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The map label for this gene is ywaD [H]

Identifier: 188585781

GI number: 188585781

Start: 1222402

End: 1223790

Strand: Direct

Name: ywaD [H]

Synonym: Nther_1155

Alternate gene names: 188585781

Gene position: 1222402-1223790 (Clockwise)

Preceding gene: 188585780

Following gene: 188585782

Centisome position: 38.62

GC content: 33.77

Gene sequence:

>1389_bases
ATGATGGAAAATATAGTCACAAAAGATTTACAAAAAGTTAGTGTGCTACACTTATTACGTGATCAAAGAGGGGTTTTTGC
CTACTCTTCTAAAATAACTATAACAGACAAGGGGGTTGTAACAATGGAGATTTTTGAAAGTGATGGATTGAGAATGTATG
AAGATATTGTCGATTTAGCAGCTTTAGGGGATCGATTTGCAGGTTCTACAGCAGAAAAAGAAGCTGGTGAAATTGTTAAA
AAATCGTTTATACAATCTGGACTCGAAGTTTATGAAGAATCTTTTGATGTATTTTCTTTTTATGAAAAAAATTCCCAAAT
AAAGTTAAGAAAGCCTCTAGAACTCACATTCGATACCAGGGCAATGTATTATTCACCGGGAACTCATAAAGAAGGATTAC
AAGGTGAACTAGTTTATGTAAAAAATGGTTTAGAACAAGATTATGAAGGTAAAGATGTAGAAGGAAAAATAGTAATTTTC
CATAGAGATGACAAACAAATCAAAGATCATTTCTGGCCAGAAATAAAAACAGCTTCAGAAAAAGGTGCAATTGGTGCAAT
TCTTATTAATTTCGATGATTGGGAATTTATAACTACTCTAGAAACTGGCTATTTTGAACCATCGAAAAGGTTTTTACCTA
TCGAACCAAATGAAATCCCATCTGTTATTGTTAGCAAAAATAAAGGTGACTTGATTCTTGATTTAATGAATCAAGAAAAA
GTTATTGTAGACATTATTGTTGACACGCTAAACGAAAAAATGCGTTCATCCAATATAAGAGGGGTTAAAGCAGGAAGCCA
AAATAATAATGAGAAAATTCTTATATATGGACATAGAGACTCTGCTGGAACGCCTGGAGCGAATGATAATGGATCAGGTA
CCGTAATAATGATGGAACTTGCTCGTCTTTTAAAGGATATGAAATTAAATAGAACTATAGAATTTTTATCAACTGGGGCA
GAAGAACAATTAGGGGCCGCAGGTGCATTGGAGTATATAAATAGGCATAAAAGCGAACTAAATAATATAAAAGCTGCTGT
TGAATTAGATATGGTTGGTAATGGAAATTCATTATGTGTTATGAAGGGAGGAGAGTGGCCAGATAAAACAGTAAATTTCC
CAGACAAAGTTTGTCAGTTTTTTTACGAAAAAGCGCGGGAATATGGATATGCCGTGGAATATGGATTCAATGATTTTGGG
ACACCAGATAGTGGTAAGTTTGCATCAGCAGGTGTTCCTACCACTTGGATATGGGGACCTGATGATATTTATTATCATAG
TCCAGAAGATACTCCTGAAAAGGTTGATCGAAATAAATTGAAAATAGTGGCTGACATGCTGTTAAAAGTAATTTTAGATT
TAGATAAACAAGAAACCCTCAATTTTTAG

Upstream 100 bases:

>100_bases
TAAATTATTTAATCCTTAGTATTCCGAAATATTCGACGACCTCCAATATTGCAAAAATCCCGGGATAAACTTATTGTGAA
AAGCAGTTTTGACAACTGTT

Downstream 100 bases:

>100_bases
GGTGAATAAATCGAGCAAGTAGAAGCTACAGTAATTAGCTTGACTGCTAAGGCTGTAGACAAATAGCCTCCTAATTAGTT
ATTAGAAGGTCATTTCAGCT

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MMENIVTKDLQKVSVLHLLRDQRGVFAYSSKITITDKGVVTMEIFESDGLRMYEDIVDLAALGDRFAGSTAEKEAGEIVK
KSFIQSGLEVYEESFDVFSFYEKNSQIKLRKPLELTFDTRAMYYSPGTHKEGLQGELVYVKNGLEQDYEGKDVEGKIVIF
HRDDKQIKDHFWPEIKTASEKGAIGAILINFDDWEFITTLETGYFEPSKRFLPIEPNEIPSVIVSKNKGDLILDLMNQEK
VIVDIIVDTLNEKMRSSNIRGVKAGSQNNNEKILIYGHRDSAGTPGANDNGSGTVIMMELARLLKDMKLNRTIEFLSTGA
EEQLGAAGALEYINRHKSELNNIKAAVELDMVGNGNSLCVMKGGEWPDKTVNFPDKVCQFFYEKAREYGYAVEYGFNDFG
TPDSGKFASAGVPTTWIWGPDDIYYHSPEDTPEKVDRNKLKIVADMLLKVILDLDKQETLNF

