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The map label for this gene is aroB

Identifier: 188527089

GI number: 188527089

Start: 276357

End: 277388

Strand: Direct

Name: aroB

Synonym: HPSH_01470

Alternate gene names: 188527089

Gene position: 276357-277388 (Clockwise)

Preceding gene: 188527088

Following gene: 188527090

Centisome position: 17.18

GC content: 37.79

Gene sequence:

>1032_bases
ATGCAAGAAATTTTAATCCCTTTAAAAGAAAAAAGCTATAAAGTGTTTTTGGGGGAACTGCCTGAAATTGAATTGAAACA
AAAAGCGCTCATCATTAGCGATAGCATCGTGGCCGGGTTGCATTTATCGTATTTATTAAAGCGCTTGAAAGCCTTAGAAG
TGAGAGTGTGCGTGATAGAGTCCGGAGAAAAATACAAGAATCTTAATTCATTAGAGTGCATTTTAAACAGCGCCTTTGAA
ATGCAATTAAACCGCCATTCTTTAATGATAGCCCTTGGTGGGGGAGTGATAAGCGATATGGTGGGGTTTGCGAGCAGTAT
TTATTTTAGGGGGATTGATTTTATTAATATCCCTACGACCTTACTCGCTCAAGTGGATGCGAGCGTGGGGGGGAAAACAG
GGATCAATACGCCTTATGGCAAGAATTTAATCGGATCGTTTTACCAGCCTAAAGCGGTTTATATTGATCTGGCTTTTTTA
AAAACCCTTGAAAAAAGGGAATTTCAAGCAGGGGTTGCTGAAATCATTAAAATGGCGGTGTGTTTTGATAAAAACCTGGT
AGAAATATTAGAAACAAGGGATTTAAAAGATTGTTTAGAAGAAGTGGTTTTTCAAAGCGTCAGTATCAAAGCTCAAGTCG
TTACGCAAGATGAAAAAGAGCAAAATATCAGGGCTGGGCTCAATTACGGGCATACCTTTGGGCATGCGATAGAAAAAGAG
ACTGATTATGAGCGATTTTTGCATGGCGAAGCGATCGCTATTGGCATGCACATGGCTAATGATTTAGCCCTTTCTTTAGG
CATGCTCACTCTAAAAGAATACGAACGCATAGAAGATTTATTGAAAAAATTTGATTTGATATTTAATTACAAAATCACAG
ATATTCAAAAATTTTACGAACGCTTGTTTTTAGACAAAAAAAGCGAGGATAAGACAATCAAATTCATTCTGCCCAAAGGC
GTTGGAGCGTTTGAAATTGCCTCTCATATCCCTAAAGAAACGATCATAAAGGTGTTAGAAAAATGGCATTAA

Upstream 100 bases:

>100_bases
CACACGCGCTTTTGGTGGTTTTTATCCACTAAAGTGGAAAAATTAGCGTTTTTAAACGATGATAACCCTCAAATTTTTAT
CCCCATAGCGGAGTGAAAGA

Downstream 100 bases:

>100_bases
GGGTATTATTATTCTTTTGTTTTTTGTTTTTACAAGCAGAAGATAAAAGCCAAGAACTATTGACCATACAAAAACAAATG
GCTTTGGTGGATAAAAAACT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQEILIPLKEKSYKVFLGELPEIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNLNSLECILNSAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKNLVEILETRDLKDCLEEVVFQSVSIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMHMANDLALSLGMLTLKEYERIEDLLKKFDLIFNYKITDIQKFYERLFLDKKSEDKTIKFILPKG
VGAFEIASHIPKETIIKVLEKWH

Sequences:

>Translated_343_residues
MQEILIPLKEKSYKVFLGELPEIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNLNSLECILNSAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKNLVEILETRDLKDCLEEVVFQSVSIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMHMANDLALSLGMLTLKEYERIEDLLKKFDLIFNYKITDIQKFYERLFLDKKSEDKTIKFILPKG
VGAFEIASHIPKETIIKVLEKWH
>Mature_343_residues
MQEILIPLKEKSYKVFLGELPEIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNLNSLECILNSAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKNLVEILETRDLKDCLEEVVFQSVSIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMHMANDLALSLGMLTLKEYERIEDLLKKFDLIFNYKITDIQKFYERLFLDKKSEDKTIKFILPKG
VGAFEIASHIPKETIIKVLEKWH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=357, Percent_Identity=36.9747899159664, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=284, Percent_Identity=34.8591549295775, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38862; Mature: 38862

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEILIPLKEKSYKVFLGELPEIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIE
CCCCEEECCCCCEEEEECCCCCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEE
SGEKYKNLNSLECILNSAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTT
CCHHHCCCHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCHH
LLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYIDLAFLKTLEKREFQAGVAEIIKMAV
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CFDKNLVEILETRDLKDCLEEVVFQSVSIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
HHCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCHHHHHHCCC
TDYERFLHGEAIAIGMHMANDLALSLGMLTLKEYERIEDLLKKFDLIFNYKITDIQKFYE
CCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RLFLDKKSEDKTIKFILPKGVGAFEIASHIPKETIIKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MQEILIPLKEKSYKVFLGELPEIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIE
CCCCEEECCCCCEEEEECCCCCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEE
SGEKYKNLNSLECILNSAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTT
CCHHHCCCHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCHH
LLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYIDLAFLKTLEKREFQAGVAEIIKMAV
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CFDKNLVEILETRDLKDCLEEVVFQSVSIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
HHCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCHHHHHHCCC
TDYERFLHGEAIAIGMHMANDLALSLGMLTLKEYERIEDLLKKFDLIFNYKITDIQKFYE
CCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RLFLDKKSEDKTIKFILPKGVGAFEIASHIPKETIIKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA