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The map label for this gene is yisQ [H]

Identifier: 188586224

GI number: 188586224

Start: 1684367

End: 1685758

Strand: Reverse

Name: yisQ [H]

Synonym: Nther_1607

Alternate gene names: 188586224

Gene position: 1685758-1684367 (Counterclockwise)

Preceding gene: 188586226

Following gene: 188586223

Centisome position: 53.25

GC content: 35.42

Gene sequence:

>1392_bases
ATGAGATTTGATTTAGGCGAACAAAAGAGAAGAAATTTAATCTTGGAAGGCAATCTATTAAAAGTACTTTGGTTTCTTTC
ATGGCCTGTAACTATCCAATTAGTAGTGAACAATGTTGTTAGAGTTACGGGTACTAAAATGGTAGGTGTCTTAGGGTCTG
ATGCAATTGCTGCAGTAGGAATTGCACAACAAGTCCTTATGGGTGTATCTGTACCAGCTATGGGGTTATCTATGAGTGCT
ACTGCAGTTGTTGCAAATTATTTCGGAGAAAAAAATTACACAGGAACTTTATATGCAATTGGACAAATTATATTAATAGC
TCTATTATTATCTGGTTTTACAACTTTTATCGGTTTAAAATACGGTGACAATATTTTATTATTACTCGGAGCAGAAGAAC
AATTATTACAATTAAGCCATAACTATTTAAAAATTTTGTTTGCAGCTTCCTTTGTTCTAATAACCAAGTTTCCACTTTGG
GGGATTTTTCAAGGATTAGGTGATACAAGGATTCCGATGAAAATGGATCTTTTTTCTAATGCTTTGAATGTATCAGGAAA
TTATACTTTTATTTTTGGCCTTGGTCCAATCCCTTCTCTGGGATTAACGGGTGCTGCAGTTGGTAGTGTATTGGCTGATG
CGGTTATACTTGTGAGAGCTATAGGAGAATTAGCCAAAAAAATCTCGGGATTAGTTCTCAGCTTTTATGATTTATTTAAG
ATACGTTTGGCAATTATGAAGAAAATAATTAAAATTGGTGTACCAGCTACTTTACATGGTTTTATTCAGATGAGTAGCAA
TATTTTACTTATCATGATGATGACTCGTATCCCGGGAGGTACTGATGTGGTGTCTGCATATTCAGTAGGAATGGTTGTAT
TTGGCTTAACTACATTTCCTGCAGCTTCAATAGCAACTGTAGCAGCTTCAATGGTAGGTGTTAATTTGGGGAATTCAGAT
CAAAACAGGGCTATCTCTAGTGGTTTTACCTGTGCAATTACCGGTGCAATGGTTATTACTTTCACAGCTATTCTTACACG
AGTTTTCGCACCTGAACTATTAAAGTTTTTCGTTAAAGATTTATCTGTAATTAAAATCGGTGACTCATTATTAAAAACAC
TTTCTCTTGTTATGCCTGTTCATGCTTTGGGAATTGTCTTTTCAAGAGGAATGCAAGGAGCCGGGGACGCAAAAACACCT
TTTATAATTGCTGCATTAACAGGAGTAGGAGCTAGAGTGCCTCTGGCATACATTTTTACTTTCAGTATGGGGATGCAAAG
TAAAGGTATTTGGTTAGCCATTGCAGTTACACAAGTTATCTCAGCTGTTATTCTGACTTATAAATTTAAAACTGTAGTGA
GGAAAAGAGCCGAAAATATTAAAAATTACTAG

Upstream 100 bases:

>100_bases
ATTATGGTTTTTAAATAAGTATAATATGGAAAATTAATAAATAATGATAGTTTTAGAAAGTGAGGAATTAGAAAAAATAG
GTTTAATGGGAGAGGCGTAA

Downstream 100 bases:

>100_bases
CATAAGTGGTATAATTTAACTTGAGATGTCATTGACATTTTTAATGATTATTGTATCAAGTGTTAAAAATTATGGAGGAG
AGATTTCTTTGCGTGTTGGT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MRFDLGEQKRRNLILEGNLLKVLWFLSWPVTIQLVVNNVVRVTGTKMVGVLGSDAIAAVGIAQQVLMGVSVPAMGLSMSA
TAVVANYFGEKNYTGTLYAIGQIILIALLLSGFTTFIGLKYGDNILLLLGAEEQLLQLSHNYLKILFAASFVLITKFPLW
GIFQGLGDTRIPMKMDLFSNALNVSGNYTFIFGLGPIPSLGLTGAAVGSVLADAVILVRAIGELAKKISGLVLSFYDLFK
IRLAIMKKIIKIGVPATLHGFIQMSSNILLIMMMTRIPGGTDVVSAYSVGMVVFGLTTFPAASIATVAASMVGVNLGNSD
QNRAISSGFTCAITGAMVITFTAILTRVFAPELLKFFVKDLSVIKIGDSLLKTLSLVMPVHALGIVFSRGMQGAGDAKTP
FIIAALTGVGARVPLAYIFTFSMGMQSKGIWLAIAVTQVISAVILTYKFKTVVRKRAENIKNY

