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The map label for this gene is argS

Identifier: 189026055

GI number: 189026055

Start: 898927

End: 900696

Strand: Reverse

Name: argS

Synonym: TPASS_0831

Alternate gene names: 189026055

Gene position: 900696-898927 (Counterclockwise)

Preceding gene: 189026056

Following gene: 189026047

Centisome position: 79.05

GC content: 50.17

Gene sequence:

>1770_bases
GTGCAGGATCTGTGTGAGATGTGGCGGCACGCCGTCGCCCGGGTGCTTTCTCAACTGCAGGGGCCTGCCGTTGAGCCGGT
CGAAGGTGCGCAGTTAGTTATGGAAGAGCCGCCGGAGCCGGGTATGGGGGACATAGCTTTTCCTCTATTCCTTTTTGCAA
AGCGTGTGCGCAGGAGTCCTGCACAGCTTGCACAGCAGTTGTGCACACTGCTTGAAGAAGACACGTCCATGTGTGCGTAT
GGCACGCCGCAGGCGCGAGGACCCTATCTTAATGTCTTTTTAAATAAGGAGTGTGTAGCTGCGCATACGCTTGATGCTAT
CTTTGCGCAGGGGGAGCGCTATGGCCACACGCAGTACTTACAGGGCAAACGTATCATGGTTGAGTTCTCTAGTCCCAATA
CTAACAAGCCGTTGCATGTAGGTCATCTGCGCAATAACGCGATTGGGGAAAGCCTTTCGCGTATTATTGCGTTCTGTGGT
GCGGATGTGTTCAAGGTAAATATCATCAATGATCGCGGAGTACATATCTGTAAATCTATGTGCGCGTATCAAAAATTCGC
CCATGGAAAAACACCTGCGCATACCGGCATCAAGTCCGATCGCTTTGTGGGAGATTGGTACGTGCAGTTTAACCGTTACG
CACAGCAGTACCCGGAAGAAGCAGAGCACGATGTGCGTGACCTGTTACAGCGCTGGGAAAGTGCAGATCCGCACGTGCGT
GCGCTGTGGAGAACAATGAACGAATGGGCGTTGCGCGGTATCAAACAAACATATGAGCGAACGGGCATATCTTTTGATAA
ACTTTATTTTGAAAGCGAAACTTATACCAAGGGACGTGAAGAGGTTAGACGTGGTTTGGCCTGCGGCGTTTTTTATCAGA
TGGAGGACAACTCTATTTGGGTGGATTTGTCTTCTCTAGGCTTAGACAAAAAGGCGTTGCTTCGCTCTGACGGCACCACT
ATGTACATTACGCAGGATATTGGCACGGCGATTTTTCGCGCACAGGACTGGCCCTTTGATCAATTGCTGTATGTTGTGGG
AAACGAGCAGAACTACCACTTTAAGGTATTGTTCTTTGTGCTTAGGTTGCTCGGTTATCCGTGGGCGCAGCAGTTGCATC
ACGTCTCTTATGGCATGGTCAACTTGCCCCATGGGCGTATGAAGAGTCGAGAGGGGACGGTAGTAGATGCAGACGATATC
TTGGATCGTCTGCACAGTGCGGCAGAAGAGGAAATTGCAAAAAAGGGACGGGAAAATGCACTGAAACACGCACAGTGTAT
TGCAGAGAATGTTGCCATCGCCGCGCTTCATTATTTTTTATTGCAAGTCAGTCCTCAAAAGGATATGGTGTTTCACCCCG
AAGAGTCTTTGTCTTTTAACGGAAACACTGGTCCCTATTTACAGTATATGGGTGCTCGCATCTCTTCTCTTTTAAAGAAG
GTTCAGGAAGATGTGGAGCAAAAGGGACCTCGTGAAGTCCGGTGTGACCCTGCATTGCTCACGCACGAAGCTGAGTGGGA
GTTGGTGAAGGCGCTTGCACGTTTCCCTGCGTGTGTCACGCGCGCTGCACAGGGACATGATCCGAGCGTTATTACCGGGT
ATCTCTATACACTCTCAAAAAGCTTCAGTCGCTTCTATCATGATTGTCCCATTCTGTGTGAAGCACGACCGGACTACGCG
TGTGCAAGGCTTGAACTTGTGCGTGCGGTGCGCATAGTGCTGAGAACAGCTATGCGTCTGGTGCTGATTCCTTTTCTTGA
AGAGATGTAA

