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The map label for this gene is algU [H]

Identifier: 188586508

GI number: 188586508

Start: 1986465

End: 1987085

Strand: Reverse

Name: algU [H]

Synonym: Nther_1894

Alternate gene names: 188586508

Gene position: 1987085-1986465 (Counterclockwise)

Preceding gene: 188586509

Following gene: 188586507

Centisome position: 62.77

GC content: 35.27

Gene sequence:

>621_bases
GTGACAATTATGAAATCTAATGATGAGTTCTTGGTAAAACAATGTCAAAATGGTCATTTAGATGCTTTTGAAGAGCTAGT
ACATAAATATCACCAAAAGGTTTATTCACTGTGCTATAGGTTTTCAGGAAATCACGATGATGCTAATGACCTGGCACAAG
AAGCTTTTATTCGGGTTTATCATTCCATAAACAAATTTCATTTTAAATCCGCATTTTCAACCTGGTTGTACCGAGTCACT
TCTAATGTGTGTCTTGATGAAATGAGAAAACGGAAACGTAAATCTTCAGTATCTTTAGATTCGCCTATGGAAACTGATGA
TGGGGAATTGTATTTTAATTTACCTGATCAAAAATTCAATCCGGAATTAATGGCAGAGCGTAAGGACGTTCAAGAAATTG
TACACAAAGCTATTCAAGAACTACCAAAAGATCAAAAGTTAACATTGCTTTTACGAGAAATGGAAGGTTTTTCATATGAC
GAAATGGCAGAGGTGATGAATGTTTCCGTGGGAACTGTCAAGTCGCGTTTGAGTAGGGCTAGAAACAATTTAAAGGAAAT
CTTAGTCCAAAAAACGGAACTTTTTCCAGATAAATCACATCTAAAGGGTAAGGAGGTGTAA

Upstream 100 bases:

>100_bases
CTTAATAACGGTTTAATTTAAAACCCCTATATCTTAACTGTCAGGGGTGGTAAACCCGACAATTTTATAATAGAGTATAT
ATATGAAGAGGGTAAAGGAA

Downstream 100 bases:

>100_bases
CAGACAATGAATTGCAGTTGGATAATAGAGCGGCTTTCAAGTTACTTGGATGATCAACTTTGCCCTTTAGATGTGAAAAA
AGTTGAAAAACATTTGAAAA

Product: RNA polymerase, sigma-24 subunit, ECF subfamily

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTIMKSNDEFLVKQCQNGHLDAFEELVHKYHQKVYSLCYRFSGNHDDANDLAQEAFIRVYHSINKFHFKSAFSTWLYRVT
SNVCLDEMRKRKRKSSVSLDSPMETDDGELYFNLPDQKFNPELMAERKDVQEIVHKAIQELPKDQKLTLLLREMEGFSYD
EMAEVMNVSVGTVKSRLSRARNNLKEILVQKTELFPDKSHLKGKEV

Sequences:

>Translated_206_residues
MTIMKSNDEFLVKQCQNGHLDAFEELVHKYHQKVYSLCYRFSGNHDDANDLAQEAFIRVYHSINKFHFKSAFSTWLYRVT
SNVCLDEMRKRKRKSSVSLDSPMETDDGELYFNLPDQKFNPELMAERKDVQEIVHKAIQELPKDQKLTLLLREMEGFSYD
EMAEVMNVSVGTVKSRLSRARNNLKEILVQKTELFPDKSHLKGKEV
>Mature_205_residues
TIMKSNDEFLVKQCQNGHLDAFEELVHKYHQKVYSLCYRFSGNHDDANDLAQEAFIRVYHSINKFHFKSAFSTWLYRVTS
NVCLDEMRKRKRKSSVSLDSPMETDDGELYFNLPDQKFNPELMAERKDVQEIVHKAIQELPKDQKLTLLLREMEGFSYDE
MAEVMNVSVGTVKSRLSRARNNLKEILVQKTELFPDKSHLKGKEV

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=178, Percent_Identity=36.5168539325843, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24158; Mature: 24027

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIMKSNDEFLVKQCQNGHLDAFEELVHKYHQKVYSLCYRFSGNHDDANDLAQEAFIRVY
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HSINKFHFKSAFSTWLYRVTSNVCLDEMRKRKRKSSVSLDSPMETDDGELYFNLPDQKFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCC
PELMAERKDVQEIVHKAIQELPKDQKLTLLLREMEGFSYDEMAEVMNVSVGTVKSRLSRA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RNNLKEILVQKTELFPDKSHLKGKEV
HHHHHHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
TIMKSNDEFLVKQCQNGHLDAFEELVHKYHQKVYSLCYRFSGNHDDANDLAQEAFIRVY
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HSINKFHFKSAFSTWLYRVTSNVCLDEMRKRKRKSSVSLDSPMETDDGELYFNLPDQKFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCC
PELMAERKDVQEIVHKAIQELPKDQKLTLLLREMEGFSYDEMAEVMNVSVGTVKSRLSRA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RNNLKEILVQKTELFPDKSHLKGKEV
HHHHHHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]