| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is pdxA [H]
Identifier: 187927661
GI number: 187927661
Start: 598044
End: 600356
Strand: Reverse
Name: pdxA [H]
Synonym: Rpic_0564
Alternate gene names: 187927661
Gene position: 600356-598044 (Counterclockwise)
Preceding gene: 187927662
Following gene: 187927660
Centisome position: 15.23
GC content: 68.87
Gene sequence:
>2313_bases GTGAACACGTCCGCCCACACCGCTCCGAAGCTGCTGATCCTGGCCGACGACCTGTCGGGCGCCGCCGATTGCGCGGTGGC CGGCGTGCGGGCCGGATTGCGCAGCGCGGTCATGCTGCGCGCCGATGTTGGACACCCCATCGGGTATCCGACCAGCGCCG ACGTCCTCGCACTGGACACCGACACGCGGCGCGCCAATGCCGTCGATGCGGCGGCCACGCAGGTGGCGGCATGGCATGCA CTGGCCCGGCCGGCCACGCGGCTCTACAAGAAGATCGATTCGACCCTGCGCGGCAACGTCGCTGCTGAGGTGGCCGCGCT TGCACCGCTGGCGGGTCTGGCCATCGTGGCGCCGGCGTTTCCGGCAGCCGGACGCACCACCCGCGACGGCCGCCAGTGGC TGCACGGCGTGGCCGTGGAAGACACCGAGGTGTGGCGCAACGAAAGCATCGGCGGCCGCGCCGATCTGCGCGTCATGTTG GAGCGCCAAGGCCTTCAGACCGCCGTGCTGACGCTTGACGACATCCGCGCCGGTGCCGCCGCGCTGGCCGGTCGCCTGGC GGCACTACAGGCGGACGGTGTGCAAGCCGTGGTGTGCGACGCCCAGACCGATGACGACCTCGCGCACATCGCCGAGACCT CCGTGCGGCTGGCGCATGTGTTCTGGGTCGGCTCCGCCGGTCTGGCGCCCGCGCTGATTCGCGCGGCGGGGCTCGGCAGC GCCAACGCCGCTGTCGAAGGCGATGCGGCAACCGCAATCGCCGGGCCGGTGCTGACGGTGGTGGGCAGCATGTCCAGCGT GTCCCATGCGCAGGCGTCGGAATTGAAGGCCGCTGCCGGTGCGCGCCTGCTGTCGCTGGAGCTGCCCGTGGAAGAGCTCG ACACACCGCAGGCGGACATCACCCAGACCGTCATCGATGCGCTGTGCGAAGGCCGCGACGTGCTGGTCACGCTCAGCCAA ACCACGCGCGGCAACAGCGCCGACGGCCTGCACTTCTGCCGCCGCCTCGCCACGTTGCTGGCGCCGGCTTTGCCGCATGC CGGCGGGCTGATCGCCACCGGCGGCGAGACCGCGCGCGCCGTGCTGTCGACCGCCGGCATCGACGCGCTGCGCCTGTGCG ACGAAATCGAATCCGGCATGCCGCTGCTGCATGCCCAACTTACTGGCGTCGGCGGCGTGCTGCCGGTCGTCACCAAGGCG GGGGGCTTCGGCACACCCGGCTCCCTGCATGCCGCTTGGCGACGGTTGATCGAAACCGCAGCCAGCACCCCACCCAAAGG AACTCACGCAATGACCTATCGTCCTGTCATCGGCATCACCATGGGCGATGCCGCCGGTGTCGGCCCCGAGATCATCATGA AGGCGCTCACACACCGCGCGGTGTACGAGCAATGCCGACCTCTGGTGATTGGCGACACGGCACGACTGCGCGATGCCGCC CAACGTACCGGCGCGGCACTGGAAGTTCGCTCGATCGAGCGCCCTGCCGACGCCGCCTTCCGCTACGGCGTAGTGGACTG CATCGACCTCGGCCTCATTCCTGCCGACCTGCCCTACGGCAAGCTCTCTCCCATCGCGGGCGATGCCGCGTATCAGTACA TCGCCCGCACCGTCGAGCTGACGTCCGCTGGCGAACTGGATGCCATCTGTACCGCGCCGCTGAACAAGGAAGCGCTGCAC GCCGGCGGCCACATCTTCCCGGGCCACACCGAAATGCTGGCGCACCTGACCGGCATCGATGAGGTTTCGATGATGCTCGT GGCGCCCAACCTGCGCGTGATCCACGTGACGACCCATATCGGGCTGCTAGACGCCATCCGCCGCATCGAGCCGGGCCTGG TCCAGCGCACCATCGAACGCGCGCACGCCACGCTGGTACGCGCCGGCATCGAGAACCCGCGCATCGGTGTCTGCGGCATC