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The map label for this gene is yaeL [C]

Identifier: 189025826

GI number: 189025826

Start: 653025

End: 654377

Strand: Reverse

Name: yaeL [C]

Synonym: TPASS_0600

Alternate gene names: 189025826

Gene position: 654377-653025 (Counterclockwise)

Preceding gene: 189025827

Following gene: 189025825

Centisome position: 57.43

GC content: 48.26

Gene sequence:

>1353_bases
GTGATTAAGATAATTATTGGCGTTGTGGTGCTTGGTATTGTGGTGTTGTTTCATGAACTGGGGCATTTTGTCGCCGCGCT
TTGGTGTCGAGTGGAGGTGCTCAGTTTTTCTGTCGGTATGGGGCCGGTCCTGTTTCGAAAGAAATTTGGAAAAACGGAAT
ATCGCCTTTCGATGCTTCCTCTTGGGGGGTATTGCGGTATGAAGGGAGAGCAAGCGTTTCAAACGGCGCTTGATCAAAAA
CTTTCCCGTATTCCCGTTGAGCCCGGTTCACTGTATGCAGTAGGACCGCTCAAACGCATGGGTATTGCCTTTGCAGGACC
GCTGGCGAATGTGCTTATGGCGGTAATGGTATTGGCATTGGTTAGTGCGCTTGGCTCGCGTGTACACACATTTGGAAACC
GTATTTCACCGGTGTATGTATACGATAGTTCTGATAACTCGCCTGCACGCCGCGTGGGACTTCAGGACGGGGATACAATC
CTGCGCATTGGTGACCAGCCGATACGCTATTTCAGTGATATTCAAAAAATTGTATCACAGCATGCGCAGCGTGCATTGCC
ATTTGTGATCGAACGGAGGGGGCAGCTTATGCACGTGACCATTACGCCTGATAGAGATGCGCATACTGGCATGGGGAGGG
TTGGTATTTACCATTACGTACCGCTAGTTGTTGCGGCGGTTGATGCACACGGTGCTGCATCGCGGGCAGGTCTTGAACCT
GAAGATAAAATTCTTGCAGTAGCAGGACGCCGTGTGCAACACGCAGTACAGCTCCTTGCGCTGCTCAAGGAATTTCGAAA
AAAGTCAGTCGTATTGACTGTGCTGCGTTCAGGGAAGAGGCGATATCATACCATTGCGTTAGTGCGCACAGAAAACGGGG
CAATAGATGTTGGTATCGAATGGAAAGCTCACACCGTGGTTATACCGGGAACTTCTTTTTTTGCAAGTGTCCGTGCGGGC
ATTGCAGAAACGTTGCGTATGTGTGTATTGACGGTGAAGGGTATTGGTATGCTCTTTCGGGGCCTGCAATTTCAGCAGGC
TATCTCAGGCCCATTAAGGATTACGCATGTGATAGGAGATGTGGCCCAGCATGGTTTTCAGGAGAGTTTTTTAACGGGAC
TGTCACAATTATGCGAGTTTGTGGCACTCGTGTGCGTCTCTCTCTTTATTATGAATCTACTCCCCATTCCGATCCTGGAC
GGCGGTTTGATTTTATTCGCATGTGTTGAATTGTTTATGCAAAGAAGCATACACCCGCGTGTGTTGTACTATCTGCAGTT
TGTAGGTTTTGCGTTTGTTGCATTGATATTTTTATGTGCGTTTTGGAACGACGTGAATTTTTTGTTTCACTAG

Upstream 100 bases:

>100_bases
ATTGGCGCGCAATTCCCCAAACGTTTGAAGAAGTTATGGCGTGCGATACGCGTGCGCGGATGTGTGCGCGGACGTGCATT
GCACAGAGGTGGAGAGAGAG

Downstream 100 bases:

>100_bases
GAGTGAGTGATGCAGTTACGGTGTGCGTGTGAGCGGGTGTTCGATATTGAACATGAGACGGTAATTTCGCTTGATGAGCA
CCCGGAATTTGTTGCGCGTA

Product: zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLPLGGYCGMKGEQAFQTALDQK
LSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLALVSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTI
LRIGDQPIRYFSDIQKIVSQHAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEP
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIEWKAHTVVIPGTSFFASVRAG
IAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGDVAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILD
GGLILFACVELFMQRSIHPRVLYYLQFVGFAFVALIFLCAFWNDVNFLFH

Sequences:

>Translated_450_residues
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLPLGGYCGMKGEQAFQTALDQK
LSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLALVSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTI
LRIGDQPIRYFSDIQKIVSQHAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEP
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIEWKAHTVVIPGTSFFASVRAG
IAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGDVAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILD
GGLILFACVELFMQRSIHPRVLYYLQFVGFAFVALIFLCAFWNDVNFLFH
>Mature_450_residues
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLPLGGYCGMKGEQAFQTALDQK
LSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLALVSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTI
LRIGDQPIRYFSDIQKIVSQHAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEP
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIEWKAHTVVIPGTSFFASVRAG
IAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGDVAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILD
GGLILFACVELFMQRSIHPRVLYYLQFVGFAFVALIFLCAFWNDVNFLFH

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=462, Percent_Identity=29.2207792207792, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y600_TREPA (O83609)

Other databases:

- EMBL:   AE000520
- PIR:   B71304
- RefSeq:   NP_219038.1
- ProteinModelPortal:   O83609
- SMR:   O83609
- IntAct:   O83609
- MEROPS:   M50.004
- GeneID:   2611523
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0600
- NMPDR:   fig|243276.1.peg.597
- TIGR:   TP_0600
- HOGENOM:   HBG732063
- OMA:   GMIDESM
- ProtClustDB:   CLSK218780
- BioCyc:   TPAL243276:TP_0600-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 49566; Mature: 49566

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 19-19

Signals:

None

Transmembrane regions:

HASH(0x20a2e574)-; HASH(0x21378798)-; HASH(0x213cbfe4)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEE
LGGYCGMKGEQAFQTALDQKLSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLAL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTILRIGDQPIRYFSDIQKIVSQ
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
HAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEP
HHHHHCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCC
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEEE
WKAHTVVIPGTSFFASVRAGIAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGD
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILDGGLILFACVELFMQRSIHPR
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHH
VLYYLQFVGFAFVALIFLCAFWNDVNFLFH
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCH
>Mature Secondary Structure
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEE
LGGYCGMKGEQAFQTALDQKLSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLAL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTILRIGDQPIRYFSDIQKIVSQ
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
HAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEP
HHHHHCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCC
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEEE
WKAHTVVIPGTSFFASVRAGIAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGD
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILDGGLILFACVELFMQRSIHPR
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHH
VLYYLQFVGFAFVALIFLCAFWNDVNFLFH
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876