Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 187928903

GI number: 187928903

Start: 1913941

End: 1914435

Strand: Reverse

Name: arsC [H]

Synonym: Rpic_1821

Alternate gene names: 187928903

Gene position: 1914435-1913941 (Counterclockwise)

Preceding gene: 187928904

Following gene: 187928902

Centisome position: 48.56

GC content: 63.03

Gene sequence:

>495_bases
ATGGCCGACAAGACCTACAACGTGCTATTCATCTGCACTGGCAACTCCGCGCGCTCGATCTTGGCTGAGGGCCTGCTGAA
CCATCTCGGTGGCAACCGCTTCAAGGCGTTCTCCGCAGGCAGTCATCCGGCCGGGACGGTGAACCCGTTTGCCCTGCGCG
CGTTGCAGCAGTTCGGCGTTGCGACCGACGGCTTCCGCAGCAAGAGCTGGGATGAGTTCTCGCAAGACGGTGCGCCCGAG
TTGGACTTCGTTTTCACCGTCTGCGACAAGGCGGCCGGCGAGGCGTGTCCGGTGTGGCCCGGCCAGCCGATGACCGCCCA
TTGGGGTGTGGCTGATCCCGCAGCGGTGGAAGGCTCAAACGAGCGCAAGCAGCAGGCCATCCGCGATGCGGCGATTACCC
TGAAGCGCCGCATAGAGTTGTTCCTCTCGTTGCCAATCCCGAAGCTCGATACCGTGGCCCTGCAAAAGGCTGTGCACGAC
ATCGGCCAGCAATAA

Upstream 100 bases:

>100_bases
GCGACCGAAGGCTCCGCCTGCTGCGCCCCACGCGCGCCGGGCGGAAAGCCGACCGGCATTGCGGTGAAGTCCGGTTCGTC
CTGCTGCTAGGAGGGCCGTG

Downstream 100 bases:

>100_bases
CCTCTCTCTCCCATGACCACTAACGTACTGATCCTCTGCACCCACAATTCCGCGCGCAGCGTGCTGAGCGAAGGCATGCT
CAACCACTGGGCGCAAGAGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MADKTYNVLFICTGNSARSILAEGLLNHLGGNRFKAFSAGSHPAGTVNPFALRALQQFGVATDGFRSKSWDEFSQDGAPE
LDFVFTVCDKAAGEACPVWPGQPMTAHWGVADPAAVEGSNERKQQAIRDAAITLKRRIELFLSLPIPKLDTVALQKAVHD
IGQQ

Sequences:

>Translated_164_residues
MADKTYNVLFICTGNSARSILAEGLLNHLGGNRFKAFSAGSHPAGTVNPFALRALQQFGVATDGFRSKSWDEFSQDGAPE
LDFVFTVCDKAAGEACPVWPGQPMTAHWGVADPAAVEGSNERKQQAIRDAAITLKRRIELFLSLPIPKLDTVALQKAVHD
IGQQ
>Mature_163_residues
ADKTYNVLFICTGNSARSILAEGLLNHLGGNRFKAFSAGSHPAGTVNPFALRALQQFGVATDGFRSKSWDEFSQDGAPEL
DFVFTVCDKAAGEACPVWPGQPMTAHWGVADPAAVEGSNERKQQAIRDAAITLKRRIELFLSLPIPKLDTVALQKAVHDI
GQQ

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17696; Mature: 17565

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKTYNVLFICTGNSARSILAEGLLNHLGGNRFKAFSAGSHPAGTVNPFALRALQQFGV
CCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCC
ATDGFRSKSWDEFSQDGAPELDFVFTVCDKAAGEACPVWPGQPMTAHWGVADPAAVEGSN
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCC
ERKQQAIRDAAITLKRRIELFLSLPIPKLDTVALQKAVHDIGQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADKTYNVLFICTGNSARSILAEGLLNHLGGNRFKAFSAGSHPAGTVNPFALRALQQFGV
CCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCC
ATDGFRSKSWDEFSQDGAPELDFVFTVCDKAAGEACPVWPGQPMTAHWGVADPAAVEGSN
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCC
ERKQQAIRDAAITLKRRIELFLSLPIPKLDTVALQKAVHDIGQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]