Click here to switch to the map view.

The map label for this gene is mtaD [H]

Identifier: 188527073

GI number: 188527073

Start: 262055

End: 263284

Strand: Direct

Name: mtaD [H]

Synonym: HPSH_01390

Alternate gene names: 188527073

Gene position: 262055-263284 (Clockwise)

Preceding gene: 188527072

Following gene: 188527074

Centisome position: 16.29

GC content: 39.76

Gene sequence:

>1230_bases
ATGCAAGAAATCATAGGAGCGTCTTTAGTTTTTTTATGCAATGAAAAATGCGAAGTGTTAGAAGATTATGGCGTGGTCTT
TGATGAAAAGATTGTTGAAGTGGGCGATTATAAAAGTTTAACGCTTAAATACCCCCACTTAAAGGCGCAGTTTTTTGAAA
ATTCCGTTCTGTTGCCCGCTTTTATCAACGCGCACACCCATTTTGAATTTTCCAACAATAAGGCGAGTTTTGATTACGGG
AGTTTTTCTGGCTGGTTAGGGAGCGTGTTAAACAATGGGGGGGCGATTTTAGAAAATTGCCAAGGGGCTATTCAAAACGC
TATCATTACGCAATTAAAAAGCGGGGTAGGGAGCGTGGGAGCGATTTCTAACCACCTGATAGAAGTTAATTTGTTAAAAG
AAAGCCCTTTGAACGCTGTCGTGTTTTTAGAGTTTTTAGGGAGTAGCTATTCTTTAGAAAAACTAAAAGCGTTTGAGGCA
AAATTCAAAGAGTTAAAAGATTTAGAAGACAAAAAGCTTAAAGTCGCTCTCGCTGTGCATGCCCCTTATTCGGTCCAAAA
AGACATGGCTTTAAGCGTCATCCAATTAGCCAAAGATTCACAAAGCCTGCTTTCTACGCATTTTTTAGAATCGTTTGAAG
AGTTAGAATGGGTAGAAAACTCTAAAGGGTGGTTTGAAAATTTTTACCAGCATTTTTTAAAGGAGTCTCATTTCAAATCG
CTCTATAAGGGCGCAAACGACTACATTGACATGTTTAAAGACACACACACTTTATTCGTGCATAACCAGTTCGCTTCTTT
GGAGGTGTTAAAAAGGATTAAATCTCAAGTCAAAAACGCTTTTTTAATCACATGCCCCTTTTCTAACCGCCTATTGAGCG
GGCAAGCGTTGGATTTAGAAAGAACCAAAGAGGCCGGTTTGAGCGTGAGCGTGGCCACTGATGGCTTGAGTTCTAACATT
TCGCTAAGCCTTTTAGACGAATTAAGAGCGTTCTTGCTCACCCATAACATGCCGTTATTAAAATTAGCTAAGATCGCTCT
TTTAGGAGCGACTAGGCATGGGGCTAAAGCTTTAGCCTTAAATAATGGCGAGATAGAAGCCAATAAGAGGGCGGATTTGA
GCGTGTTTAATTTTGGTGAAAAATTCATTAAAGAGCAAGCGGTTTTGCAATTTTTATTGCATGCTAAAGAAGTGGAGTGC
TTGTTTTTGGGGGGGAAAAGGGTGATCTAA

Upstream 100 bases:

>100_bases
GAGTTATTAATAAAAATTCGCCCTTTTATGGTTTAGAATTATATGGCGAAGTTCAAAGAATGATCTTAAAAGGGCAAACC
ACATTGATTAAGGAGAATGC

Downstream 100 bases:

>100_bases
TTTGTTTTAAAGACAGAATGCGTTAAAATGAGAAATCTAAATCAATTAAGGGAAGAGTCAATGAAATTAGTTTTAGCCAA
GAATACAAGAAAATCAGACG

Product: chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MQEIIGASLVFLCNEKCEVLEDYGVVFDEKIVEVGDYKSLTLKYPHLKAQFFENSVLLPAFINAHTHFEFSNNKASFDYG
SFSGWLGSVLNNGGAILENCQGAIQNAIITQLKSGVGSVGAISNHLIEVNLLKESPLNAVVFLEFLGSSYSLEKLKAFEA
KFKELKDLEDKKLKVALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESHFKS
LYKGANDYIDMFKDTHTLFVHNQFASLEVLKRIKSQVKNAFLITCPFSNRLLSGQALDLERTKEAGLSVSVATDGLSSNI
SLSLLDELRAFLLTHNMPLLKLAKIALLGATRHGAKALALNNGEIEANKRADLSVFNFGEKFIKEQAVLQFLLHAKEVEC
LFLGGKRVI

