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The map label for this gene is mtnU [H]

Identifier: 188527115

GI number: 188527115

Start: 310646

End: 311530

Strand: Direct

Name: mtnU [H]

Synonym: HPSH_01600

Alternate gene names: 188527115

Gene position: 310646-311530 (Clockwise)

Preceding gene: 188527114

Following gene: 188527118

Centisome position: 19.31

GC content: 42.26

Gene sequence:

>885_bases
TTGAAAACAAAAAATCCCGCTAAAAGAATCCTAAAAACGGCTGTGATTCAAATGCAATCCAAACCCTACGCCTTAAATGA
AAACCTGCAATTAGCGCTCAATCTCGCCAAAGAAGCCCACAACAAAGGTGCGAATCTCATTGTTTTACCGGAATTGTTTG
ATAGCGGTTATTGCGTGAATGATAAGGATGCGGATTTTGGGATAGATCTTAAAGCGATAGAGCATGGAAAGGAAACGCTA
AAAAACGAGTCGTTGAGAGCGTTAAGCGATTTTGCAAAATCTAATAAGGTGCATCTAGTGGCGTGCAGCATTGAAAAAAC
GGATAAAAAACTCTACGACAGCGCTTATATCATTCCACCAAAAGGCGGGATCGTTGGAAAACACCGCAAGGTTTATTTGT
GGGGCGATGAAAAATCGCGTTTCAAAAGGGGTAAAAAATACGAGGTTTTTACGCTGGATTTTGGGGATTTTAGCGCGAAA
GTGGGTTTGCAAGTTTGCTATGAAATCGGCTTTGGCGTGGGAGCGAATCTTTTAGCGTTACAAGGGGCGGAGGTTTTAAT
CTATCCTAGCGCGTTTGGCAAAGCTAGGGCTTATAACTGGGATTTATTGAGCAAGACTAGAGCGTTAGAAAATGGCTGTT
TTGTGTGTGCGTGCAATCATAGTGGGGAAGAAACTAACGCTCAATTAAAACAAACGCTAGAGTTTGCCGGCGATTCAAGA
ATCATCGCGCCCAACGGGAAAATCATCGTGCAAGCCACCAAGCTTAATGAAGCCATTATCGCTGAAATGGATTTAAACGA
AGCGGCGCTACAACGCCAAAAAATTCCTTATTTACAAGATTTTGACACCAAACTCACCAAAAAGGGGTTTGGAAAACTCA
CTTAA

Upstream 100 bases:

>100_bases
ATAATGGTAAGTTTTGACACAAACTCGTATGGATTTTAACCCCATTAATCCTCTTTTAATTTCTAATCCTATACAATAAA
AACAAAAATGGGAGTGGATC

Downstream 100 bases:

>100_bases
AAAGGAGCGATTATGGCAAAAGAAATTTTAGTGGCTTATGGCGTGGATATTGATGCGGTGGCTGGTTGGCTAGGGAGCTA
TGGCGGGGAGGATTCGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVNDKDADFGIDLKAIEHGKETL
KNESLRALSDFAKSNKVHLVACSIEKTDKKLYDSAYIIPPKGGIVGKHRKVYLWGDEKSRFKRGKKYEVFTLDFGDFSAK
VGLQVCYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKTRALENGCFVCACNHSGEETNAQLKQTLEFAGDSR
IIAPNGKIIVQATKLNEAIIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT

Sequences:

>Translated_294_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVNDKDADFGIDLKAIEHGKETL
KNESLRALSDFAKSNKVHLVACSIEKTDKKLYDSAYIIPPKGGIVGKHRKVYLWGDEKSRFKRGKKYEVFTLDFGDFSAK
VGLQVCYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKTRALENGCFVCACNHSGEETNAQLKQTLEFAGDSR
IIAPNGKIIVQATKLNEAIIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
>Mature_294_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVNDKDADFGIDLKAIEHGKETL
KNESLRALSDFAKSNKVHLVACSIEKTDKKLYDSAYIIPPKGGIVGKHRKVYLWGDEKSRFKRGKKYEVFTLDFGDFSAK
VGLQVCYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKTRALENGCFVCACNHSGEETNAQLKQTLEFAGDSR
IIAPNGKIIVQATKLNEAIIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=281, Percent_Identity=28.4697508896797, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI297632348, Length=282, Percent_Identity=26.5957446808511, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI5031947, Length=282, Percent_Identity=26.5957446808511, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI297632350, Length=282, Percent_Identity=26.5957446808511, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1786412, Length=244, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17533173, Length=295, Percent_Identity=24.406779661017, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557111, Length=287, Percent_Identity=25.0871080139373, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323383, Length=281, Percent_Identity=29.1814946619217, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355835, Length=282, Percent_Identity=28.0141843971631, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17933642, Length=261, Percent_Identity=27.9693486590038, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 32581; Mature: 32581

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVN
CCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHCCCCCEEEEHHHCCCCCEEC
DKDADFGIDLKAIEHGKETLKNESLRALSDFAKSNKVHLVACSIEKTDKKLYDSAYIIPP
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCEEEECC
KGGIVGKHRKVYLWGDEKSRFKRGKKYEVFTLDFGDFSAKVGLQVCYEIGFGVGANLLAL
CCCCCCCCEEEEEECCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEE
QGAEVLIYPSAFGKARAYNWDLLSKTRALENGCFVCACNHSGEETNAQLKQTLEFAGDSR
CCCEEEEEECCCCCCEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
IIAPNGKIIVQATKLNEAIIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
EECCCCEEEEEEECCCCEEEEECCCCHHHHHHHCCCCHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVN
CCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHCCCCCEEEEHHHCCCCCEEC
DKDADFGIDLKAIEHGKETLKNESLRALSDFAKSNKVHLVACSIEKTDKKLYDSAYIIPP
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCEEEECC
KGGIVGKHRKVYLWGDEKSRFKRGKKYEVFTLDFGDFSAKVGLQVCYEIGFGVGANLLAL
CCCCCCCCEEEEEECCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEE
QGAEVLIYPSAFGKARAYNWDLLSKTRALENGCFVCACNHSGEETNAQLKQTLEFAGDSR
CCCEEEEEECCCCCCEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
IIAPNGKIIVQATKLNEAIIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
EECCCCEEEEEEECCCCEEEEECCCCHHHHHHHCCCCHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]