AACCCGCATGCGGGAGAAAACGGGCTGTTCGGCCATGGCGAAGAAGAGCAAAAGATCATCCCCGCCGTGCAGGTGCTGCA GGCACGCGGCTGGCGCGTAGAGGGCCCGCTGCCCGCCGACACGCTGTTCTTCCGCGCCGGCCGTGGCGACTTCGATGTGG TGGTGGCGATGTATCACGACCAGGGCCACGGACCGGTCAAGGTGATGGGCCTGGAAGCCGGTGTGAACGTCACCGTGGGC CTGCCGGTAATCCGTACTTCGGTCGACCATGGAACCGCGTTCGACATTGCCGGCAAGGGCATCGCCGATGAACGCAGCAT GCTCGAAGCGTTTCGCCAGGCCTGTGAACTCGCCACCCGACACGATGACCCGCAAGCCGTACGTGCGGCCTGA
Upstream 100 bases:
>100_bases TGCTGGCCGAGGCCGCGTCGAAGGTCAAGCGTCTGCTGGGCAACAACCCCAAGCCGCTGAGCCACGCAGACATCAAGGCT ATCTACCAGCGCCTGCTGCC
Downstream 100 bases:
>100_bases CATCCCATCCACGCAGCACGAATTGATGTAGCGCCCCCGCGCAAGGCCCGACCCGACGGAGACACGCCGGGCTGGCCGGA GCCATTCGCTCAAGAATCAG
Product: 4-hydroxythreonine-4-phosphate dehydrogenase
Products: NA
Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]
Number of amino acids: Translated: 770; Mature: 770
Protein sequence:
>770_residues MNTSAHTAPKLLILADDLSGAADCAVAGVRAGLRSAVMLRADVGHPIGYPTSADVLALDTDTRRANAVDAAATQVAAWHA LARPATRLYKKIDSTLRGNVAAEVAALAPLAGLAIVAPAFPAAGRTTRDGRQWLHGVAVEDTEVWRNESIGGRADLRVML ERQGLQTAVLTLDDIRAGAAALAGRLAALQADGVQAVVCDAQTDDDLAHIAETSVRLAHVFWVGSAGLAPALIRAAGLGS ANAAVEGDAATAIAGPVLTVVGSMSSVSHAQASELKAAAGARLLSLELPVEELDTPQADITQTVIDALCEGRDVLVTLSQ TTRGNSADGLHFCRRLATLLAPALPHAGGLIATGGETARAVLSTAGIDALRLCDEIESGMPLLHAQLTGVGGVLPVVTKA GGFGTPGSLHAAWRRLIETAASTPPKGTHAMTYRPVIGITMGDAAGVGPEIIMKALTHRAVYEQCRPLVIGDTARLRDAA QRTGAALEVRSIERPADAAFRYGVVDCIDLGLIPADLPYGKLSPIAGDAAYQYIARTVELTSAGELDAICTAPLNKEALH AGGHIFPGHTEMLAHLTGIDEVSMMLVAPNLRVIHVTTHIGLLDAIRRIEPGLVQRTIERAHATLVRAGIENPRIGVCGI NPHAGENGLFGHGEEEQKIIPAVQVLQARGWRVEGPLPADTLFFRAGRGDFDVVVAMYHDQGHGPVKVMGLEAGVNVTVG LPVIRTSVDHGTAFDIAGKGIADERSMLEAFRQACELATRHDDPQAVRAA
Sequences:
>Translated_770_residues MNTSAHTAPKLLILADDLSGAADCAVAGVRAGLRSAVMLRADVGHPIGYPTSADVLALDTDTRRANAVDAAATQVAAWHA LARPATRLYKKIDSTLRGNVAAEVAALAPLAGLAIVAPAFPAAGRTTRDGRQWLHGVAVEDTEVWRNESIGGRADLRVML ERQGLQTAVLTLDDIRAGAAALAGRLAALQADGVQAVVCDAQTDDDLAHIAETSVRLAHVFWVGSAGLAPALIRAAGLGS ANAAVEGDAATAIAGPVLTVVGSMSSVSHAQASELKAAAGARLLSLELPVEELDTPQADITQTVIDALCEGRDVLVTLSQ TTRGNSADGLHFCRRLATLLAPALPHAGGLIATGGETARAVLSTAGIDALRLCDEIESGMPLLHAQLTGVGGVLPVVTKA GGFGTPGSLHAAWRRLIETAASTPPKGTHAMTYRPVIGITMGDAAGVGPEIIMKALTHRAVYEQCRPLVIGDTARLRDAA QRTGAALEVRSIERPADAAFRYGVVDCIDLGLIPADLPYGKLSPIAGDAAYQYIARTVELTSAGELDAICTAPLNKEALH AGGHIFPGHTEMLAHLTGIDEVSMMLVAPNLRVIHVTTHIGLLDAIRRIEPGLVQRTIERAHATLVRAGIENPRIGVCGI