Sequences:

>Translated_409_residues
MQEIIGASLVFLCNEKCEVLEDYGVVFDEKIVEVGDYKSLTLKYPHLKAQFFENSVLLPAFINAHTHFEFSNNKASFDYG
SFSGWLGSVLNNGGAILENCQGAIQNAIITQLKSGVGSVGAISNHLIEVNLLKESPLNAVVFLEFLGSSYSLEKLKAFEA
KFKELKDLEDKKLKVALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESHFKS
LYKGANDYIDMFKDTHTLFVHNQFASLEVLKRIKSQVKNAFLITCPFSNRLLSGQALDLERTKEAGLSVSVATDGLSSNI
SLSLLDELRAFLLTHNMPLLKLAKIALLGATRHGAKALALNNGEIEANKRADLSVFNFGEKFIKEQAVLQFLLHAKEVEC
LFLGGKRVI
>Mature_409_residues
MQEIIGASLVFLCNEKCEVLEDYGVVFDEKIVEVGDYKSLTLKYPHLKAQFFENSVLLPAFINAHTHFEFSNNKASFDYG
SFSGWLGSVLNNGGAILENCQGAIQNAIITQLKSGVGSVGAISNHLIEVNLLKESPLNAVVFLEFLGSSYSLEKLKAFEA
KFKELKDLEDKKLKVALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESHFKS
LYKGANDYIDMFKDTHTLFVHNQFASLEVLKRIKSQVKNAFLITCPFSNRLLSGQALDLERTKEAGLSVSVATDGLSSNI
SLSLLDELRAFLLTHNMPLLKLAKIALLGATRHGAKALALNNGEIEANKRADLSVFNFGEKFIKEQAVLQFLLHAKEVEC
LFLGGKRVI

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 45641; Mature: 45641

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEIIGASLVFLCNEKCEVLEDYGVVFDEKIVEVGDYKSLTLKYPHLKAQFFENSVLLPA
CCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCHHHHHHCCCEEEHH
FINAHTHFEFSNNKASFDYGSFSGWLGSVLNNGGAILENCQGAIQNAIITQLKSGVGSVG
HHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
AISNHLIEVNLLKESPLNAVVFLEFLGSSYSLEKLKAFEAKFKELKDLEDKKLKVALAVH
HHHCCEEEEEEECCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
APYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESHFKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LYKGANDYIDMFKDTHTLFVHNQFASLEVLKRIKSQVKNAFLITCPFSNRLLSGQALDLE
HHCCCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHH
RTKEAGLSVSVATDGLSSNISLSLLDELRAFLLTHNMPLLKLAKIALLGATRHGAKALAL
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEE
NNGEIEANKRADLSVFNFGEKFIKEQAVLQFLLHAKEVECLFLGGKRVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MQEIIGASLVFLCNEKCEVLEDYGVVFDEKIVEVGDYKSLTLKYPHLKAQFFENSVLLPA
CCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCHHHHHHCCCEEEHH
FINAHTHFEFSNNKASFDYGSFSGWLGSVLNNGGAILENCQGAIQNAIITQLKSGVGSVG
HHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
AISNHLIEVNLLKESPLNAVVFLEFLGSSYSLEKLKAFEAKFKELKDLEDKKLKVALAVH
HHHCCEEEEEEECCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
APYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESHFKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LYKGANDYIDMFKDTHTLFVHNQFASLEVLKRIKSQVKNAFLITCPFSNRLLSGQALDLE
HHCCCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHH
RTKEAGLSVSVATDGLSSNISLSLLDELRAFLLTHNMPLLKLAKIALLGATRHGAKALAL
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEE
NNGEIEANKRADLSVFNFGEKFIKEQAVLQFLLHAKEVECLFLGGKRVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA