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The map label for this gene is infC

Identifier: 189026074

GI number: 189026074

Start: 921187

End: 921726

Strand: Reverse

Name: infC

Synonym: TPASS_0850

Alternate gene names: 189026074

Gene position: 921726-921187 (Counterclockwise)

Preceding gene: 189026076

Following gene: 189026073

Centisome position: 80.89

GC content: 51.48

Gene sequence:

>540_bases
ATGTACTGGGGAGGATCGTTGGCGGATAACAAAAGCTTGCGGATTAATGGAAGTATTCGGGTACGAGAAGTGAGGTTGGT
TGACGCTGTAGGGCAGCAGTGTGGGGTGGTGCCCACCCCTGAGGCGCTGAGAATGGCACGGGATATCAATCTTGATTTAG
TAGAGGTCGCTCCGCAGGCGAGTCCGCCGGTGTGCAAGATCCTGGACTATGGGAAGTATCGCTTTGAGATGGGCAAAAAG
TTGCGTGACTCGAAAAAGCGACAGAGATTGCAGACGCTCAAGGAGGTGCGTATGCAACCGAAGATCAACGACCATGACAT
GGCGTTTAAGGCCAAGCATATACAGCGGTTTCTCGATGAAGGGGATAAGGTGAAAGTGACTATCCGCTTTCGTGGAAGGG
AGCTTGCGCATACCGATCTGGGTTTTAACGTGTTACAGAATGTGCTTGGCCGTCTGGTGTGTGGGTATAGTGTTGAGAAG
CAGGCAGCAATGGAAGGTCGGTCTATGTCCATGACGCTCACTCCGAAGTCAAAGAAATGA

Upstream 100 bases:

>100_bases
GTGATGGGGATGGTGATTTCCTGCATGTTTACTTGACATGACATATTAGGAATGGCTAGATTGGGGCCCAGTCTTGTTTT
TTAGCGTGCATTAGAAGTGG

Downstream 100 bases:

>100_bases
TGGAGTGTCGGGTAACTGCAGTTCGTGTTGTTGGATAAAGGGGAGAAAGTATATGGCTAAGATGAAAACGAAAAGCGCAG
CAGCAAAGCGTTTTAGTGTA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MYWGGSLADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQASPPVCKILDYGKYRFEMGKK
LRDSKKRQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDEGDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEK
QAAMEGRSMSMTLTPKSKK

Sequences:

>Translated_179_residues
MYWGGSLADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQASPPVCKILDYGKYRFEMGKK
LRDSKKRQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDEGDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEK
QAAMEGRSMSMTLTPKSKK
>Mature_179_residues
MYWGGSLADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQASPPVCKILDYGKYRFEMGKK
LRDSKKRQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDEGDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEK
QAAMEGRSMSMTLTPKSKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=180, Percent_Identity=43.3333333333333, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_TREPA (O83822)

Other databases:

- EMBL:   AE000520
- PIR:   B71274
- RefSeq:   NP_219286.1
- ProteinModelPortal:   O83822
- SMR:   O83822
- IntAct:   O83822
- GeneID:   2611030
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0850
- NMPDR:   fig|243276.1.peg.845
- TIGR:   TP_0850
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   TPAL243276:TP_0850-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20359; Mature: 20359

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWGGSLADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQA
CCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCC
SPPVCKILDYGKYRFEMGKKLRDSKKRQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDE
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
GDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEKQAAMEGRSMSMTLTPKSKK
CCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MYWGGSLADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQA
CCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCC
SPPVCKILDYGKYRFEMGKKLRDSKKRQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDE
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
GDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEKQAAMEGRSMSMTLTPKSKK
CCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876