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The map label for this gene is arsC [H]

Identifier: 187928902

GI number: 187928902

Start: 1913434

End: 1913928

Strand: Reverse

Name: arsC [H]

Synonym: Rpic_1820

Alternate gene names: 187928902

Gene position: 1913928-1913434 (Counterclockwise)

Preceding gene: 187928903

Following gene: 187928901

Centisome position: 48.55

GC content: 64.65

Gene sequence:

>495_bases
ATGACCACTAACGTACTGATCCTCTGCACCCACAATTCCGCGCGCAGCGTGCTGAGCGAAGGCATGCTCAACCACTGGGC
GCAAGAGCTGGGCAAGGACGTGCGCGCCTACAGCGCCGGCAGCGCACCCAGCGGCCGTCTCAACCCGTTCGCGCTGGAAG
CGCTCACCAACTCCGACATCGACATCACCGGCTACCGCAGCAAGAGCTGGGATGAGTTCGTCGTGGACGGTGCGCCGCAG
ATGCGCATCGTGATCACCGTGTGCGACAGCGCCGCCGCCGAGCAATGTCCCTATTGGCCGGGCAGCCCGGTCAAGGTGCA
CTGGGGCTACGCTGATCCGTCCAACGCGCCGGGTGGAGATGACGGCAAACGCCAAGCCTTCGAGCTGACGCGCCAGGCGA
TCGGCTACCGCATGCTGCAACTGCTGGCGTTGCCGCTCGACACCCTGAACAACGCCGAGCTGCAAGCGCAGCTCGAACAC
ATCTCGCAAGACTGA

Upstream 100 bases:

>100_bases
CCGCATAGAGTTGTTCCTCTCGTTGCCAATCCCGAAGCTCGATACCGTGGCCCTGCAAAAGGCTGTGCACGACATCGGCC
AGCAATAACCTCTCTCTCCC

Downstream 100 bases:

>100_bases
ACGCCATGGTCGATCTGCGCAGCCGGCTTGCCGCCGAAGCACTGGGCACGGCGCTACTGCTCGCCATTGTCATCGGGTCC
GGCATCATGGCCGAACGCCT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTTNVLILCTHNSARSVLSEGMLNHWAQELGKDVRAYSAGSAPSGRLNPFALEALTNSDIDITGYRSKSWDEFVVDGAPQ
MRIVITVCDSAAAEQCPYWPGSPVKVHWGYADPSNAPGGDDGKRQAFELTRQAIGYRMLQLLALPLDTLNNAELQAQLEH
ISQD

Sequences:

>Translated_164_residues
MTTNVLILCTHNSARSVLSEGMLNHWAQELGKDVRAYSAGSAPSGRLNPFALEALTNSDIDITGYRSKSWDEFVVDGAPQ
MRIVITVCDSAAAEQCPYWPGSPVKVHWGYADPSNAPGGDDGKRQAFELTRQAIGYRMLQLLALPLDTLNNAELQAQLEH
ISQD
>Mature_163_residues
TTNVLILCTHNSARSVLSEGMLNHWAQELGKDVRAYSAGSAPSGRLNPFALEALTNSDIDITGYRSKSWDEFVVDGAPQM
RIVITVCDSAAAEQCPYWPGSPVKVHWGYADPSNAPGGDDGKRQAFELTRQAIGYRMLQLLALPLDTLNNAELQAQLEHI
SQD

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17917; Mature: 17786

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNVLILCTHNSARSVLSEGMLNHWAQELGKDVRAYSAGSAPSGRLNPFALEALTNSDI
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
DITGYRSKSWDEFVVDGAPQMRIVITVCDSAAAEQCPYWPGSPVKVHWGYADPSNAPGGD
EEEECCCCCCCHHEECCCCCEEEEEEECCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
DGKRQAFELTRQAIGYRMLQLLALPLDTLNNAELQAQLEHISQD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTNVLILCTHNSARSVLSEGMLNHWAQELGKDVRAYSAGSAPSGRLNPFALEALTNSDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
DITGYRSKSWDEFVVDGAPQMRIVITVCDSAAAEQCPYWPGSPVKVHWGYADPSNAPGGD
EEEECCCCCCCHHEECCCCCEEEEEEECCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
DGKRQAFELTRQAIGYRMLQLLALPLDTLNNAELQAQLEHISQD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA