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The map label for this gene is yiaY [H]

Identifier: 187927662

GI number: 187927662

Start: 600353

End: 601522

Strand: Reverse

Name: yiaY [H]

Synonym: Rpic_0565

Alternate gene names: 187927662

Gene position: 601522-600353 (Counterclockwise)

Preceding gene: 187927663

Following gene: 187927661

Centisome position: 15.26

GC content: 63.25

Gene sequence:

>1170_bases
ATGTCCTCCACCTACCATTTCCAGACCGTCAAGCACATCGTCCACGGCGCAGGCAGTCTGGCATTGCTGCCCGAAAAGCT
CGCGCTGCTTGATGTGCCCGTCAAACGCATCGCACTCATCACCCAACCGGTGATGGAGCAGAACGGCGTGATCGGCCGCG
TGGTGCAAGCGCTGGCCGCGCGCGACATCGAGGCGCGCATCGTACGCGGCGTCGAACCGGAACCGACGATTGAGAACGTC
GAGACCGTCTTCCGCGAGCAGATCGCGCCGTTTGCGCCGGATGCCATCCTGTCAATCGGTGGCGGCAGCGTGCTGGATGC
GGCCAAGCTGTTTGCAGTGCGCCTGACCAACGAACAGCCGCTGCGCGAATGGCTCGGCATTGATCTGATCAAGCGCCCCG
GCATTCCGCTGGTGTTGGTCCCAACCACGGCGGGCACGGGTTCTGAAGTCACGCCCAACGCCATCGTCACGCTGCCCGAT
GAAGAACTGAAGGTGGGCATCGTCAGCCGACATCTGCTGCCACAACTGGTGATTCTCGATGCGGAACTGACCTTCGACCT
GCCCAAACCGATCACGGCAGCCACGGGCATCGACGCATTCGTGCATTCGCTGGAGTCGTATATCTCGACCAAGGCCAACC
CGGTGAGCGACATGTTTGCGATGGAGTCGATGCGGCTCATCGGCGCGAACCTTGTCGAGGCATATCAGAACGGCCGCTCG
GTCAAGGCGCGCGAGGCGATGATGCTGGGTTCGATGTACGGCGGCCTGGCGCTGACCGCCGCCGGCACGGCCGCCGTGCA
TGCGCTGGCGTATCCGCTCGGTGGCATGTTCGGCATTACGCACGGTGTGGCCAACGCGATGCTGTTGCCGCACGTAATGT
CGTTCAACAAGGATGCCATCGTCGGGCGGCTGGCCAACGTGGCACGTGCACTGGACATCAGCAGCCATGACAGTGACGAC
GAGACCGCCGCCGATGCGCTCATCGAACGGCTGACCGAGTGGACCGACGTTGTGCAGATTCCGCAGGACTTGCGCCAGTT
CGGCGTGTCGGAAACGCACCTGGACGTGCTGGCCGAGGCCGCGTCGAAGGTCAAGCGTCTGCTGGGCAACAACCCCAAGC
CGCTGAGCCACGCAGACATCAAGGCTATCTACCAGCGCCTGCTGCCGTGA

Upstream 100 bases:

>100_bases
TGAGAAAAGCCGCGAACGCCTGGCTGAAGCGCTCGCCATCTACCGTGCCGCGCTGAACGTCGCCTAAGCACTGCCGCCCG
CCCCAACATCATCGATCGCC

Downstream 100 bases:

>100_bases
ACACGTCCGCCCACACCGCTCCGAAGCTGCTGATCCTGGCCGACGACCTGTCGGGCGCCGCCGATTGCGCGGTGGCCGGC
GTGCGGGCCGGATTGCGCAG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSSTYHFQTVKHIVHGAGSLALLPEKLALLDVPVKRIALITQPVMEQNGVIGRVVQALAARDIEARIVRGVEPEPTIENV
ETVFREQIAPFAPDAILSIGGGSVLDAAKLFAVRLTNEQPLREWLGIDLIKRPGIPLVLVPTTAGTGSEVTPNAIVTLPD
EELKVGIVSRHLLPQLVILDAELTFDLPKPITAATGIDAFVHSLESYISTKANPVSDMFAMESMRLIGANLVEAYQNGRS
VKAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFGITHGVANAMLLPHVMSFNKDAIVGRLANVARALDISSHDSDD
ETAADALIERLTEWTDVVQIPQDLRQFGVSETHLDVLAEAASKVKRLLGNNPKPLSHADIKAIYQRLLP

