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The map label for this gene is etfA [H]

Identifier: 188586494

GI number: 188586494

Start: 1968203

End: 1969435

Strand: Reverse

Name: etfA [H]

Synonym: Nther_1879

Alternate gene names: 188586494

Gene position: 1969435-1968203 (Counterclockwise)

Preceding gene: 188586495

Following gene: 188586493

Centisome position: 62.21

GC content: 38.36

Gene sequence:

>1233_bases
ATGGGTGTTAAAATATTAACAGATAAATGTAAGGGTTGTGCTTTATGTGTAGATGCATGTCCCTTCGAAGCTATTGAGAT
GAAAGATGATATAGCTGTACTAAATGAAAGCTGTACAAACTGTGGTGCTTGTATAGAATCTTGTAAATTTGGTGCTATTA
TAAAAGAAGAAGAAGACACTACTCCAAGAGGTACTGTTAATATAGATGAATATAAGGGAGTTTGGGTCTTTGCTGAACAA
AGAGACGGCGAATTAATGCCCGTTACAATCGAACTACTAGGTGAAGGTAAAAGGATAGCAAAAGAAATAGGAGAAGAGCT
AAGTGCAGTTCTAATAGGGGACAATGTAGAAGACCTTACTAAAGAACTGTTTGCCTATGGTGCAGATAATGTATATCTTT
GCCAAGATGAACTATTAAAGAACTTCACAACAGATGGATATACAAAGGTTTTAACAAACATGATCAACGACTACAAACCA
GAAATCATCTTAATAGGAGCAACCCATATAGGAAGAGACTTAGCCCCTAGAGTGGCTTCAAGAGTCAACACAGGTCTAAC
AGCAGATTGCACTCAATTGGATATAGATAGTGAAGACAACAAATTGCTGCAAACAAGGCCAGCCTTTGGTGGAAATATAA
TGGCAACTATAATCTGCCCTGATCATAGGCCGCAAATGGCTACAGTAAGACCAGGTGTAATGCAAAAGGCAGAAAAAGAA
GACAGTCGTGAAGGAAAAGTAGTAAATGTAGAAGCAAACGTGACACATGATGATATCAATATTTCAGTCAAAGAGATCAA
AAAAGAGAAAAAAGCCGTAGTTAACCTAGAAGAGAGCGATATTATAGTATCTGGTGGTCGAGGCCTTGGAAATCAAGATG
GATTTAAAATGTTACAGGATTTAGCCGATAAATTAGGCGGAGTTGTAGGGGCCTCTAGGGCAACAGTAGATGCAGGCTGG
ATTGATAAAGACCATCAGGTTGGACAAACAGGTAAGACAGTAAGGCCTGGTTTATATATTGCGTGTGGAATATCTGGAGC
AATCCAGCATCTAGCAGGAATGGAAGGTTCAGAGTGCATTGTAGCAATAAATAATAACCCTGATGCACCAATCTTTAAAG
TTGCCGATTACGGCATAGTAGGGGATGTATATGAAGTAGTCCCTAAACTTATAGAAGCTTTAGATAATGAGGAAGAATTA
GAAGAAGCAGTTAAAGAAATTACGGCTGATTAA

Upstream 100 bases:

>100_bases
GAAGGAGAAATGATAGAAGGTTCACCTAGAGAACAGGCCAAGACTTTATTAGTAAAACTTAAAAGCAGAAATGTAATATA
ACGACAAGGGGGATTTAAGA

Downstream 100 bases:

>100_bases
AATTAAGTAAAGGTTGAACAATAGAGTAGAAGTTGTTTAAATAGTCCCGGCAAGTAGCCGGGGCTTATTTGTTTGCCCGG
CATGCCTGCCGCGCCGATGG

Product: Electron transfer flavoprotein alpha/beta-subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MGVKILTDKCKGCALCVDACPFEAIEMKDDIAVLNESCTNCGACIESCKFGAIIKEEEDTTPRGTVNIDEYKGVWVFAEQ
RDGELMPVTIELLGEGKRIAKEIGEELSAVLIGDNVEDLTKELFAYGADNVYLCQDELLKNFTTDGYTKVLTNMINDYKP
EIILIGATHIGRDLAPRVASRVNTGLTADCTQLDIDSEDNKLLQTRPAFGGNIMATIICPDHRPQMATVRPGVMQKAEKE
DSREGKVVNVEANVTHDDINISVKEIKKEKKAVVNLEESDIIVSGGRGLGNQDGFKMLQDLADKLGGVVGASRATVDAGW
IDKDHQVGQTGKTVRPGLYIACGISGAIQHLAGMEGSECIVAINNNPDAPIFKVADYGIVGDVYEVVPKLIEALDNEEEL
EEAVKEITAD

Sequences:

>Translated_410_residues
MGVKILTDKCKGCALCVDACPFEAIEMKDDIAVLNESCTNCGACIESCKFGAIIKEEEDTTPRGTVNIDEYKGVWVFAEQ
RDGELMPVTIELLGEGKRIAKEIGEELSAVLIGDNVEDLTKELFAYGADNVYLCQDELLKNFTTDGYTKVLTNMINDYKP
EIILIGATHIGRDLAPRVASRVNTGLTADCTQLDIDSEDNKLLQTRPAFGGNIMATIICPDHRPQMATVRPGVMQKAEKE
DSREGKVVNVEANVTHDDINISVKEIKKEKKAVVNLEESDIIVSGGRGLGNQDGFKMLQDLADKLGGVVGASRATVDAGW
IDKDHQVGQTGKTVRPGLYIACGISGAIQHLAGMEGSECIVAINNNPDAPIFKVADYGIVGDVYEVVPKLIEALDNEEEL
EEAVKEITAD
>Mature_409_residues
GVKILTDKCKGCALCVDACPFEAIEMKDDIAVLNESCTNCGACIESCKFGAIIKEEEDTTPRGTVNIDEYKGVWVFAEQR
DGELMPVTIELLGEGKRIAKEIGEELSAVLIGDNVEDLTKELFAYGADNVYLCQDELLKNFTTDGYTKVLTNMINDYKPE
IILIGATHIGRDLAPRVASRVNTGLTADCTQLDIDSEDNKLLQTRPAFGGNIMATIICPDHRPQMATVRPGVMQKAEKED
SREGKVVNVEANVTHDDINISVKEIKKEKKAVVNLEESDIIVSGGRGLGNQDGFKMLQDLADKLGGVVGASRATVDAGWI
DKDHQVGQTGKTVRPGLYIACGISGAIQHLAGMEGSECIVAINNNPDAPIFKVADYGIVGDVYEVVPKLIEALDNEEELE
EAVKEITAD

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=337, Percent_Identity=36.2017804154303, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI189181759, Length=272, Percent_Identity=40.0735294117647, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI1787990, Length=332, Percent_Identity=31.0240963855422, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786226, Length=331, Percent_Identity=26.2839879154079, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082157, Length=248, Percent_Identity=26.2096774193548, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=332, Percent_Identity=37.6506024096386, Blast_Score=198, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6325261, Length=299, Percent_Identity=33.7792642140468, Blast_Score=166, Evalue=6e-42,
Organism=Drosophila melanogaster, GI17136898, Length=320, Percent_Identity=37.8125, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24652801, Length=320, Percent_Identity=37.8125, Blast_Score=190, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 44382; Mature: 44251

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVKILTDKCKGCALCVDACPFEAIEMKDDIAVLNESCTNCGACIESCKFGAIIKEEEDT
CCCEEECCCCCCEEEEECCCCCCHHCCCCHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC
TPRGTVNIDEYKGVWVFAEQRDGELMPVTIELLGEGKRIAKEIGEELSAVLIGDNVEDLT
CCCCEEEECCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHEEEEECCCHHHHH
KELFAYGADNVYLCQDELLKNFTTDGYTKVLTNMINDYKPEIILIGATHIGRDLAPRVAS
HHHHHHCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECHHHCCHHHHHHHH
RVNTGLTADCTQLDIDSEDNKLLQTRPAFGGNIMATIICPDHRPQMATVRPGVMQKAEKE
HHCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHH
DSREGKVVNVEANVTHDDINISVKEIKKEKKAVVNLEESDIIVSGGRGLGNQDGFKMLQD
HCCCCCEEEEEECCEECCCCEEHHHHHHHHHHEEECCCCCEEEECCCCCCCCHHHHHHHH
LADKLGGVVGASRATVDAGWIDKDHQVGQTGKTVRPGLYIACGISGAIQHLAGMEGSECI
HHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEE
VAINNNPDAPIFKVADYGIVGDVYEVVPKLIEALDNEEELEEAVKEITAD
EEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVKILTDKCKGCALCVDACPFEAIEMKDDIAVLNESCTNCGACIESCKFGAIIKEEEDT
CCEEECCCCCCEEEEECCCCCCHHCCCCHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC
TPRGTVNIDEYKGVWVFAEQRDGELMPVTIELLGEGKRIAKEIGEELSAVLIGDNVEDLT
CCCCEEEECCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHEEEEECCCHHHHH
KELFAYGADNVYLCQDELLKNFTTDGYTKVLTNMINDYKPEIILIGATHIGRDLAPRVAS
HHHHHHCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECHHHCCHHHHHHHH
RVNTGLTADCTQLDIDSEDNKLLQTRPAFGGNIMATIICPDHRPQMATVRPGVMQKAEKE
HHCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHH
DSREGKVVNVEANVTHDDINISVKEIKKEKKAVVNLEESDIIVSGGRGLGNQDGFKMLQD
HCCCCCEEEEEECCEECCCCEEHHHHHHHHHHEEECCCCCEEEECCCCCCCCHHHHHHHH
LADKLGGVVGASRATVDAGWIDKDHQVGQTGKTVRPGLYIACGISGAIQHLAGMEGSECI
HHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEE
VAINNNPDAPIFKVADYGIVGDVYEVVPKLIEALDNEEELEEAVKEITAD
EEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA