Click here to switch to the map view.

The map label for this gene is yleA [C]

Identifier: 188527091

GI number: 188527091

Start: 278941

End: 280197

Strand: Direct

Name: yleA [C]

Synonym: HPSH_01480

Alternate gene names: 188527091

Gene position: 278941-280197 (Clockwise)

Preceding gene: 188527090

Following gene: 188527092

Centisome position: 17.34

GC content: 39.22

Gene sequence:

>1257_bases
ATGAAAAAAGTCTATTTCAAAACTTTTGGGTGCAGGACGAATCTTTTTGACACGCAAGTGATGGGCGAGAATTTGAAGGA
TTTTAGCGCGACCTTAGAAGAACAAGAAGCCGATATTATTATCATCAATTCTTGCACCGTAACCAATGGGGCCGATAGCG
CAGTAAGGAGTTACGCTAAAAAAATGGCGCGATTAAATAAGGAAGTGCTATTTACTGGCTGTGGGGTGAAAACCCAAGGC
AAGGAGCTTTTTGAAAAAGGGTTTTTAAAGGGCGTTTTTGGGCATGACAATAAAGAAAAGATTAACGCGCTTTTACAAGA
AAAAAAGCGTTTTTTTATAGACGACAATTTAGAAAACAAGCACTTAGACACCACGATGGTGAGCGAGTTTGTGGGAAAAA
CTAGGGCGTTTATTAAGATCCAAGAAGGCTGTGATTTTGATTGCAATTATTGCATTATCCCAAGCGTGAGAGGGAGGGCT
AGGAGTTTTGAAGAGAGGAAAATTTTAGAGCAAGTGGGCCTTTTATGTTCTAAAGGGGTTCAAGAAGTGGTTTTAACCGG
CACCAATGTGGGGAGCTATGGGAAAGATAAAGGAAGCAATATCGCAAGATTGATTAAAAAATTAAGCCAGATTACTGGGT
TAAAGCGCATCAGAATTGGGAGCTTAGAGCCTAATCAAATCAACGATGAATTTTTAGAGCTTTTAGAAGAGGATTTTTTA
GAAAAACATTTGCATATCGCTTTACAGCACAGCCATGATTTCATGCTAGAAAAGATGAACAGAAGAAACCGCACAAAAAG
CGATAGGGAATTATTAGAGGTAATCGCTTCTAAGAATTTTGCTATCGGCACGGATTTTATTGTAGGGCATCCGGGCGAGA
GCGGAAGCGTTTTTGAAGAAGCGTTTAAAAATTTAGAAAGCTTGCCCTTAACGCACATCCACCCTTTTATTTACAGCAAA
CGGAAAGACACCCCCTCTAGTTTGATGACTGATAGCGTGATCTTGGAAGATTCTAAAAAGCGTTTGAATGCGATTAAAGA
TTTGATTTTGCATAAAAATAAGGCGTTCAGGCAATTGCAACTCAAGCTCAATACGCCCCTAAAAGCCTTAGTGGAAGCGC
AAAAAGACGGCGAATTTAAAGCCTTAGATCAATTCTTCAACCCCATTAAAATCAAAAGCGATAAGCCTTTAAGGGCTAGT
TTTTTAGAAATTAGGGATTATGAAATTAAGGAGAGGGAAAACCATGCCGTTTTCTAA

Upstream 100 bases:

>100_bases
CTTTTTTGAAAGAAGAAAATATCCATATCGCTTATACGACCAGCAAGCTGCTTAAAGTGGATACTGAAGGCGATGGCTTT
GGGAATAAAAGGGAACAAAA

Downstream 100 bases:

>100_bases
AAATTTAGAAAACCTCACCGCTCCCTTTAAACGCATCAAAAACCGCTCGCTTGTTTTGGCGTTAGGGTTTTTGATCCTTA
CTTTTTGCTTGCTTCTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIIINSCTVTNGADSAVRSYAKKMARLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDKGSNIARLIKKLSQITGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLEKMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESGSVFEEAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVILEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIRDYEIKERENHAVF

Sequences:

>Translated_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIIINSCTVTNGADSAVRSYAKKMARLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDKGSNIARLIKKLSQITGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLEKMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESGSVFEEAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVILEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIRDYEIKERENHAVF
>Mature_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIIINSCTVTNGADSAVRSYAKKMARLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDKGSNIARLIKKLSQITGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLEKMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESGSVFEEAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVILEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIRDYEIKERENHAVF

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=433, Percent_Identity=27.0207852193995, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI28872782, Length=369, Percent_Identity=26.5582655826558, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI28872784, Length=369, Percent_Identity=26.5582655826558, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1786882, Length=395, Percent_Identity=27.8481012658228, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787057, Length=369, Percent_Identity=25.4742547425474, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17553146, Length=408, Percent_Identity=25, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71996771, Length=220, Percent_Identity=26.8181818181818, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21356207, Length=368, Percent_Identity=27.9891304347826, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI19922432, Length=365, Percent_Identity=26.3013698630137, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47748; Mature: 47748

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS01305 MOAA_NIFB_PQQE ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIIINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHH
KMARLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENK
HHHHCCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCSKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
QEVVLTGTNVGSYGKDKGSNIARLIKKLSQITGLKRIRIGSLEPNQINDEFLELLEEDFL
HHEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLEKMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESGSVFEE
HHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCCHHHHH
AFKNLESLPLTHIHPFIYSKRKDTPSSLMTDSVILEDSKKRLNAIKDLILHKNKAFRQLQ
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LKLNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRASFLEIRDYEIKERENHAVF
HHHCCCHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIIINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHH
KMARLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENK
HHHHCCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCSKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
QEVVLTGTNVGSYGKDKGSNIARLIKKLSQITGLKRIRIGSLEPNQINDEFLELLEEDFL
HHEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLEKMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESGSVFEE
HHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCCHHHHH
AFKNLESLPLTHIHPFIYSKRKDTPSSLMTDSVILEDSKKRLNAIKDLILHKNKAFRQLQ
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LKLNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRASFLEIRDYEIKERENHAVF
HHHCCCHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]