Sequences:

>Translated_462_residues
MMENIVTKDLQKVSVLHLLRDQRGVFAYSSKITITDKGVVTMEIFESDGLRMYEDIVDLAALGDRFAGSTAEKEAGEIVK
KSFIQSGLEVYEESFDVFSFYEKNSQIKLRKPLELTFDTRAMYYSPGTHKEGLQGELVYVKNGLEQDYEGKDVEGKIVIF
HRDDKQIKDHFWPEIKTASEKGAIGAILINFDDWEFITTLETGYFEPSKRFLPIEPNEIPSVIVSKNKGDLILDLMNQEK
VIVDIIVDTLNEKMRSSNIRGVKAGSQNNNEKILIYGHRDSAGTPGANDNGSGTVIMMELARLLKDMKLNRTIEFLSTGA
EEQLGAAGALEYINRHKSELNNIKAAVELDMVGNGNSLCVMKGGEWPDKTVNFPDKVCQFFYEKAREYGYAVEYGFNDFG
TPDSGKFASAGVPTTWIWGPDDIYYHSPEDTPEKVDRNKLKIVADMLLKVILDLDKQETLNF
>Mature_462_residues
MMENIVTKDLQKVSVLHLLRDQRGVFAYSSKITITDKGVVTMEIFESDGLRMYEDIVDLAALGDRFAGSTAEKEAGEIVK
KSFIQSGLEVYEESFDVFSFYEKNSQIKLRKPLELTFDTRAMYYSPGTHKEGLQGELVYVKNGLEQDYEGKDVEGKIVIF
HRDDKQIKDHFWPEIKTASEKGAIGAILINFDDWEFITTLETGYFEPSKRFLPIEPNEIPSVIVSKNKGDLILDLMNQEK
VIVDIIVDTLNEKMRSSNIRGVKAGSQNNNEKILIYGHRDSAGTPGANDNGSGTVIMMELARLLKDMKLNRTIEFLSTGA
EEQLGAAGALEYINRHKSELNNIKAAVELDMVGNGNSLCVMKGGEWPDKTVNFPDKVCQFFYEKAREYGYAVEYGFNDFG
TPDSGKFASAGVPTTWIWGPDDIYYHSPEDTPEKVDRNKLKIVADMLLKVILDLDKQETLNF

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 52084; Mature: 52084

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMENIVTKDLQKVSVLHLLRDQRGVFAYSSKITITDKGVVTMEIFESDGLRMYEDIVDLA
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECEEEEECCCEEEEEEECCCCCHHHHHHHHHH
ALGDRFAGSTAEKEAGEIVKKSFIQSGLEVYEESFDVFSFYEKNSQIKLRKPLELTFDTR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCEEEEECE
AMYYSPGTHKEGLQGELVYVKNGLEQDYEGKDVEGKIVIFHRDDKQIKDHFWPEIKTASE
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCC
KGAIGAILINFDDWEFITTLETGYFEPSKRFLPIEPNEIPSVIVSKNKGDLILDLMNQEK
CCCEEEEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCE
VIVDIIVDTLNEKMRSSNIRGVKAGSQNNNEKILIYGHRDSAGTPGANDNGSGTVIMMEL
EEEHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEHHHH
ARLLKDMKLNRTIEFLSTGAEEQLGAAGALEYINRHKSELNNIKAAVELDMVGNGNSLCV
HHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCEEEE
MKGGEWPDKTVNFPDKVCQFFYEKAREYGYAVEYGFNDFGTPDSGKFASAGVPTTWIWGP
EECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCEEEEECC
DDIYYHSPEDTPEKVDRNKLKIVADMLLKVILDLDKQETLNF
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MMENIVTKDLQKVSVLHLLRDQRGVFAYSSKITITDKGVVTMEIFESDGLRMYEDIVDLA
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECEEEEECCCEEEEEEECCCCCHHHHHHHHHH
ALGDRFAGSTAEKEAGEIVKKSFIQSGLEVYEESFDVFSFYEKNSQIKLRKPLELTFDTR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCEEEEECE
AMYYSPGTHKEGLQGELVYVKNGLEQDYEGKDVEGKIVIFHRDDKQIKDHFWPEIKTASE
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCC
KGAIGAILINFDDWEFITTLETGYFEPSKRFLPIEPNEIPSVIVSKNKGDLILDLMNQEK
CCCEEEEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCE
VIVDIIVDTLNEKMRSSNIRGVKAGSQNNNEKILIYGHRDSAGTPGANDNGSGTVIMMEL
EEEHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEHHHH
ARLLKDMKLNRTIEFLSTGAEEQLGAAGALEYINRHKSELNNIKAAVELDMVGNGNSLCV
HHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCEEEE
MKGGEWPDKTVNFPDKVCQFFYEKAREYGYAVEYGFNDFGTPDSGKFASAGVPTTWIWGP
EECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCEEEEECC
DDIYYHSPEDTPEKVDRNKLKIVADMLLKVILDLDKQETLNF
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]