Sequences:

>Translated_389_residues
MSSTYHFQTVKHIVHGAGSLALLPEKLALLDVPVKRIALITQPVMEQNGVIGRVVQALAARDIEARIVRGVEPEPTIENV
ETVFREQIAPFAPDAILSIGGGSVLDAAKLFAVRLTNEQPLREWLGIDLIKRPGIPLVLVPTTAGTGSEVTPNAIVTLPD
EELKVGIVSRHLLPQLVILDAELTFDLPKPITAATGIDAFVHSLESYISTKANPVSDMFAMESMRLIGANLVEAYQNGRS
VKAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFGITHGVANAMLLPHVMSFNKDAIVGRLANVARALDISSHDSDD
ETAADALIERLTEWTDVVQIPQDLRQFGVSETHLDVLAEAASKVKRLLGNNPKPLSHADIKAIYQRLLP
>Mature_388_residues
SSTYHFQTVKHIVHGAGSLALLPEKLALLDVPVKRIALITQPVMEQNGVIGRVVQALAARDIEARIVRGVEPEPTIENVE
TVFREQIAPFAPDAILSIGGGSVLDAAKLFAVRLTNEQPLREWLGIDLIKRPGIPLVLVPTTAGTGSEVTPNAIVTLPDE
ELKVGIVSRHLLPQLVILDAELTFDLPKPITAATGIDAFVHSLESYISTKANPVSDMFAMESMRLIGANLVEAYQNGRSV
KAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFGITHGVANAMLLPHVMSFNKDAIVGRLANVARALDISSHDSDDE
TAADALIERLTEWTDVVQIPQDLRQFGVSETHLDVLAEAASKVKRLLGNNPKPLSHADIKAIYQRLLP

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=330, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI48994951, Length=385, Percent_Identity=36.3636363636364, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1789163, Length=356, Percent_Identity=31.7415730337079, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082107, Length=351, Percent_Identity=33.6182336182336, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787493, Length=374, Percent_Identity=31.8181818181818, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789386, Length=368, Percent_Identity=27.1739130434783, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=399, Percent_Identity=27.3182957393484, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321181, Length=332, Percent_Identity=34.9397590361446, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24657991, Length=404, Percent_Identity=25.7425742574257, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41745; Mature: 41614

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTYHFQTVKHIVHGAGSLALLPEKLALLDVPVKRIALITQPVMEQNGVIGRVVQALAA
CCCCHHHHHHHHHHHCCCCCEECHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDIEARIVRGVEPEPTIENVETVFREQIAPFAPDAILSIGGGSVLDAAKLFAVRLTNEQP
CCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHEECCCCHHHHHHHHHHEEECCCHH
LREWLGIDLIKRPGIPLVLVPTTAGTGSEVTPNAIVTLPDEELKVGIVSRHLLPQLVILD
HHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHEEEEE
AELTFDLPKPITAATGIDAFVHSLESYISTKANPVSDMFAMESMRLIGANLVEAYQNGRS
CHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VKAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFGITHGVANAMLLPHVMSFNKDAI
CHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGRLANVARALDISSHDSDDETAADALIERLTEWTDVVQIPQDLRQFGVSETHLDVLAEA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASKVKRLLGNNPKPLSHADIKAIYQRLLP
HHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSTYHFQTVKHIVHGAGSLALLPEKLALLDVPVKRIALITQPVMEQNGVIGRVVQALAA
CCCHHHHHHHHHHHCCCCCEECHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDIEARIVRGVEPEPTIENVETVFREQIAPFAPDAILSIGGGSVLDAAKLFAVRLTNEQP
CCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHEECCCCHHHHHHHHHHEEECCCHH
LREWLGIDLIKRPGIPLVLVPTTAGTGSEVTPNAIVTLPDEELKVGIVSRHLLPQLVILD
HHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHEEEEE
AELTFDLPKPITAATGIDAFVHSLESYISTKANPVSDMFAMESMRLIGANLVEAYQNGRS
CHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VKAREAMMLGSMYGGLALTAAGTAAVHALAYPLGGMFGITHGVANAMLLPHVMSFNKDAI
CHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGRLANVARALDISSHDSDDETAADALIERLTEWTDVVQIPQDLRQFGVSETHLDVLAEA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASKVKRLLGNNPKPLSHADIKAIYQRLLP
HHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]