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The map label for this gene is lpxA [H]

Identifier: 187927731

GI number: 187927731

Start: 675801

End: 676568

Strand: Reverse

Name: lpxA [H]

Synonym: Rpic_0635

Alternate gene names: 187927731

Gene position: 676568-675801 (Counterclockwise)

Preceding gene: 187927732

Following gene: 187927730

Centisome position: 17.16

GC content: 55.47

Gene sequence:

>768_bases
ATGATTCATCCCACTGCTATCGTTTCGCCCGAAGCCCGTATTGGGGCCAATGTTTCGATCGGGCCGTTCAGTGTGATCCA
CTCCAACGTCGAAATCGGCGAAGGTACACAGATCGAAGGATTCTGCGAGATCGGACATCCAAGCAAGCTGTCCGACGGAC
AGCCGCTGTGCATTGGCAAGGACTCCTTGATACGGTCTCACAGTGTCTTTTACGAGGGTTCGTCGTTTGGAGAACGGTTG
GTAACCGGGCATCGGGTTACGGTGCGCGAGATGACACGCTGTGGAGTCAACTTCCAACTCGGGACGTTGAGCGACATCCA
GGGACATTGCGTCATCGGGGACTACGTCCGCACGCACAGCAACGTGCACATCGGGCAGGCGTCGCGAGTTGGGGATTTCG
TATGGATTTTTCCATATGTTGTGCTGACCAACGATCCACACCCCCCTAGCAATGTCCTGAAGGGATGCGTGCTGGAAGAC
TACGCGGTAGTTGCAACGATGTCAGTCGTACTACCGGCCGTCACAGTCGGCTCGCATTCGCTTGTCGCCGCACACAGTCT
CGTTTCTAAGAATGTGACACCGCATACCGTCGTCGGCGGATCTCCAGCAAAGATGCTGTGTGAAACTAGCAAAATTAAGC
TTCAAGACGGAACCGATCGACCGGCATATCCTTGGACTTCACACTTCCACCGCGGCTATCCAGAGACCGTGGTAGCGAAT
TGGATAGAAGCAGCCAACGCGCTCGCCAACACGCAGTGCGCCCGGTAA

Upstream 100 bases:

>100_bases
CCCCCGATTGCGTACTGCTCGTGCTGGCAAATAAGATTTACGATCCGGAAGACTACATTCGGGATCACGAAACCTTTGTT
TCGATGACCAAGGAGAGATC

Downstream 100 bases:

>100_bases
GCGTGGCTTAAGGAAATAACAGTAACTGTGCCGAGATTTTATCGATGATTCCGTTTCTCGACCTTAAGAGTATCAATGCG
CGGCAACGAGCCGAATTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIHPTAIVSPEARIGANVSIGPFSVIHSNVEIGEGTQIEGFCEIGHPSKLSDGQPLCIGKDSLIRSHSVFYEGSSFGERL
VTGHRVTVREMTRCGVNFQLGTLSDIQGHCVIGDYVRTHSNVHIGQASRVGDFVWIFPYVVLTNDPHPPSNVLKGCVLED
YAVVATMSVVLPAVTVGSHSLVAAHSLVSKNVTPHTVVGGSPAKMLCETSKIKLQDGTDRPAYPWTSHFHRGYPETVVAN
WIEAANALANTQCAR

Sequences:

>Translated_255_residues
MIHPTAIVSPEARIGANVSIGPFSVIHSNVEIGEGTQIEGFCEIGHPSKLSDGQPLCIGKDSLIRSHSVFYEGSSFGERL
VTGHRVTVREMTRCGVNFQLGTLSDIQGHCVIGDYVRTHSNVHIGQASRVGDFVWIFPYVVLTNDPHPPSNVLKGCVLED
YAVVATMSVVLPAVTVGSHSLVAAHSLVSKNVTPHTVVGGSPAKMLCETSKIKLQDGTDRPAYPWTSHFHRGYPETVVAN
WIEAANALANTQCAR
>Mature_255_residues
MIHPTAIVSPEARIGANVSIGPFSVIHSNVEIGEGTQIEGFCEIGHPSKLSDGQPLCIGKDSLIRSHSVFYEGSSFGERL
VTGHRVTVREMTRCGVNFQLGTLSDIQGHCVIGDYVRTHSNVHIGQASRVGDFVWIFPYVVLTNDPHPPSNVLKGCVLED
YAVVATMSVVLPAVTVGSHSLVAAHSLVSKNVTPHTVVGGSPAKMLCETSKIKLQDGTDRPAYPWTSHFHRGYPETVVAN
WIEAANALANTQCAR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=216, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27418; Mature: 27418

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHPTAIVSPEARIGANVSIGPFSVIHSNVEIGEGTQIEGFCEIGHPSKLSDGQPLCIGK
CCCCCEEECCCHHCCCCCCCCCHHHEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEECC
DSLIRSHSVFYEGSSFGERLVTGHRVTVREMTRCGVNFQLGTLSDIQGHCVIGDYVRTHS
HHHHHHHHEEECCCCHHHHHHCCCEEHHHHHHHCCCCEEECCCCCCCCCEEEEHHHHCCC
NVHIGQASRVGDFVWIFPYVVLTNDPHPPSNVLKGCVLEDYAVVATMSVVLPAVTVGSHS
CEEECCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LVAAHSLVSKNVTPHTVVGGSPAKMLCETSKIKLQDGTDRPAYPWTSHFHRGYPETVVAN
HHHHHHHHHCCCCCCEEECCCHHHHEECCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHH
WIEAANALANTQCAR
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MIHPTAIVSPEARIGANVSIGPFSVIHSNVEIGEGTQIEGFCEIGHPSKLSDGQPLCIGK
CCCCCEEECCCHHCCCCCCCCCHHHEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEECC
DSLIRSHSVFYEGSSFGERLVTGHRVTVREMTRCGVNFQLGTLSDIQGHCVIGDYVRTHS
HHHHHHHHEEECCCCHHHHHHCCCEEHHHHHHHCCCCEEECCCCCCCCCEEEEHHHHCCC
NVHIGQASRVGDFVWIFPYVVLTNDPHPPSNVLKGCVLEDYAVVATMSVVLPAVTVGSHS
CEEECCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LVAAHSLVSKNVTPHTVVGGSPAKMLCETSKIKLQDGTDRPAYPWTSHFHRGYPETVVAN
HHHHHHHHHCCCCCCEEECCCHHHHEECCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHH
WIEAANALANTQCAR
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA