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The map label for this gene is 189183560

Identifier: 189183560

GI number: 189183560

Start: 684528

End: 685319

Strand: Direct

Name: 189183560

Synonym: OTT_0653

Alternate gene names: NA

Gene position: 684528-685319 (Clockwise)

Preceding gene: 189183559

Following gene: 189183561

Centisome position: 34.07

GC content: 24.62

Gene sequence:

>792_bases
ATGAAATTTGTAAAATATATAACAGCTGTTTTATTATTAACACTGTTAAATACAACCATTGCAGCAAAACGAAACAACAA
TCAACCTGTACAACAGAAATTAATTCAGGATAAAGCTATATTAGCAGAAAAACATTTTAATGTTGGAATTTCATTTCTTG
AGTTAAACAAATATCAAGAAGCAATGAAAAATTTTGATTTAGCTATTAAGTACAAAGCTAATTATTCAGAAGCTTATGTT
AATAAAGGATTTTGTTTAGGTGAATTAGAACGATATAAAGAAGCAATAAAAAATTATAATTTAGCTATTAAGTACAAACA
TAATTTGGCAGAAGCTTATGTTAATAAAGGATTTTGTTTAGGTAAATTAAGACAATATCAAGAAGCAATAGAAAACTACG
ATTTAGCTATTAAGTATAATCCTAATCATGCAGATGCTTATTATAATAAAGGAAATTGTTTAGCTAAATTAGGACAATAT
CAAGAAGCAATAGAAAATTTTGATTTAGCTATTAAGTATAATCCTAATCATGCAGATGCTTATTACAATAAAGGAGTTTG
TTTATGTAAGTCAGGACAATTTCAAGAAGCGATAGAAAATTATGATTTGGCTATTAAATATAATCCTAATCATGCATATG
CTTATTATAATAAAGGAAATTGTTTAGCTAAATTAGGCCAATATCAAAAAGCAATAGAAAATTTTGATTTAGCTATTAAA
TATGATCCTAATAATGGAACATTATACAAGTTAATAAATATATTCAAACAAAATGCAGGTATTAAAAAGTAA

Upstream 100 bases:

>100_bases
AAAAAATATAAAAGAAAGAATAATTACAATACCTCTAATTCAGTAATTATTTGGTGTTCAGTAGAGCTAATCAAAAATTT
AAAGGGTAATTAATAATCAT

Downstream 100 bases:

>100_bases
TCTTGATTTTTAAATGATATCTGTAATAAGCAGGTATTATAAGGTATTATCATGATTTATTTGTGATACAAATTGTTATA
AAATAGTCATAAGATATAAT

Product: TPR repeat-containing protein 05

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKFVKYITAVLLLTLLNTTIAAKRNNNQPVQQKLIQDKAILAEKHFNVGISFLELNKYQEAMKNFDLAIKYKANYSEAYV
NKGFCLGELERYKEAIKNYNLAIKYKHNLAEAYVNKGFCLGKLRQYQEAIENYDLAIKYNPNHADAYYNKGNCLAKLGQY
QEAIENFDLAIKYNPNHADAYYNKGVCLCKSGQFQEAIENYDLAIKYNPNHAYAYYNKGNCLAKLGQYQKAIENFDLAIK
YDPNNGTLYKLINIFKQNAGIKK

Sequences:

>Translated_263_residues
MKFVKYITAVLLLTLLNTTIAAKRNNNQPVQQKLIQDKAILAEKHFNVGISFLELNKYQEAMKNFDLAIKYKANYSEAYV
NKGFCLGELERYKEAIKNYNLAIKYKHNLAEAYVNKGFCLGKLRQYQEAIENYDLAIKYNPNHADAYYNKGNCLAKLGQY
QEAIENFDLAIKYNPNHADAYYNKGVCLCKSGQFQEAIENYDLAIKYNPNHAYAYYNKGNCLAKLGQYQKAIENFDLAIK
YDPNNGTLYKLINIFKQNAGIKK
>Mature_263_residues
MKFVKYITAVLLLTLLNTTIAAKRNNNQPVQQKLIQDKAILAEKHFNVGISFLELNKYQEAMKNFDLAIKYKANYSEAYV
NKGFCLGELERYKEAIKNYNLAIKYKHNLAEAYVNKGFCLGKLRQYQEAIENYDLAIKYNPNHADAYYNKGNCLAKLGQY
QEAIENFDLAIKYNPNHADAYYNKGVCLCKSGQFQEAIENYDLAIKYNPNHAYAYYNKGNCLAKLGQYQKAIENFDLAIK
YDPNNGTLYKLINIFKQNAGIKK

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=230, Percent_Identity=28.695652173913, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI32307150, Length=230, Percent_Identity=28.695652173913, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI301336134, Length=239, Percent_Identity=29.2887029288703, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI118766330, Length=248, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI118766328, Length=248, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI310110582, Length=195, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI310131789, Length=195, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI310123097, Length=195, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI224809432, Length=193, Percent_Identity=29.0155440414508, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83415184, Length=241, Percent_Identity=29.4605809128631, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI296531396, Length=213, Percent_Identity=26.2910798122066, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI170784867, Length=192, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI22749211, Length=217, Percent_Identity=28.110599078341, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI167466177, Length=222, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI167466175, Length=222, Percent_Identity=25.6756756756757, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=191, Percent_Identity=28.7958115183246, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=183, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563052, Length=148, Percent_Identity=26.3513513513513, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147174, Length=220, Percent_Identity=25, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319387, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17647755, Length=183, Percent_Identity=31.1475409836066, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585827, Length=183, Percent_Identity=31.1475409836066, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585829, Length=183, Percent_Identity=31.1475409836066, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656717, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18110006, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647123, Length=208, Percent_Identity=27.4038461538462, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076610, Length=186, Percent_Identity=29.5698924731183, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920486, Length=186, Percent_Identity=29.5698924731183, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137540, Length=207, Percent_Identity=25.6038647342995, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 30313; Mature: 30313

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVKYITAVLLLTLLNTTIAAKRNNNQPVQQKLIQDKAILAEKHFNVGISFLELNKYQE
CHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
AMKNFDLAIKYKANYSEAYVNKGFCLGELERYKEAIKNYNLAIKYKHNLAEAYVNKGFCL
HHHCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCHH
GKLRQYQEAIENYDLAIKYNPNHADAYYNKGNCLAKLGQYQEAIENFDLAIKYNPNHADA
HHHHHHHHHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCH
YYNKGVCLCKSGQFQEAIENYDLAIKYNPNHAYAYYNKGNCLAKLGQYQKAIENFDLAIK
HHCCCEEEECCCCHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEE
YDPNNGTLYKLINIFKQNAGIKK
EECCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFVKYITAVLLLTLLNTTIAAKRNNNQPVQQKLIQDKAILAEKHFNVGISFLELNKYQE
CHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
AMKNFDLAIKYKANYSEAYVNKGFCLGELERYKEAIKNYNLAIKYKHNLAEAYVNKGFCL
HHHCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCHH
GKLRQYQEAIENYDLAIKYNPNHADAYYNKGNCLAKLGQYQEAIENFDLAIKYNPNHADA
HHHHHHHHHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCH
YYNKGVCLCKSGQFQEAIENYDLAIKYNPNHAYAYYNKGNCLAKLGQYQKAIENFDLAIK
HHCCCEEEECCCCHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEE
YDPNNGTLYKLINIFKQNAGIKK
EECCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]