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The map label for this gene is aroB [H]

Identifier: 188584719

GI number: 188584719

Start: 91352

End: 92251

Strand: Direct

Name: aroB [H]

Synonym: Nther_0077

Alternate gene names: 188584719

Gene position: 91352-92251 (Clockwise)

Preceding gene: 188584718

Following gene: 188584720

Centisome position: 2.89

GC content: 35.67

Gene sequence:

>900_bases
ATGACAAACCAGATTAAAGCTGCGATTGATATAGGAAGCAATTCAATTAGGCTGCTAATAGCTAGAGTCAATAAAAATGG
ACTAGAGGAGCTATATAGGGATGTCCAAACTACTCGGTTAGGGGAAGGAATTCAACACTATGAAAAATTAACCCAAAGAT
CAATCAACGATTCTGTCCATGTACTTAAGGAATATTATCAGATAATCCATCAGTATCAAGTAAACGAAACTAAAATTGTT
GCCACCAGTGCAATAAGGGAAGCATCAAATAATCAAGAGTTTTTTAATGAAGTTAACAGAGCCATAGCTCAACCAATCAA
TATCGAAGTAGTAGATGGAATTAGGGAAGCAGCCCTTAATTACAAAGGTGCTACTATGGAATTAACAGAAGATGCCTTTG
TTTTTGATCTAGGTGGTGGGAGTCTTGAAATAATACCTCAAGATCCAAATTCTATGGCTAGCTTTCCCATAGGTGCTGTT
AAAGCAACTGAAAGTTACTGTGATGAAGAAGGGCGTATTAGAAATCACGAAGACTTAAGGAAAGCAGTCCAAAAAATAAT
CACTACAGAAATATTAAGTGCATATCAAGAAAATATACAGGTAGTTGGTGTTGGCGGAACGGCCACTTATTTGGCAAAGG
CTTATAAAAAACTCCCAGTTTATAAAAAAGAGGATATTCATGGAACATATCTGAGTAGGACTGACCTAAATAATTTATTG
AAGGGTATGGAAAAGTATGATTTGGAACAACGTGTTGATGAATTTTTTCTCACACCTAACAGGGCAGATATAATAATTGC
AGGAGGTTATATAATAAATTATTTACTTCAAGAGATTGGCGCGAAAGGATATTGGGCTAGTGACAATGATATGTTAATGG
GGCTGATTTTGGAGATTTAA

Upstream 100 bases:

>100_bases
GGTGCTTGTTTTCGTATTGAACTCCCTTTATATGATGTTGATGGAGTTAACAGTATATGTAGAAATGTTTATATACCATA
TTGTGAAAGGGTGGCTGATT

Downstream 100 bases:

>100_bases
ACTTTTTGATTCGAGATCAATACTGAGAATTTGACAAATATGTTTACTTAAGTTATAATTATAATCACTGTCGACGCGGG
GTGGAGCAGTCTGGTAGCTC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTNQIKAAIDIGSNSIRLLIARVNKNGLEELYRDVQTTRLGEGIQHYEKLTQRSINDSVHVLKEYYQIIHQYQVNETKIV
ATSAIREASNNQEFFNEVNRAIAQPINIEVVDGIREAALNYKGATMELTEDAFVFDLGGGSLEIIPQDPNSMASFPIGAV
KATESYCDEEGRIRNHEDLRKAVQKIITTEILSAYQENIQVVGVGGTATYLAKAYKKLPVYKKEDIHGTYLSRTDLNNLL
KGMEKYDLEQRVDEFFLTPNRADIIIAGGYIINYLLQEIGAKGYWASDNDMLMGLILEI

Sequences:

>Translated_299_residues
MTNQIKAAIDIGSNSIRLLIARVNKNGLEELYRDVQTTRLGEGIQHYEKLTQRSINDSVHVLKEYYQIIHQYQVNETKIV
ATSAIREASNNQEFFNEVNRAIAQPINIEVVDGIREAALNYKGATMELTEDAFVFDLGGGSLEIIPQDPNSMASFPIGAV
KATESYCDEEGRIRNHEDLRKAVQKIITTEILSAYQENIQVVGVGGTATYLAKAYKKLPVYKKEDIHGTYLSRTDLNNLL
KGMEKYDLEQRVDEFFLTPNRADIIIAGGYIINYLLQEIGAKGYWASDNDMLMGLILEI
>Mature_298_residues
TNQIKAAIDIGSNSIRLLIARVNKNGLEELYRDVQTTRLGEGIQHYEKLTQRSINDSVHVLKEYYQIIHQYQVNETKIVA
TSAIREASNNQEFFNEVNRAIAQPINIEVVDGIREAALNYKGATMELTEDAFVFDLGGGSLEIIPQDPNSMASFPIGAVK
ATESYCDEEGRIRNHEDLRKAVQKIITTEILSAYQENIQVVGVGGTATYLAKAYKKLPVYKKEDIHGTYLSRTDLNNLLK
GMEKYDLEQRVDEFFLTPNRADIIIAGGYIINYLLQEIGAKGYWASDNDMLMGLILEI

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=170, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788848, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33675; Mature: 33543

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQIKAAIDIGSNSIRLLIARVNKNGLEELYRDVQTTRLGEGIQHYEKLTQRSINDSVH
CCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VLKEYYQIIHQYQVNETKIVATSAIREASNNQEFFNEVNRAIAQPINIEVVDGIREAALN
HHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHC
YKGATMELTEDAFVFDLGGGSLEIIPQDPNSMASFPIGAVKATESYCDEEGRIRNHEDLR
CCCCEEEECCCEEEEEECCCEEEEEECCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
KAVQKIITTEILSAYQENIQVVGVGGTATYLAKAYKKLPVYKKEDIHGTYLSRTDLNNLL
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
KGMEKYDLEQRVDEFFLTPNRADIIIAGGYIINYLLQEIGAKGYWASDNDMLMGLILEI
HHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHEECC
>Mature Secondary Structure 
TNQIKAAIDIGSNSIRLLIARVNKNGLEELYRDVQTTRLGEGIQHYEKLTQRSINDSVH
CCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VLKEYYQIIHQYQVNETKIVATSAIREASNNQEFFNEVNRAIAQPINIEVVDGIREAALN
HHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHC
YKGATMELTEDAFVFDLGGGSLEIIPQDPNSMASFPIGAVKATESYCDEEGRIRNHEDLR
CCCCEEEECCCEEEEEECCCEEEEEECCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
KAVQKIITTEILSAYQENIQVVGVGGTATYLAKAYKKLPVYKKEDIHGTYLSRTDLNNLL
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
KGMEKYDLEQRVDEFFLTPNRADIIIAGGYIINYLLQEIGAKGYWASDNDMLMGLILEI
HHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]