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The map label for this gene is hcpD [H]

Identifier: 188527523

GI number: 188527523

Start: 715567

End: 716625

Strand: Reverse

Name: hcpD [H]

Synonym: HPSH_03725

Alternate gene names: 188527523

Gene position: 716625-715567 (Counterclockwise)

Preceding gene: 188527524

Following gene: 188527522

Centisome position: 44.55

GC content: 44.38

Gene sequence:

>1059_bases
ATGCTCAAAAAAAGTTTGTTATTGCTTGTTTTTTTAGTCTTACAGCTTAGCGGTGCTGAAGAAAACAATCAAGCCCAAAA
AAACACACCCCCTGAATTAAACCCCGCTAACGCTAAGGGCGCACCAAACCCTAACACCCAAATCACCCCTAAAAACGATA
ATTCTAATTTGTTAGACAAATTGGGTTCGCCTGAAAACGCTCAAACCGAGCTTTCTGCCGGTATTGAATTGGCTAAAAAG
GGCGATTATCAAGGGGCTTTTAAGCTTTTTTCCCAATCGTGCGATAACGGCAATGCGGCCGGGTGTTTTGCAGTGGGGGC
GATGTATGCTAATGGGGTAGGCATCCAAACGAACAGACTAAAAGCCGCTCGCTATTATGAAATGGGTTGCAGTGGGGGCG
ATGCGACCGCTTGCGCGAATCTGGCTCAAATGTATGAAAACAAGAAAAATGCGGATACGAACGACAAAGAAAACGCTTTG
CAGTTGTATGCGGTGGCTTGTCAAGGGGGGGATATGATCGCATGCAATAATTTGGGGTGGATGTTTGCTAACGGGAGTGG
GGTCCCAAAAGATTATTACAAAGCGATGGGTTATTATAAATTTTCATGCGATAATGGGAATGATATGGGGTGTTATAATC
TGGGCTTGATGTCTAATGTGAATAATATTTATGGCATTGATAAGGCGCAACTCAGTCAAGTGGATTTGAATTATTTGGCG
TGTAACGCTGGGGATATGATGGGGTGCGCGAATTTAGGCTGGATTTATGCGAATGGGGATTTAGGGGCTCCTTTGAATAA
CCACTATGCGGCGAAATATTTTCAAATGGCATGCGATGGGGGGATTTTGGGGAGCTGTAACAATTTAGGCGTGCTGTATC
AAAAGGGCTTAGGCGTGCCTCAAGACGATCAGAGGGCTTTGGATTTATTCTCGTATGCGTGCGATAATGGTTTTGAGTCA
AGCTGTCGCAATTACGGGAATTTCAAAGAGCATTTATTGCGCGTGAATCCTAATTACGGGCGCTTGTTCATGCCGTATCA
TTCTTATGAGATACCCTAG

Upstream 100 bases:

>100_bases
GCGTGCATTTTCGTTCCAATAGCCAAAATGGTAAGCTGATTGCTTTTAGGAGCGTGAAAAAAATTGAGTTGAATCAAAAC
CTGCATTAAGGATTAAAAGA

Downstream 100 bases:

>100_bases
TAATAGCCGTTTTTTAATAAATTCAGCCACAAATTGCGGTTTTTTCAAAAGTTTAAGCTTCTTTTTTTTTTTTTTTTGTA
TTTAATACTCGGTATGATTT

Product: cysteine-rich protein F

Products: NA

Alternate protein names: Cysteine-rich protein D; Penicillin-binding protein 4; PBP 4 [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLKKSLLLLVFLVLQLSGAEENNQAQKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADTNDKENAL
QLYAVACQGGDMIACNNLGWMFANGSGVPKDYYKAMGYYKFSCDNGNDMGCYNLGLMSNVNNIYGIDKAQLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYHSYEIP

Sequences:

>Translated_352_residues
MLKKSLLLLVFLVLQLSGAEENNQAQKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADTNDKENAL
QLYAVACQGGDMIACNNLGWMFANGSGVPKDYYKAMGYYKFSCDNGNDMGCYNLGLMSNVNNIYGIDKAQLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYHSYEIP
>Mature_352_residues
MLKKSLLLLVFLVLQLSGAEENNQAQKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADTNDKENAL
QLYAVACQGGDMIACNNLGWMFANGSGVPKDYYKAMGYYKFSCDNGNDMGCYNLGLMSNVNNIYGIDKAQLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYHSYEIP

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. Binds to penicillin [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI19923669, Length=291, Percent_Identity=26.4604810996564, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI151301150, Length=252, Percent_Identity=26.984126984127, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081769, Length=234, Percent_Identity=24.7863247863248, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17563256, Length=262, Percent_Identity=25.1908396946565, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355295, Length=273, Percent_Identity=25.6410256410256, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 38098; Mature: 38098

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKSLLLLVFLVLQLSGAEENNQAQKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
LGSPENAQTELSAGIELAKKGDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRL
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCE
KAARYYEMGCSGGDATACANLAQMYENKKNADTNDKENALQLYAVACQGGDMIACNNLGW
EHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCE
MFANGSGVPKDYYKAMGYYKFSCDNGNDMGCYNLGLMSNVNNIYGIDKAQLSQVDLNYLA
EEECCCCCCHHHHHHCCEEEEECCCCCCCCEEECHHHHCCCHHCCCCHHHHHHCCCEEEE
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVP
ECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCC
QDDQRALDLFSYACDNGFESSCRNYGNFKEHLLRVNPNYGRLFMPYHSYEIP
CCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHEEEECCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLKKSLLLLVFLVLQLSGAEENNQAQKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
LGSPENAQTELSAGIELAKKGDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRL
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCE
KAARYYEMGCSGGDATACANLAQMYENKKNADTNDKENALQLYAVACQGGDMIACNNLGW
EHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCE
MFANGSGVPKDYYKAMGYYKFSCDNGNDMGCYNLGLMSNVNNIYGIDKAQLSQVDLNYLA
EEECCCCCCHHHHHHCCEEEEECCCCCCCCEEECHHHHCCCHHCCCCHHHHHHCCCEEEE
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVP
ECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCC
QDDQRALDLFSYACDNGFESSCRNYGNFKEHLLRVNPNYGRLFMPYHSYEIP
CCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHEEEECCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185; 10438788 [H]