Click here to switch to the map view.

The map label for this gene is 188527090

Identifier: 188527090

GI number: 188527090

Start: 277379

End: 278944

Strand: Direct

Name: 188527090

Synonym: HPSH_01475

Alternate gene names: NA

Gene position: 277379-278944 (Clockwise)

Preceding gene: 188527089

Following gene: 188527091

Centisome position: 17.24

GC content: 37.04

Gene sequence:

>1566_bases
ATGGCATTAAGGGTATTATTATTCTTTTGTTTTTTGTTTTTACAAGCAGAAGATAAAAGCCAAGAACTATTGACCATACA
AAAACAAATGGCTTTGGTGGATAAAAAACTCGCCAAAGACGATAATGTGTGGTTGAAAAAATTTGAAAACTATAAGATCT
ACAATCAAATTTATACCGAAAAAGAGAGCGTGAGGCAGGAATTAAGGCGTTTAAAAAATAAAAAAAGCAAGGATTTATTA
AAGATTAGCACCTTAGAGCACACCTTAAAGGCTTTAGAATCCCAGCAAAAAATGTTTGAAAGCTATGGGGTCAATCCTTT
TAAGGACTTGATAGAGCGCCCTAATATCCCCAATATCCCTAATATCGCTAACCCTATTGCGATCATTGATGGCATTTCTT
TCATTAAAAGCATGCGTTTAAAGCATGAAAGTCTTAAAAATAACCAGACTGCTTTAGAAGAAGTTTTAAGGCTTTTAGAT
CAAAAACACCAGCTTTTAAATCAGTGGCACGCTTTGGATAAAAGCGCGAAATTAAGCGATGAGATTTATCAAACTCAAGC
CAAACGCTTAGAATTGCAAGGGGCTCAAAACATTTTAAAAACCACGATTGGGATTTTCCAAAAAGACAGCGATGAGGCTA
TAAGCATCGTTAAATCTCAAGTTAAAAACCAGCTTTTTAAATTGGTTTATGTGTTTTTAGCAGCCCTTTTGAGCGTGGTG
TTTGCTTGGATTTTAAAAATCATTTCCAGTAAATACATTGAAAATAATGAGCGCGTCTATACCGTGAATAAAGCCATTAA
CTTCGTGAATGTGAGCGTGATCATTTTAATCTTTCTTTTTTCTTACTTAGAAAATGTTACTTACTTGGTCACGGTTTTAG
GCTTTGCGAGCGCGGGCTTAGCGATTGCGATGAAAGATTTGTTCATGAGCTTGCTTGGGTGGTTTATTATTTTGATTGGG
GGGAGCGTGCATGTGGGCGATAGGGTGCGTATCGCTAAGGGGACGGATATTTTTATTGGCGATGTGTTGGATATTTCTAT
GTTGCACATTACGATTTTAGAAGATGTAACCTTTACCACTTATACGAACAACAGGAGAGCGGGCCGGATTATTTTTGTGC
CTAATAATTACATTTTCACCACCATGTTCGCTAATTACAGCCATTTTGGGATGAAAACGGTTTGGGATGGGGTGGATTTT
TGCGTTACATTTGATTCTGATTTTAAAAAAGCTTCTAAAATTGCACTCAATATCGCTACAGAATTGTCTAAAGAATACAC
GGATATTACCTACAAACAGCTCAATAAAATGCGCGACCGGTATTCTTTAAGGAGTTTGAGCGTGAAGCCTCGGTGCTTTT
TGATGCCTGAAAGTAACGGGATAAAAATCTCGGTGTGGTATCAAACCAATTCGTATGCAACCTTGTCTTTAAGGAGCAAG
ATTGTGGCTGAAATTGTTGAAGCTTTTTTGAAAGAAGAAAATATCCATATCGCTTATACGACCAGCAAGCTGCTTAAAGT
GGATACTGAAGGCGATGGCTTTGGGAATAAAAGGGAACAAAAATGA

Upstream 100 bases:

>100_bases
GCGAGGATAAGACAATCAAATTCATTCTGCCCAAAGGCGTTGGAGCGTTTGAAATTGCCTCTCATATCCCTAAAGAAACG
ATCATAAAGGTGTTAGAAAA

Downstream 100 bases:

>100_bases
AAAAAGTCTATTTCAAAACTTTTGGGTGCAGGACGAATCTTTTTGACACGCAAGTGATGGGCGAGAATTTGAAGGATTTT
AGCGCGACCTTAGAAGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MALRVLLFFCFLFLQAEDKSQELLTIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKNKKSKDLL
KISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHESLKNNQTALEEVLRLLD
QKHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLVYVFLAALLSVV
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIG
GSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDF
CVTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPESNGIKISVWYQTNSYATLSLRSK
IVAEIVEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKREQK

Sequences:

>Translated_521_residues
MALRVLLFFCFLFLQAEDKSQELLTIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKNKKSKDLL
KISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHESLKNNQTALEEVLRLLD
QKHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLVYVFLAALLSVV
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIG
GSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDF
CVTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPESNGIKISVWYQTNSYATLSLRSK
IVAEIVEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKREQK
>Mature_520_residues
ALRVLLFFCFLFLQAEDKSQELLTIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKNKKSKDLLK
ISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHESLKNNQTALEEVLRLLDQ
KHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLVYVFLAALLSVVF
AWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIGG
SVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDFC
VTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPESNGIKISVWYQTNSYATLSLRSKI
VAEIVEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKREQK

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 59948; Mature: 59816

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRVLLFFCFLFLQAEDKSQELLTIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTE
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHH
KESVRQELRRLKNKKSKDLLKISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
NIANPIAIIDGISFIKSMRLKHESLKNNQTALEEVLRLLDQKHQLLNQWHALDKSAKLSD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLVYVFLAALLSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGL
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AIAMKDLFMSLLGWFIILIGGSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTT
HHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCEEEEECHHHHHHHHHHHHHCCEEEE
YTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFDSDFKKASKIALNIAT
EECCCCCCEEEEECCCEEEEEEECCCHHCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHH
ELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPESNGIKISVWYQTNSYATLSLRSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEHHHHHH
IVAEIVEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKREQK
HHHHHHHHHHCCCCEEEEEEECEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
ALRVLLFFCFLFLQAEDKSQELLTIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHH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HHHHHHHHHHCCCCEEEEEEECEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]