATTATTATACAACCATTTAAATGCTATATGTT
AGCAACCAGCAAAGCTAATAACTCTAATAGTACAAGTATTAATGTTATTAACTTAAAAACAAAATTAATAGTCCTTAACA
AGATAATTATTTTTTTACTTTATACTCAGATTATGTTTGGAGCTTTAGTTGCTGGACTTGATGCAGGATTAATATACAAT
GAGTTTCCTAATATGGGTGATAGTTTAATTCCAATTGAAATATTAAATCAGTCTATAGATTTTACTATGTTTGATAATCA
AGTGTTGATGCAATTTATACATAGGTGGTTTGGCATACTAATTAGCTGCTTAATAATATGTTATGCTATTTGGCTAATTA
TTCTTAATAAACAAGCTCTAAGAGGAATGGGGATGGTAGCAGCATGTTTAGTTTTAGTTCAGGTTACTACTGGCATTATA
ACTTTGGTTTATCATGTACCAATATTAGCTGCTTTAACACATCAAGTAGGTGCTATTTTGATATTAACAACTTTCCTTTT
TATTCAAAATATAGTAACTAATTTTGAGCTATTACACTAG

Upstream 100 bases:

>100_bases
TTCTTTGATTTTTTATAGTATGTTAGGTTTACATGCTTAGTAGTCAATTAATGATTTTAAAATTGCTGATAAAGGCATAT
TAATTATATTTAGATACTAA

Downstream 100 bases:

>100_bases
GTACTTGAATTTATTGTAAGCATAACAGCTGCAAAGGTAATGAAGATAAGGAAAGAAAAATTCTTTACCTACTGAATCTA
CTGATAAAGTTGCAAAGACA

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDKPHIQIMSIWLIVSTLLLLLMIVVGGITRLTNAGLSIVEWNPVSGIIPPISSEDWNNEFNKYTASPEFNLINNQITIS
EFKYIFFIEYIHRLLGRITGIIIIIPFLIFYYLKSLTKLQCYRLLLITCLVIIQGFMGWYMVKSGLKDTPYINHCRLAGH
LLLAVVIYHQLIAELLIIIQPFKCYMLATSKANNSNSTSINVINLKTKLIVLNKIIIFLLYTQIMFGALVAGLDAGLIYN
EFPNMGDSLIPIEILNQSIDFTMFDNQVLMQFIHRWFGILISCLIICYAIWLIILNKQALRGMGMVAACLVLVQVTTGII
TLVYHVPILAALTHQVGAILILTTFLFIQNIVTNFELLH

Sequences:

>Translated_359_residues
MDKPHIQIMSIWLIVSTLLLLLMIVVGGITRLTNAGLSIVEWNPVSGIIPPISSEDWNNEFNKYTASPEFNLINNQITIS
EFKYIFFIEYIHRLLGRITGIIIIIPFLIFYYLKSLTKLQCYRLLLITCLVIIQGFMGWYMVKSGLKDTPYINHCRLAGH
LLLAVVIYHQLIAELLIIIQPFKCYMLATSKANNSNSTSINVINLKTKLIVLNKIIIFLLYTQIMFGALVAGLDAGLIYN
EFPNMGDSLIPIEILNQSIDFTMFDNQVLMQFIHRWFGILISCLIICYAIWLIILNKQALRGMGMVAACLVLVQVTTGII
TLVYHVPILAALTHQVGAILILTTFLFIQNIVTNFELLH
>Mature_359_residues
MDKPHIQIMSIWLIVSTLLLLLMIVVGGITRLTNAGLSIVEWNPVSGIIPPISSEDWNNEFNKYTASPEFNLINNQITIS
EFKYIFFIEYIHRLLGRITGIIIIIPFLIFYYLKSLTKLQCYRLLLITCLVIIQGFMGWYMVKSGLKDTPYINHCRLAGH
LLLAVVIYHQLIAELLIIIQPFKCYMLATSKANNSNSTSINVINLKTKLIVLNKIIIFLLYTQIMFGALVAGLDAGLIYN
EFPNMGDSLIPIEILNQSIDFTMFDNQVLMQFIHRWFGILISCLIICYAIWLIILNKQALRGMGMVAACLVLVQVTTGII
TLVYHVPILAALTHQVGAILILTTFLFIQNIVTNFELLH

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=357, Percent_Identity=34.453781512605, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI17921987, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17536069, Length=364, Percent_Identity=31.5934065934066, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320989, Length=372, Percent_Identity=34.6774193548387, Blast_Score=193, Evalue=4e-50,
Organism=Drosophila melanogaster, GI19922860, Length=353, Percent_Identity=35.1274787535411, Blast_Score=202, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 40741; Mature: 40741

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPHIQIMSIWLIVSTLLLLLMIVVGGITRLTNAGLSIVEWNPVSGIIPPISSEDWNNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCH
FNKYTASPEFNLINNQITISEFKYIFFIEYIHRLLGRITGIIIIIPFLIFYYLKSLTKLQ
HHCEECCCCCEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYRLLLITCLVIIQGFMGWYMVKSGLKDTPYINHCRLAGHLLLAVVIYHQLIAELLIIIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFKCYMLATSKANNSNSTSINVINLKTKLIVLNKIIIFLLYTQIMFGALVAGLDAGLIYN
CHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EFPNMGDSLIPIEILNQSIDFTMFDNQVLMQFIHRWFGILISCLIICYAIWLIILNKQAL
CCCCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMGMVAACLVLVQVTTGIITLVYHVPILAALTHQVGAILILTTFLFIQNIVTNFELLH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKPHIQIMSIWLIVSTLLLLLMIVVGGITRLTNAGLSIVEWNPVSGIIPPISSEDWNNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCH
FNKYTASPEFNLINNQITISEFKYIFFIEYIHRLLGRITGIIIIIPFLIFYYLKSLTKLQ
HHCEECCCCCEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYRLLLITCLVIIQGFMGWYMVKSGLKDTPYINHCRLAGHLLLAVVIYHQLIAELLIIIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFKCYMLATSKANNSNSTSINVINLKTKLIVLNKIIIFLLYTQIMFGALVAGLDAGLIYN
CHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EFPNMGDSLIPIEILNQSIDFTMFDNQVLMQFIHRWFGILISCLIICYAIWLIILNKQAL
CCCCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMGMVAACLVLVQVTTGIITLVYHVPILAALTHQVGAILILTTFLFIQNIVTNFELLH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA