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The map label for this gene is atoD [H]

Identifier: 188586524

GI number: 188586524

Start: 2004646

End: 2005302

Strand: Reverse

Name: atoD [H]

Synonym: Nther_1910

Alternate gene names: 188586524

Gene position: 2005302-2004646 (Counterclockwise)

Preceding gene: 188586525

Following gene: 188586523

Centisome position: 63.35

GC content: 40.49

Gene sequence:

>657_bases
ATGATAGAAATACTGTCTGCAAAAGAAAGTGTCAAGCAAATTACAGACGGATCCACCGTAATGGTGGGTGGCTTTCTTGC
AACCGGAACTCCGGAAACATTGGTTGATGCTCTACAAGAACAAGGAACAGGAAAATTGACTTTAGTAGCAAATGATACTT
CTTTTCCCGAAAAAGGAATCGGTAAACTAATAGTTTCTAATCAGTTTGAAAAGGTCATAGTTTCTCATATTGGCACCAAC
AAGTATACCGGGGAAAAAATGAATAATGGAGAACTTGAAGTTGACCTGGTGCCTCAGGGAACACTAGCGGAACAAGTCCG
CGCAGCTGGTGCAGGACTTGGGGGTATTCTAACACCTACTGGAATTGGTACTGTTGCCGAAGAAGGTAAGCAAAAGCTAA
CAGTTGATGAAAAAGAGTATATTTTAGCAGAACCTATAGAAGGTGATGTGGCTTTAATCAAAGCAGAAAAAGCTGATAAA
AATGGTAACTTGGTTTATAGACTTTCTGCACGTAATTTTAATCCTCTTATGGCTAAAGCTGCTAAAGTCGTGATAGCCGA
AGTTGGAGAAATAGTAGAACCAGGTGAATTAGATCCAGACGAAGTTATAACTCCCGGTGTCTATGTTGACTATCTTGTGA
GAAGGGAGGAGGGATAA

Upstream 100 bases:

>100_bases
ACTTGTAAAGTGATTAGAGAGTTGGCATGAATGTTGCATAAGTATATAATTACCTCGATTTATAAATAAATTTTGATTTA
CCACTATGGGAGGTGAAATT

Downstream 100 bases:

>100_bases
CTATGGATAAAAAAGAAAAAAGAAATTTAATAGCTAAGCGTATAGCTCAAGAAATACAACCAGGAGAAGTGGTTAACCTA
GGAATAGGAATGCCTACCTT

Product: butyryl-CoA:acetoacetate CoA-transferase alpha subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIEILSAKESVKQITDGSTVMVGGFLATGTPETLVDALQEQGTGKLTLVANDTSFPEKGIGKLIVSNQFEKVIVSHIGTN
KYTGEKMNNGELEVDLVPQGTLAEQVRAAGAGLGGILTPTGIGTVAEEGKQKLTVDEKEYILAEPIEGDVALIKAEKADK
NGNLVYRLSARNFNPLMAKAAKVVIAEVGEIVEPGELDPDEVITPGVYVDYLVRREEG

Sequences:

>Translated_218_residues
MIEILSAKESVKQITDGSTVMVGGFLATGTPETLVDALQEQGTGKLTLVANDTSFPEKGIGKLIVSNQFEKVIVSHIGTN
KYTGEKMNNGELEVDLVPQGTLAEQVRAAGAGLGGILTPTGIGTVAEEGKQKLTVDEKEYILAEPIEGDVALIKAEKADK
NGNLVYRLSARNFNPLMAKAAKVVIAEVGEIVEPGELDPDEVITPGVYVDYLVRREEG
>Mature_218_residues
MIEILSAKESVKQITDGSTVMVGGFLATGTPETLVDALQEQGTGKLTLVANDTSFPEKGIGKLIVSNQFEKVIVSHIGTN
KYTGEKMNNGELEVDLVPQGTLAEQVRAAGAGLGGILTPTGIGTVAEEGKQKLTVDEKEYILAEPIEGDVALIKAEKADK
NGNLVYRLSARNFNPLMAKAAKVVIAEVGEIVEPGELDPDEVITPGVYVDYLVRREEG

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=227, Percent_Identity=42.2907488986784, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=40.625, Blast_Score=156, Evalue=1e-38,
Organism=Escherichia coli, GI1788551, Length=215, Percent_Identity=54.4186046511628, Blast_Score=248, Evalue=2e-67,
Organism=Escherichia coli, GI1787985, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531517, Length=228, Percent_Identity=42.5438596491228, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24655794, Length=227, Percent_Identity=40.9691629955947, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21358325, Length=227, Percent_Identity=40.9691629955947, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23138; Mature: 23138

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEILSAKESVKQITDGSTVMVGGFLATGTPETLVDALQEQGTGKLTLVANDTSFPEKGI
CEEEECHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GKLIVSNQFEKVIVSHIGTNKYTGEKMNNGELEVDLVPQGTLAEQVRAAGAGLGGILTPT
HHEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
GIGTVAEEGKQKLTVDEKEYILAEPIEGDVALIKAEKADKNGNLVYRLSARNFNPLMAKA
CCCHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHH
AKVVIAEVGEIVEPGELDPDEVITPGVYVDYLVRREEG
HHHHHHHHHHHCCCCCCCHHHEECCCHHEEEEEEECCC
>Mature Secondary Structure
MIEILSAKESVKQITDGSTVMVGGFLATGTPETLVDALQEQGTGKLTLVANDTSFPEKGI
CEEEECHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GKLIVSNQFEKVIVSHIGTNKYTGEKMNNGELEVDLVPQGTLAEQVRAAGAGLGGILTPT
HHEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
GIGTVAEEGKQKLTVDEKEYILAEPIEGDVALIKAEKADKNGNLVYRLSARNFNPLMAKA
CCCHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHH
AKVVIAEVGEIVEPGELDPDEVITPGVYVDYLVRREEG
HHHHHHHHHHHCCCCCCCHHHEECCCHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]