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The map label for this gene is yabD [H]

Identifier: 188584686

GI number: 188584686

Start: 59054

End: 59824

Strand: Direct

Name: yabD [H]

Synonym: Nther_0044

Alternate gene names: 188584686

Gene position: 59054-59824 (Clockwise)

Preceding gene: 188584685

Following gene: 188584687

Centisome position: 1.87

GC content: 35.67

Gene sequence:

>771_bases
TTGAATATTATTGATACACATGCTCATCTAGATGATAAACGCTTTTCTTCTGATTTGGAAGATGTGATTGAAAGGGCTAA
ACAAAAGAAAGTCTCTCAGATTATTAATGTAGGTATTAATATCGACTCATCGCAAAAGTCTGTGGAAATGGCTAAAAAGT
ATCCAGAAATATATGCAACAGTAGGAGTCCATCCCCATGATGCAAAAAAAGTTCCGGATAACTATTTAGACGAATTAAAG
AAAATGGTTACTGAGAATAAAGATGTGGTTGTTGGGATTGGAGAAATGGGGTTAGACTATTTTAAGAACCGTTCACCCCA
AGAAACGCAAAAAAGTATTTTTAGAGCCCAATTAGAATTTGCCAAAGAATTACAGCTCCCTGTTATAATACATGACCGGG
CTGCCCATGAGGATGCCCTTGAAATAGTAAAAGATTTTCAAAATGATGTTTTTGGAGTTTTTCATTGTTTTGCGGGAGAT
GAAGAAATAGCTTCTCAAGTTATGGATATGGGTTTTTACATTTCCTTTACAGGTAATATATCTTTTCAAAAAGCTGACAA
GTTAAGGGATGTTGTTAAATACGCTCCATTGTCTAGAATCATGATTGAGACTGATTGCCCTTATATGGCTCCTGTTCCCT
TTAGAGGAAAAAGAAATGAACCAGCCTTTACCAGACTTGTTGCAGAAGAAGTCGCTGACATAAAAGGAGAAAGCTTCGAA
GATGTAGTAACAACTACAACAAAAAATGCCAAAGATTTATTCCGGATTTAG

Upstream 100 bases:

>100_bases
CAGGGAATGATCCTAGCTGCCAATGATGAAGGTACAAATCAGTTGGAATTACCCAATTTTATCTCAGACAAAATCACTAA
AGGAAGTCAGGTGAGGTAAA

Downstream 100 bases:

>100_bases
GGGGGACTAAAATGAAAACTATGAGAATAAGTCTCTTGTTTGGATTGTTTCTCTTATTTTTGCAAATGGATAGTGGAGCT
CTAGTTATGGAACAGGAATA

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNIIDTHAHLDDKRFSSDLEDVIERAKQKKVSQIINVGINIDSSQKSVEMAKKYPEIYATVGVHPHDAKKVPDNYLDELK
KMVTENKDVVVGIGEMGLDYFKNRSPQETQKSIFRAQLEFAKELQLPVIIHDRAAHEDALEIVKDFQNDVFGVFHCFAGD
EEIASQVMDMGFYISFTGNISFQKADKLRDVVKYAPLSRIMIETDCPYMAPVPFRGKRNEPAFTRLVAEEVADIKGESFE
DVVTTTTKNAKDLFRI

Sequences:

>Translated_256_residues
MNIIDTHAHLDDKRFSSDLEDVIERAKQKKVSQIINVGINIDSSQKSVEMAKKYPEIYATVGVHPHDAKKVPDNYLDELK
KMVTENKDVVVGIGEMGLDYFKNRSPQETQKSIFRAQLEFAKELQLPVIIHDRAAHEDALEIVKDFQNDVFGVFHCFAGD
EEIASQVMDMGFYISFTGNISFQKADKLRDVVKYAPLSRIMIETDCPYMAPVPFRGKRNEPAFTRLVAEEVADIKGESFE
DVVTTTTKNAKDLFRI
>Mature_256_residues
MNIIDTHAHLDDKRFSSDLEDVIERAKQKKVSQIINVGINIDSSQKSVEMAKKYPEIYATVGVHPHDAKKVPDNYLDELK
KMVTENKDVVVGIGEMGLDYFKNRSPQETQKSIFRAQLEFAKELQLPVIIHDRAAHEDALEIVKDFQNDVFGVFHCFAGD
EEIASQVMDMGFYISFTGNISFQKADKLRDVVKYAPLSRIMIETDCPYMAPVPFRGKRNEPAFTRLVAEEVADIKGESFE
DVVTTTTKNAKDLFRI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=204, Percent_Identity=35.2941176470588, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=31.6981132075472, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=30.9433962264151, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=31.5018315018315, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI225903439, Length=180, Percent_Identity=35.5555555555556, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=29.3436293436293, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI225903424, Length=207, Percent_Identity=29.4685990338164, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=29.5652173913043, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=36.9230769230769, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=31.9230769230769, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=31.6205533596838, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=35.9154929577465, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=29.9242424242424, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17565396, Length=216, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=219, Percent_Identity=28.310502283105, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=33.2155477031802, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI221330018, Length=298, Percent_Identity=31.8791946308725, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24586117, Length=276, Percent_Identity=31.8840579710145, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29109; Mature: 29109

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIDTHAHLDDKRFSSDLEDVIERAKQKKVSQIINVGINIDSSQKSVEMAKKYPEIYAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEE
VGVHPHDAKKVPDNYLDELKKMVTENKDVVVGIGEMGLDYFKNRSPQETQKSIFRAQLEF
CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKELQLPVIIHDRAAHEDALEIVKDFQNDVFGVFHCFAGDEEIASQVMDMGFYISFTGNI
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCC
SFQKADKLRDVVKYAPLSRIMIETDCPYMAPVPFRGKRNEPAFTRLVAEEVADIKGESFE
CHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
DVVTTTTKNAKDLFRI
HHHHHCCCCHHHHHCC
>Mature Secondary Structure
MNIIDTHAHLDDKRFSSDLEDVIERAKQKKVSQIINVGINIDSSQKSVEMAKKYPEIYAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEE
VGVHPHDAKKVPDNYLDELKKMVTENKDVVVGIGEMGLDYFKNRSPQETQKSIFRAQLEF
CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKELQLPVIIHDRAAHEDALEIVKDFQNDVFGVFHCFAGDEEIASQVMDMGFYISFTGNI
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCC
SFQKADKLRDVVKYAPLSRIMIETDCPYMAPVPFRGKRNEPAFTRLVAEEVADIKGESFE
CHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
DVVTTTTKNAKDLFRI
HHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]