NPHAGENGLFGHGEEEQKIIPAVQVLQARGWRVEGPLPADTLFFRAGRGDFDVVVAMYHDQGHGPVKVMGLEAGVNVTVG LPVIRTSVDHGTAFDIAGKGIADERSMLEAFRQACELATRHDDPQAVRAA >Mature_770_residues MNTSAHTAPKLLILADDLSGAADCAVAGVRAGLRSAVMLRADVGHPIGYPTSADVLALDTDTRRANAVDAAATQVAAWHA LARPATRLYKKIDSTLRGNVAAEVAALAPLAGLAIVAPAFPAAGRTTRDGRQWLHGVAVEDTEVWRNESIGGRADLRVML ERQGLQTAVLTLDDIRAGAAALAGRLAALQADGVQAVVCDAQTDDDLAHIAETSVRLAHVFWVGSAGLAPALIRAAGLGS ANAAVEGDAATAIAGPVLTVVGSMSSVSHAQASELKAAAGARLLSLELPVEELDTPQADITQTVIDALCEGRDVLVTLSQ TTRGNSADGLHFCRRLATLLAPALPHAGGLIATGGETARAVLSTAGIDALRLCDEIESGMPLLHAQLTGVGGVLPVVTKA GGFGTPGSLHAAWRRLIETAASTPPKGTHAMTYRPVIGITMGDAAGVGPEIIMKALTHRAVYEQCRPLVIGDTARLRDAA QRTGAALEVRSIERPADAAFRYGVVDCIDLGLIPADLPYGKLSPIAGDAAYQYIARTVELTSAGELDAICTAPLNKEALH AGGHIFPGHTEMLAHLTGIDEVSMMLVAPNLRVIHVTTHIGLLDAIRRIEPGLVQRTIERAHATLVRAGIENPRIGVCGI NPHAGENGLFGHGEEEQKIIPAVQVLQARGWRVEGPLPADTLFFRAGRGDFDVVVAMYHDQGHGPVKVMGLEAGVNVTVG LPVIRTSVDHGTAFDIAGKGIADERSMLEAFRQACELATRHDDPQAVRAA
Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]
COG id: COG1995
COG function: function code H; Pyridoxal phosphate biosynthesis protein
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the pdxA family [H]
Homologues:
Organism=Escherichia coli, GI1786237, Length=322, Percent_Identity=38.8198757763975, Blast_Score=184, Evalue=2e-47,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005255 [H]
Pfam domain/function: PF04166 PdxA [H]
EC number: =1.1.1.262 [H]
Molecular weight: Translated: 80137; Mature: 80137
Theoretical pI: Translated: 6.19; Mature: 6.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTSAHTAPKLLILADDLSGAADCAVAGVRAGLRSAVMLRADVGHPIGYPTSADVLALDT CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEC DTRRANAVDAAATQVAAWHALARPATRLYKKIDSTLRGNVAAEVAALAPLAGLAIVAPAF CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC PAAGRTTRDGRQWLHGVAVEDTEVWRNESIGGRADLRVMLERQGLQTAVLTLDDIRAGAA CCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHEEHHCCCCEEEEEHHHHHHHHH ALAGRLAALQADGVQAVVCDAQTDDDLAHIAETSVRLAHVFWVGSAGLAPALIRAAGLGS HHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHCCCC ANAAVEGDAATAIAGPVLTVVGSMSSVSHAQASELKAAAGARLLSLELPVEELDTPQADI CCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCHHHH TQTVIDALCEGRDVLVTLSQTTRGNSADGLHFCRRLATLLAPALPHAGGLIATGGETARA HHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH VLSTAGIDALRLCDEIESGMPLLHAQLTGVGGVLPVVTKAGGFGTPGSLHAAWRRLIETA HHHHCCHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHH ASTPPKGTHAMTYRPVIGITMGDAAGVGPEIIMKALTHRAVYEQCRPLVIGDTARLRDAA CCCCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH QRTGAALEVRSIERPADAAFRYGVVDCIDLGLIPADLPYGKLSPIAGDAAYQYIARTVEL HHCCCEEEECCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC TSAGELDAICTAPLNKEALHAGGHIFPGHTEMLAHLTGIDEVSMMLVAPNLRVIHVTTHI CCCCCCCEEECCCCCHHHHHCCCCCCCCHHHHHHHHCCCCHHEEEEECCCEEEEEEEHHH GLLDAIRRIEPGLVQRTIERAHATLVRAGIENPRIGVCGINPHAGENGLFGHGEEEQKII HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH PAVQVLQARGWRVEGPLPADTLFFRAGRGDFDVVVAMYHDQGHGPVKVMGLEAGVNVTVG HHHHHHHHCCCEECCCCCHHHEEEECCCCCEEEEEEEEECCCCCCEEEEEEECCCEEEEC LPVIRTSVDHGTAFDIAGKGIADERSMLEAFRQACELATRHDDPQAVRAA CCEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCC >Mature Secondary Structure MNTSAHTAPKLLILADDLSGAADCAVAGVRAGLRSAVMLRADVGHPIGYPTSADVLALDT CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEC DTRRANAVDAAATQVAAWHALARPATRLYKKIDSTLRGNVAAEVAALAPLAGLAIVAPAF CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC PAAGRTTRDGRQWLHGVAVEDTEVWRNESIGGRADLRVMLERQGLQTAVLTLDDIRAGAA CCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHEEHHCCCCEEEEEHHHHHHHHH ALAGRLAALQADGVQAVVCDAQTDDDLAHIAETSVRLAHVFWVGSAGLAPALIRAAGLGS HHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHCCCC ANAAVEGDAATAIAGPVLTVVGSMSSVSHAQASELKAAAGARLLSLELPVEELDTPQADI CCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCHHHH TQTVIDALCEGRDVLVTLSQTTRGNSADGLHFCRRLATLLAPALPHAGGLIATGGETARA HHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH VLSTAGIDALRLCDEIESGMPLLHAQLTGVGGVLPVVTKAGGFGTPGSLHAAWRRLIETA HHHHCCHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHH ASTPPKGTHAMTYRPVIGITMGDAAGVGPEIIMKALTHRAVYEQCRPLVIGDTARLRDAA CCCCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH QRTGAALEVRSIERPADAAFRYGVVDCIDLGLIPADLPYGKLSPIAGDAAYQYIARTVEL HHCCCEEEECCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC TSAGELDAICTAPLNKEALHAGGHIFPGHTEMLAHLTGIDEVSMMLVAPNLRVIHVTTHI CCCCCCCEEECCCCCHHHHHCCCCCCCCHHHHHHHHCCCCHHEEEEECCCEEEEEEEHHH GLLDAIRRIEPGLVQRTIERAHATLVRAGIENPRIGVCGINPHAGENGLFGHGEEEQKII HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH PAVQVLQARGWRVEGPLPADTLFFRAGRGDFDVVVAMYHDQGHGPVKVMGLEAGVNVTVG HHHHHHHHCCCEECCCCCHHHEEEECCCCCEEEEEEEEECCCCCCEEEEEEECCCEEEEC LPVIRTSVDHGTAFDIAGKGIADERSMLEAFRQACELATRHDDPQAVRAA CCEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12235376 [H]