Upstream 100 bases:

>100_bases
ATTGAAGGACGGCGTACCGAATATCTCGGTTCAGAGGGAGTGTGGATCGGTGCACCGGTTTCTAAGAGTTCGTTCTAATA
GCTTGGTATGAGGTGAGGCA

Downstream 100 bases:

>100_bases
CGTGCATGCTTAATACGTCTTCCACCTTGCATTGCCTGTGGATGCCAGTTCACGTGCGAGGGTGTTCCTATTCTGCACGG
AGTAAGTGTTCGGGGTAACG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSPAQLAQQLCTLLEEDTSMCAY
GTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYLQGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCG
ADVFKVNIINDRGVHICKSMCAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIWVDLSSLGLDKKALLRSDGTT
MYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFVLRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDI
LDRLHSAAEEEIAKKGRENALKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKK
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSKSFSRFYHDCPILCEARPDYA
CARLELVRAVRIVLRTAMRLVLIPFLEEM

Sequences:

>Translated_589_residues
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSPAQLAQQLCTLLEEDTSMCAY
GTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYLQGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCG
ADVFKVNIINDRGVHICKSMCAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIWVDLSSLGLDKKALLRSDGTT
MYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFVLRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDI
LDRLHSAAEEEIAKKGRENALKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKK
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSKSFSRFYHDCPILCEARPDYA
CARLELVRAVRIVLRTAMRLVLIPFLEEM
>Mature_589_residues
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSPAQLAQQLCTLLEEDTSMCAY
GTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYLQGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCG
ADVFKVNIINDRGVHICKSMCAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIWVDLSSLGLDKKALLRSDGTT
MYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFVLRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDI
LDRLHSAAEEEIAKKGRENALKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKK
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSKSFSRFYHDCPILCEARPDYA
CARLELVRAVRIVLRTAMRLVLIPFLEEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=527, Percent_Identity=29.4117647058824, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI15149476, Length=560, Percent_Identity=25.1785714285714, Blast_Score=172, Evalue=1e-42,
Organism=Escherichia coli, GI1788184, Length=556, Percent_Identity=26.978417266187, Blast_Score=185, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71985061, Length=581, Percent_Identity=25.9896729776248, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71985068, Length=549, Percent_Identity=26.0473588342441, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17532153, Length=500, Percent_Identity=23.2, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=523, Percent_Identity=28.6806883365201, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321883, Length=590, Percent_Identity=27.7966101694915, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28571570, Length=486, Percent_Identity=27.7777777777778, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI18859963, Length=489, Percent_Identity=26.3803680981595, Blast_Score=143, Evalue=4e-34,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_TREPA (O83803)

Other databases:

- EMBL:   AE000520
- PIR:   A71277
- RefSeq:   NP_219267.1
- ProteinModelPortal:   O83803
- IntAct:   O83803
- GeneID:   2610958
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0831
- NMPDR:   fig|243276.1.peg.826
- TIGR:   TP_0831
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- ProtClustDB:   PRK01611
- BioCyc:   TPAL243276:TP_0831-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 67133; Mature: 67133

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCH
AQLAQQLCTLLEEDTSMCAYGTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYL
HHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHC
QGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCGADVFKVNIINDRGVHICKSM
CCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
CAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIW
HHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHCCCHHHHHCCCCEEEEEEEECCEEE
VDLSSLGLDKKALLRSDGTTMYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFV
EEHHHCCCCHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHEEEEEECCCCCCHHHHHHH
LRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDILDRLHSAAEEEIAKKGRENA
HHHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSK
HHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SFSRFYHDCPILCEARPDYACARLELVRAVRIVLRTAMRLVLIPFLEEM
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCH
AQLAQQLCTLLEEDTSMCAYGTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYL
HHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHC
QGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCGADVFKVNIINDRGVHICKSM
CCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
CAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIW
HHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHCCCHHHHHCCCCEEEEEEEECCEEE
VDLSSLGLDKKALLRSDGTTMYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFV
EEHHHCCCCHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHEEEEEECCCCCCHHHHHHH
LRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDILDRLHSAAEEEIAKKGRENA
HHHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSK
HHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SFSRFYHDCPILCEARPDYACARLELVRAVRIVLRTAMRLVLIPFLEEM
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876