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The map label for this gene is minD [H]

Identifier: 188527137

GI number: 188527137

Start: 329469

End: 330275

Strand: Direct

Name: minD [H]

Synonym: HPSH_01720

Alternate gene names: 188527137

Gene position: 329469-330275 (Clockwise)

Preceding gene: 188527136

Following gene: 188527138

Centisome position: 20.48

GC content: 42.13

Gene sequence:

>807_bases
ATGGCAATAGTAGTTACTATCACTTCAGGTAAGGGGGGCGTGGGTAAAAGCACCACCGCGGCTAATTTAGCGATCGGCTT
GGCTGAGAGCGGTAAAAAAGTCGTAGCGGTTGATTTTGACATAGGCCTTAGGAACTTGGATATGATTTTAGGCTTAGAAA
ATCGCATTGTTTATGATGTGGTGGATGTGATGGAAAAAAATTGCAACCTTTCGCAGGCTTTAATCACGGATAAAAAGACC
AAAAACCTTTCTTTTTTAGCGGCTTCACAAAGCAAGGATAAAAATGTTTTAGATAAGGAAAAAGTAGCGATTTTAATCAA
CGCTTTAAGGACGGATTTTGACTATATTTTGATTGATTCACCGGCTGGGATTGAAAGCGGTTTTGAGCATGCGATTTTGC
ATGCGGACATGGCGTTAGTGGTGGTAACGCCGGAGGTGAGCTCTTTAAGGGATAGCGACAGAGTGATTGGCATTATTGAT
GCGAAGTCTAATCGGGCTAAAAAGGGCATGGAAGTGCATAAGCATTTGATAATCAATCGCTTAAAACCCGAATTAGTGGC
AAATGGCGAGATGATTTCCATAGAAGAAGTGCTTAAGATTTTATGCCTGCCTTTAATTGGGATCATTCCTGAAGACAGCC
ATATTATTTCAGCGACCAATAAGGGCGAGCCAGTGATTCGCACGGATTGCGAGAGCGCGAAGGCTTACCAGCGCATCACC
AGAAGGATTTTAGGCGAAGAAGTGGAATATGTGGAATTTAAGGCTAAAAAAGGCTTTTTTAGCGCGTTAAAAGGGATATT
TTCATGA

Upstream 100 bases:

>100_bases
CACAGAGAGGAAAGCCCTTAAAGAGACTAAAATAGAACAAATTGGGGAAATTTTACGCGCCCCATTCAATCATAAAAAAT
AAATCATTAAAAGGAATTAT

Downstream 100 bases:

>100_bases
GTTTGTTTGATTTTTTTAAAAACAAGGGGAGCGCGGCTACCGCAACAGACAGATTAAAATTGATTTTAGCCAAAGAGCGC
ACTTTAAATTTACCCTACAT

Product: cell division inhibitor (minD)

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKT
KNLSFLAASQSKDKNVLDKEKVAILINALRTDFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIID
AKSNRAKKGMEVHKHLIINRLKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRIT
RRILGEEVEYVEFKAKKGFFSALKGIFS

Sequences:

>Translated_268_residues
MAIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKT
KNLSFLAASQSKDKNVLDKEKVAILINALRTDFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIID
AKSNRAKKGMEVHKHLIINRLKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRIT
RRILGEEVEYVEFKAKKGFFSALKGIFS
>Mature_267_residues
AIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKTK
NLSFLAASQSKDKNVLDKEKVAILINALRTDFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDA
KSNRAKKGMEVHKHLIINRLKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRITR
RILGEEVEYVEFKAKKGFFSALKGIFS

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=50, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29216; Mature: 29085

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDV
CEEEEEEECCCCCCCCCCCHHHEEEEECCCCCEEEEEEECCCCCCCCEEEECCCHHHHHH
VDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNVLDKEKVAILINALRTDFDYILIDS
HHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
PAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDAKSNRAKKGMEVHKHLIINR
CCCCCCCHHHHHEECCEEEEEECCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRIT
CCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCHHHHHHHHHH
RRILGEEVEYVEFKAKKGFFSALKGIFS
HHHHCCCHHEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
AIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDV
EEEEEEECCCCCCCCCCCHHHEEEEECCCCCEEEEEEECCCCCCCCEEEECCCHHHHHH
VDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNVLDKEKVAILINALRTDFDYILIDS
HHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
PAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDAKSNRAKKGMEVHKHLIINR
CCCCCCCHHHHHEECCEEEEEECCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRIT
CCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCHHHHHHHHHH
RRILGEEVEYVEFKAKKGFFSALKGIFS
HHHHCCCHHEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]