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The map label for this gene is modB [H]

Identifier: 188527260

GI number: 188527260

Start: 448401

End: 449075

Strand: Direct

Name: modB [H]

Synonym: HPSH_02335

Alternate gene names: 188527260

Gene position: 448401-449075 (Clockwise)

Preceding gene: 188527259

Following gene: 188527261

Centisome position: 27.88

GC content: 36.89

Gene sequence:

>675_bases
ATGGATCATGAGTTTTTGATTACCATGCGTTTGAGCTTTTCTTTAGCCTTTATTACCACCCTTATTTTACTCCCTATAGG
GATTTTTTTAGGCTATTTTTTAAGCCTTAAACGCAATCTTTTAACGAGCTTGACAGAAACGCTTGTGTACATGCCTTTAG
TTTTACCCCCAAGCGTGCTAGGGTTTTATCTTCTTTTAATTTTTTCGCCTTCTTCTTTTTTGGGAGCGTTTTTACAAGAT
GCGTTAAATGTGAAACTTGTTTTTAGTTTTCAAGGGCTTATTTTAGGGAGTGTGATTTTTTCTTTACCCTTTATGGTAAG
CCCTATTAAAAGCGCGTTAATTTCCTTGCCCACTTCTTTAAAAGAAGCCAGTTATAGTTTGGGTAAAGGGGAATATTACA
CCCTTTTTTTTGTCCTACTCCCTAACATCAAACCCAGTTTATTGATGGCTATCATTACAACTTTTACGCACACTATAGGT
GAATTTGGCGTGGTAATGATGCTTGGGGGTGATATATTAGGGGAAACAAGAGTGGCCAGTATTGCGGTTTTTAACGAAAC
TGAAGCGCTCAATTACCCTAAAGCCCACCAATACGCCTTAACGCTCACGCTTATCAGTTTTAGTCTCTTATTTGTTACCC
TATTTTTGAATAAAAAACAAAGCTCGTTTTTATGA

Upstream 100 bases:

>100_bases
AGCCAAAGTCTTTAAAGATTTTTTATTCAGCCCTAAAGCCAGAGCTATTTTTAAAGAATACGGCTATATTGTGGATTAAA
GCGCATAAAAAAGGCGAACA

Downstream 100 bases:

>100_bases
TAAAAGCGCGATTTAAAAAACACCTTTTAGGATCTAGGGGCGCGTTTGATTTGAATATAGACTTAGAAATTAAAGAAGCA
GAAGTTGTGGCTTTATTAGG

Product: molybdenum ABC transporter ModB

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDHEFLITMRLSFSLAFITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
ALNVKLVFSFQGLILGSVIFSLPFMVSPIKSALISLPTSLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAVFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL

Sequences:

>Translated_224_residues
MDHEFLITMRLSFSLAFITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
ALNVKLVFSFQGLILGSVIFSLPFMVSPIKSALISLPTSLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAVFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
>Mature_224_residues
MDHEFLITMRLSFSLAFITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
ALNVKLVFSFQGLILGSVIFSLPFMVSPIKSALISLPTSLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAVFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=208, Percent_Identity=27.8846153846154, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786980, Length=217, Percent_Identity=29.4930875576037, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI87082099, Length=179, Percent_Identity=31.2849162011173, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24820; Mature: 24820

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHEFLITMRLSFSLAFITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GFYLLLIFSPSSFLGAFLQDALNVKLVFSFQGLILGSVIFSLPFMVSPIKSALISLPTSL
HHHHHHHHCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
KEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIGEFGVVMMLGGDILGETRVAS
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHE
IAVFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
EEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MDHEFLITMRLSFSLAFITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GFYLLLIFSPSSFLGAFLQDALNVKLVFSFQGLILGSVIFSLPFMVSPIKSALISLPTSL
HHHHHHHHCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
KEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIGEFGVVMMLGGDILGETRVAS
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHE
IAVFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
EEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491722 [H]