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The map label for this gene is radA [H]

Identifier: 188527028

GI number: 188527028

Start: 215972

End: 217318

Strand: Direct

Name: radA [H]

Synonym: HPSH_01155

Alternate gene names: 188527028

Gene position: 215972-217318 (Clockwise)

Preceding gene: 188527027

Following gene: 188527029

Centisome position: 13.43

GC content: 43.06

Gene sequence:

>1347_bases
TTGGCTAAAAAAACTTCTTTATTTGAGTGTCAGCATTGCGGTTTTACAAGCCCTAAGTGGCTAGGCAAGTGCGTTCAATG
CAACGCATGGGAAAGTTTTATAGAATTGAACCAAACCCAAAAGGAAGTTTTAAACACGCTTAAAAACCCGATCCCAAAAG
CGCAAAAAAGCGTTTCTATCGCTGAAATTGAACATGAAGAAGTGATCAAGTTTTCTTCCACTCAAAGCGAGTTGGATATT
GTTTTAGGTGGGGGGATTGCTAAAGGAGGGTTGTATTTGGTGGGGGGGAGTCCTGGGGTGGGGAAATCCACTCTGCTTTT
AAAAGTGGCTTCTGGCTTAGCCAAAAATCAGCAAAAGGTTTTGTATGTGAGCGGGGAAGAGAGCTTGAGCCAGATTAAAA
TGCGTGCCACTAGATTGGATTGCATAGAAAAAGAATTGTATCTGCTCAATGAAATCAACTGGCCTGTGATTAAGGCGAAT
ATTGAAAGCGAAAATTATTTTGCTTGCGTGATTGATTCCATTCAAACGCTTTATTCGCCAGAGATTTCTTCAGCGCCCGG
CTCTATTTCGCAAGTGCGAGAGATCACTTTTGAGCTCATGCGTTTAGCCAAAACAAGAAATATTGCTGTTTTTATCATCG
GTCATATCACTAAAGAAGGGAGCATCGCAGGGCCTAGAGTGCTAGAGCATATGGTGGATAGCGTGCTGTATTTTGAAGGC
GATCCCAGTAGGGAGTTAAGGATTTTAAGGAGTTTTAAAAACCGCTTTGGCCCTACGAGTGAAATCGGCTTGTTTGAAAT
GAAAGAGCAGGGTTTGGTGAGCGCTAAAGAAGCTTCAAGCTTGTTTTTTTCTCAAGAAGAGCCTATGGAGGGGAGCGCGA
TCACCATCACTTTAGAAGGCTCAAGGGCGTTGATTTTAGAAATCCAGGCGTTGGTGAGCGAGTGCAGTTTCGGAGCGCCC
AAACGATTAGCGAACGGGTTTGACACCAACCGCCTTAACATGCTCATCGCTTTATTAGAAAAAAAGCTAGAAATCCCCTT
AAACCGCCATGATGTGTTCATTAATGTGAGCGGAGGCATTAAGATTAGCGAGCCGGCTTGCGATTTAGCGGTCATTGCCA
GTATCCTTTCAAGCTTTAAAAACAGAAAAATTGACAATAAAACGGCGTTTTTGGGCGAAGTGAGTTTGAATGGCAGGATC
TTAGAAGCCCCTAATTTGAACGCCAGATTGAAAGAAATGGAAAATTACGGCTTTTTAAAAGCCATTTTGCCTAAAAAACC
CAGCCAAAAAACCTCGATCAAATGCTATGAGGCCAATGCGGTGGGCAAGATTGTTGAATGGATGTGA

Upstream 100 bases:

>100_bases
TTGTTTTTTAGTTTAGCTCCACGAGTTTTGCTACAGAACAAAACTAAAGCCCCATTTTTATTTAGTATTTAGCTGTGTGG
TTTTAAAAAAGAGGGATATT

Downstream 100 bases:

>100_bases
ATAGGATTAAGCGATTTAAAAAGCAATTATTACTTTTTTAGCTTATAATTGCTATCATTATTGAAATAAAGGTTATTTAA
TGAAAGTATTATCTTACTTG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNTLKNPIPKAQKSVSIAEIEHEEVIKFSSTQSELDI
VLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKAN
IESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAVFIIGHITKEGSIAGPRVLEHMVDSVLYFEG
DPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSQEEPMEGSAITITLEGSRALILEIQALVSECSFGAP
KRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRI
LEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM

Sequences:

>Translated_448_residues
MAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNTLKNPIPKAQKSVSIAEIEHEEVIKFSSTQSELDI
VLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKAN
IESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAVFIIGHITKEGSIAGPRVLEHMVDSVLYFEG
DPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSQEEPMEGSAITITLEGSRALILEIQALVSECSFGAP
KRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRI
LEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM
>Mature_447_residues
AKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNTLKNPIPKAQKSVSIAEIEHEEVIKFSSTQSELDIV
LGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKANI
ESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRNIAVFIIGHITKEGSIAGPRVLEHMVDSVLYFEGD
PSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSQEEPMEGSAITITLEGSRALILEIQALVSECSFGAPK
RLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRIL
EAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=426, Percent_Identity=41.0798122065728, Blast_Score=337, Evalue=7e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49483; Mature: 49352

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNTLKNPIPKAQKSVSI
CCCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHCCCCHHHHCCCH
AEIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKV
HHCCHHHHHEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEE
LYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKANIESENYFACVIDSIQTLYSP
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHHHCCC
EISSAPGSISQVREITFELMRLAKTRNIAVFIIGHITKEGSIAGPRVLEHMVDSVLYFEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHEEEECC
DPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSQEEPMEGSAITITLEG
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
SRALILEIQALVSECSFGAPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGI
CCEEEHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCE
KISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKEMENYGFLK
EECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHCCCCEE
AILPKKPSQKTSIKCYEANAVGKIVEWM
ECCCCCCCCCCEEEEEECCCHHHHHHCC
>Mature Secondary Structure 
AKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNTLKNPIPKAQKSVSI
CCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHCCCCHHHHCCCH
AEIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKV
HHCCHHHHHEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEE
LYVSGEESLSQIKMRATRLDCIEKELYLLNEINWPVIKANIESENYFACVIDSIQTLYSP
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHHHCCC
EISSAPGSISQVREITFELMRLAKTRNIAVFIIGHITKEGSIAGPRVLEHMVDSVLYFEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHEEEECC
DPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSQEEPMEGSAITITLEG
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
SRALILEIQALVSECSFGAPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGI
CCEEEHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCE
KISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKEMENYGFLK
EECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHCCCCEE
AILPKKPSQKTSIKCYEANAVGKIVEWM
ECCCCCCCCCCEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]