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The map label for this gene is 189183589

Identifier: 189183589

GI number: 189183589

Start: 711665

End: 712237

Strand: Direct

Name: 189183589

Synonym: OTT_0682

Alternate gene names: NA

Gene position: 711665-712237 (Clockwise)

Preceding gene: 189183583

Following gene: 189183590

Centisome position: 35.42

GC content: 28.97

Gene sequence:

>573_bases
ATGCATCAAAATTATTATAAACAAACTCTACGTTCCAAATATAAGAATATACGAATCTTGGCAAATAAACAATTAAAAAG
TTGTTATCAACAAAGCCATCAAATATTGTTAAAAGCTGTATATATTCTTACTTCATTACTTCCTACTAATTCTGTAATTG
GTATTTATTATCCATTTAAAGGCGAAGTTAATGTATTAGATTTGTTAATGATAATGCCTAACTATAAATTTGCTCTACCA
GCTCTTATTGACAAACAAATGTTATATAGCTACTATTATATAGGTTGCCCAATCAAAAAACAAGAACATGAAATATATAC
TCCAGTTGGTACTGATATAGTGCTGCCATCTGCATTATTAGTTCCAGGTTTGGTGTTTGATGTTGCTGGTTATAGAATTG
GCTTTGGTAAAGGATATTATGATCAATACATATCGCAAGCCAGAAGTATTAATAGCAATAACATAGCAATTGGAGTATGT
TTTGATATACAGCTAAGAAACTTTGTACCTAGGGAGTTGCATGATCAAAAAATGGACTATATTATAACAAATAAAACATT
AATTGTAACATGA

Upstream 100 bases:

>100_bases
GGCAATAAACTATTATACATTATACTTAAAATAATTCTAAATTAAGCAATTACTGTGTTCAATAATGTTTTATTACTCAA
CATGTTAATATAACCTCAGT

Downstream 100 bases:

>100_bases
ATATAATAGATATAATTTCTCTTGTAATCTTTATTAGCGCAATTACCTTAGGGTTTTATAAAGGTGGGTTAAAATTGATT
ATTGGATCAATTTTTTTTGT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: 5-Formyltetrahydrofolate Cyclo-Ligase Family Protein; 5 10-Methenyltetrahydrofolate Synthetase; 5-Formyltetrahydrofolate Cyclo- Ligase; 5-Formyltetrahydrofolate Cyclo-Ligase Protein; Porphobilinogen Deaminase; 10-Methenyltetrahydrofolate Synthetase.

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCYQQSHQILLKAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMIMPNYKFALP
ALIDKQMLYSYYYIGCPIKKQEHEIYTPVGTDIVLPSALLVPGLVFDVAGYRIGFGKGYYDQYISQARSINSNNIAIGVC
FDIQLRNFVPRELHDQKMDYIITNKTLIVT

Sequences:

>Translated_190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCYQQSHQILLKAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMIMPNYKFALP
ALIDKQMLYSYYYIGCPIKKQEHEIYTPVGTDIVLPSALLVPGLVFDVAGYRIGFGKGYYDQYISQARSINSNNIAIGVC
FDIQLRNFVPRELHDQKMDYIITNKTLIVT
>Mature_190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCYQQSHQILLKAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMIMPNYKFALP
ALIDKQMLYSYYYIGCPIKKQEHEIYTPVGTDIVLPSALLVPGLVFDVAGYRIGFGKGYYDQYISQARSINSNNIAIGVC
FDIQLRNFVPRELHDQKMDYIITNKTLIVT

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.3.2

Molecular weight: Translated: 21949; Mature: 21949

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQNYYKQTLRSKYKNIRILANKQLKSCYQQSHQILLKAVYILTSLLPTNSVIGIYYPFK
CCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GEVNVLDLLMIMPNYKFALPALIDKQMLYSYYYIGCPIKKQEHEIYTPVGTDIVLPSALL
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCCCHHCCHHHH
VPGLVFDVAGYRIGFGKGYYDQYISQARSINSNNIAIGVCFDIQLRNFVPRELHDQKMDY
HHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCE
IITNKTLIVT
EEECCEEEEC
>Mature Secondary Structure
MHQNYYKQTLRSKYKNIRILANKQLKSCYQQSHQILLKAVYILTSLLPTNSVIGIYYPFK
CCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GEVNVLDLLMIMPNYKFALPALIDKQMLYSYYYIGCPIKKQEHEIYTPVGTDIVLPSALL
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCCCHHCCHHHH
VPGLVFDVAGYRIGFGKGYYDQYISQARSINSNNIAIGVCFDIQLRNFVPRELHDQKMDY
HHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCE
IITNKTLIVT
EEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA