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The map label for this gene is engD [H]

Identifier: 188586450

GI number: 188586450

Start: 1910780

End: 1911871

Strand: Reverse

Name: engD [H]

Synonym: Nther_1835

Alternate gene names: 188586450

Gene position: 1911871-1910780 (Counterclockwise)

Preceding gene: 188586451

Following gene: 188586449

Centisome position: 60.4

GC content: 36.9

Gene sequence:

>1092_bases
ATGCAAATAGGTATTGTAGGACTTCCCAATGTAGGAAAATCGACTCTCTTTAATGCAATTACTCAAGCAGGTGCTGATTC
GGCTAATTTTCCCTTTTGCACCATTGATCCGAATATAGGAGTTGTTGATGTACCCGATGGACGGCTTGAAAAATTAACAG
AACTTGTTAATCCTAAAAAGACCACTCCTACGGCAATTGAATTCGTCGATATTGCGGGGCTGGTAAAAGGCGCAAGTAAA
GGAGAGGGTTTAGGAAATCAATTTCTGTCTAATATCCGTGAAGTGGATGCCATTGTCCACGTAGTGAGATGTTTTGAATC
CCAGGACATAACTCATGTTGATGGTTCTATAGATCCCATTAGGGATATTGAAACTATAAACCTAGAATTAGTTTTTTCCG
ATTTAGAATTGGTTGAAAGGCGAATAGAAAAAACGGAGAAATTAATGAAATCTGGCGGTAAAGAGTATCAAAAAGAACAC
AATCTATTAAAACGTTTACAAGAAACTTTAAGTGAAGGACGTTCTGCAAGAAGTTTGACTTTTACTAACGAAGAAAAAGA
AATTTTGAAATCCATGCCTTTATTATCGACAAAACCAATTTTATACGTTGCCAATGTAGGAGAAGAAGATTTGATTGGAG
ATTCCAATGATTTAGTAAAACAAGTAGAGGAATATGCTCGGGAAGAAGGTTCGGAAGTAATCAAAGTTTGTGCTAGTATT
GAATCAGAGATAGCAGAACTAGATGATGATGAAAAAGACGAATTCTTGAATGAAATTGGCCTTGAAGAGCCAGGTTTAAA
TAGAGTTATTAAAGCTGGGTATAAATTGTTGGGTTTGATAACGTTTTTTACAGCGGGAGAAAAAGAAGTGAGAGCTTGGA
CGGTGAAAGAAGGGGCCACAGCACCACAGGCTGCTGGAAAAATCCATAGTGATTTAGAACGAGGATTTATTAGAGCAGAA
GTTATAACTTTTGATGATATTCTAAAATACGAAAGCTATGCAAAAGCAAGAGAAAATGGTGTCTTAAGACTAGAGGGTAA
AGACTATATAGTCAAGGACGGAGATGTGACCCACTTTAGGTTTAATGTATAG

Upstream 100 bases:

>100_bases
TGATATGGTGTTTTAAAAAAAATTTAAGAAATAATTGTCAAGATAGCCGAGCTCGGGTATAATATGTAACCGTGTGTATA
CTTGTAAGGAGGTAGAAATT

Downstream 100 bases:

>100_bases
TTTTTCACCTTGATTAAAAACAGATTAGTTACTGTTCATTAGAAGGGGGATTACCCCTTCTTTTTTTATTTTAATCTCAA
AAATCTTAAACTAATTAAAA

Product: GTP-binding protein YchF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQIGIVGLPNVGKSTLFNAITQAGADSANFPFCTIDPNIGVVDVPDGRLEKLTELVNPKKTTPTAIEFVDIAGLVKGASK
GEGLGNQFLSNIREVDAIVHVVRCFESQDITHVDGSIDPIRDIETINLELVFSDLELVERRIEKTEKLMKSGGKEYQKEH
NLLKRLQETLSEGRSARSLTFTNEEKEILKSMPLLSTKPILYVANVGEEDLIGDSNDLVKQVEEYAREEGSEVIKVCASI
ESEIAELDDDEKDEFLNEIGLEEPGLNRVIKAGYKLLGLITFFTAGEKEVRAWTVKEGATAPQAAGKIHSDLERGFIRAE
VITFDDILKYESYAKARENGVLRLEGKDYIVKDGDVTHFRFNV

Sequences:

>Translated_363_residues
MQIGIVGLPNVGKSTLFNAITQAGADSANFPFCTIDPNIGVVDVPDGRLEKLTELVNPKKTTPTAIEFVDIAGLVKGASK
GEGLGNQFLSNIREVDAIVHVVRCFESQDITHVDGSIDPIRDIETINLELVFSDLELVERRIEKTEKLMKSGGKEYQKEH
NLLKRLQETLSEGRSARSLTFTNEEKEILKSMPLLSTKPILYVANVGEEDLIGDSNDLVKQVEEYAREEGSEVIKVCASI
ESEIAELDDDEKDEFLNEIGLEEPGLNRVIKAGYKLLGLITFFTAGEKEVRAWTVKEGATAPQAAGKIHSDLERGFIRAE
VITFDDILKYESYAKARENGVLRLEGKDYIVKDGDVTHFRFNV
>Mature_363_residues
MQIGIVGLPNVGKSTLFNAITQAGADSANFPFCTIDPNIGVVDVPDGRLEKLTELVNPKKTTPTAIEFVDIAGLVKGASK
GEGLGNQFLSNIREVDAIVHVVRCFESQDITHVDGSIDPIRDIETINLELVFSDLELVERRIEKTEKLMKSGGKEYQKEH
NLLKRLQETLSEGRSARSLTFTNEEKEILKSMPLLSTKPILYVANVGEEDLIGDSNDLVKQVEEYAREEGSEVIKVCASI
ESEIAELDDDEKDEFLNEIGLEEPGLNRVIKAGYKLLGLITFFTAGEKEVRAWTVKEGATAPQAAGKIHSDLERGFIRAE
VITFDDILKYESYAKARENGVLRLEGKDYIVKDGDVTHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=367, Percent_Identity=43.3242506811989, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=35.3982300884956, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI24308117, Length=111, Percent_Identity=34.2342342342342, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=58.6776859504132, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789574, Length=159, Percent_Identity=30.188679245283, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=41.6438356164384, Blast_Score=310, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6319499, Length=371, Percent_Identity=41.5094339622642, Blast_Score=284, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=37.7308707124011, Blast_Score=246, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=41.6893732970027, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=41.6893732970027, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=41.6893732970027, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=38.9570552147239, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40246; Mature: 40246

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIGIVGLPNVGKSTLFNAITQAGADSANFPFCTIDPNIGVVDVPDGRLEKLTELVNPKK
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHCCCC
TTPTAIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVHVVRCFESQDITHVDGSIDPI
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RDIETINLELVFSDLELVERRIEKTEKLMKSGGKEYQKEHNLLKRLQETLSEGRSARSLT
CCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
FTNEEKEILKSMPLLSTKPILYVANVGEEDLIGDSNDLVKQVEEYAREEGSEVIKVCASI
ECCHHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESEIAELDDDEKDEFLNEIGLEEPGLNRVIKAGYKLLGLITFFTAGEKEVRAWTVKEGAT
HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCC
APQAAGKIHSDLERGFIRAEVITFDDILKYESYAKARENGVLRLEGKDYIVKDGDVTHFR
CCHHHHHHHHHHHHCHHHHEEEHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure
MQIGIVGLPNVGKSTLFNAITQAGADSANFPFCTIDPNIGVVDVPDGRLEKLTELVNPKK
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHCCCC
TTPTAIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVHVVRCFESQDITHVDGSIDPI
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RDIETINLELVFSDLELVERRIEKTEKLMKSGGKEYQKEHNLLKRLQETLSEGRSARSLT
CCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
FTNEEKEILKSMPLLSTKPILYVANVGEEDLIGDSNDLVKQVEEYAREEGSEVIKVCASI
ECCHHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESEIAELDDDEKDEFLNEIGLEEPGLNRVIKAGYKLLGLITFFTAGEKEVRAWTVKEGAT
HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCC
APQAAGKIHSDLERGFIRAEVITFDDILKYESYAKARENGVLRLEGKDYIVKDGDVTHFR
CCHHHHHHHHHHHHCHHHHEEEHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]