Sequences:

>Translated_463_residues
MRFDLGEQKRRNLILEGNLLKVLWFLSWPVTIQLVVNNVVRVTGTKMVGVLGSDAIAAVGIAQQVLMGVSVPAMGLSMSA
TAVVANYFGEKNYTGTLYAIGQIILIALLLSGFTTFIGLKYGDNILLLLGAEEQLLQLSHNYLKILFAASFVLITKFPLW
GIFQGLGDTRIPMKMDLFSNALNVSGNYTFIFGLGPIPSLGLTGAAVGSVLADAVILVRAIGELAKKISGLVLSFYDLFK
IRLAIMKKIIKIGVPATLHGFIQMSSNILLIMMMTRIPGGTDVVSAYSVGMVVFGLTTFPAASIATVAASMVGVNLGNSD
QNRAISSGFTCAITGAMVITFTAILTRVFAPELLKFFVKDLSVIKIGDSLLKTLSLVMPVHALGIVFSRGMQGAGDAKTP
FIIAALTGVGARVPLAYIFTFSMGMQSKGIWLAIAVTQVISAVILTYKFKTVVRKRAENIKNY
>Mature_463_residues
MRFDLGEQKRRNLILEGNLLKVLWFLSWPVTIQLVVNNVVRVTGTKMVGVLGSDAIAAVGIAQQVLMGVSVPAMGLSMSA
TAVVANYFGEKNYTGTLYAIGQIILIALLLSGFTTFIGLKYGDNILLLLGAEEQLLQLSHNYLKILFAASFVLITKFPLW
GIFQGLGDTRIPMKMDLFSNALNVSGNYTFIFGLGPIPSLGLTGAAVGSVLADAVILVRAIGELAKKISGLVLSFYDLFK
IRLAIMKKIIKIGVPATLHGFIQMSSNILLIMMMTRIPGGTDVVSAYSVGMVVFGLTTFPAASIATVAASMVGVNLGNSD
QNRAISSGFTCAITGAMVITFTAILTRVFAPELLKFFVKDLSVIKIGDSLLKTLSLVMPVHALGIVFSRGMQGAGDAKTP
FIIAALTGVGARVPLAYIFTFSMGMQSKGIWLAIAVTQVISAVILTYKFKTVVRKRAENIKNY

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=442, Percent_Identity=24.8868778280543, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49541; Mature: 49541

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDLGEQKRRNLILEGNLLKVLWFLSWPVTIQLVVNNVVRVTGTKMVGVLGSDAIAAVG
CCCCCCCHHHCCEEECCCHHHHHHHHCCCHHEEHHHHHHHHCCCCEEEEECCCCHHHHHH
IAQQVLMGVSVPAMGLSMSATAVVANYFGEKNYTGTLYAIGQIILIALLLSGFTTFIGLK
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
YGDNILLLLGAEEQLLQLSHNYLKILFAASFVLITKFPLWGIFQGLGDTRIPMKMDLFSN
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEHHHHHH
ALNVSGNYTFIFGLGPIPSLGLTGAAVGSVLADAVILVRAIGELAKKISGLVLSFYDLFK
HHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLAIMKKIIKIGVPATLHGFIQMSSNILLIMMMTRIPGGTDVVSAYSVGMVVFGLTTFP
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
AASIATVAASMVGVNLGNSDQNRAISSGFTCAITGAMVITFTAILTRVFAPELLKFFVKD
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVIKIGDSLLKTLSLVMPVHALGIVFSRGMQGAGDAKTPFIIAALTGVGARVPLAYIFT
HHHEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHH
FSMGMQSKGIWLAIAVTQVISAVILTYKFKTVVRKRAENIKNY
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRFDLGEQKRRNLILEGNLLKVLWFLSWPVTIQLVVNNVVRVTGTKMVGVLGSDAIAAVG
CCCCCCCHHHCCEEECCCHHHHHHHHCCCHHEEHHHHHHHHCCCCEEEEECCCCHHHHHH
IAQQVLMGVSVPAMGLSMSATAVVANYFGEKNYTGTLYAIGQIILIALLLSGFTTFIGLK
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
YGDNILLLLGAEEQLLQLSHNYLKILFAASFVLITKFPLWGIFQGLGDTRIPMKMDLFSN
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEHHHHHH
ALNVSGNYTFIFGLGPIPSLGLTGAAVGSVLADAVILVRAIGELAKKISGLVLSFYDLFK
HHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLAIMKKIIKIGVPATLHGFIQMSSNILLIMMMTRIPGGTDVVSAYSVGMVVFGLTTFP
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
AASIATVAASMVGVNLGNSDQNRAISSGFTCAITGAMVITFTAILTRVFAPELLKFFVKD
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVIKIGDSLLKTLSLVMPVHALGIVFSRGMQGAGDAKTPFIIAALTGVGARVPLAYIFT
HHHEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHH
FSMGMQSKGIWLAIAVTQVISAVILTYKFKTVVRKRAENIKNY
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]