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The map label for this gene is ycgO [H]

Identifier: 187927660

GI number: 187927660

Start: 596503

End: 597933

Strand: Reverse

Name: ycgO [H]

Synonym: Rpic_0563

Alternate gene names: 187927660

Gene position: 597933-596503 (Counterclockwise)

Preceding gene: 187927661

Following gene: 187927659

Centisome position: 15.17

GC content: 62.33

Gene sequence:

>1431_bases
ATGACCTCGTTTTCGACCTGGGACACCACCATGATCATCGCCATGGTCGTGGTCTATATCGTGGTGACCAGCGTGGCCAG
CATCCGGCTGCGCAGCCGCACTTCCGAGCAATTCATGGTGGCCGGTCGCTCGATGCCGGCCGTGGTGGTGGCCGTGCTGC
TGATGTCGGAATACATCGGCGCCAAGTCGACCATCGGCACCTCGCAAGAAGCCTTCAGCGTGGGTATTGCAGCGTCGTGG
TCGGTCATCTCTGCCGCCATCGGCTTTCTGCTGTTTGGCCTGTTCATGGCCAAGCGTCTGTATGCGTCGGGGCAGTTCAC
CATCTCCGGCTTCATCGCCAAGAAGTACGGCAACACGGCCAAGCTGGTCGTGTCGGCCGTCATGATCTACGCGCTGTTTC
TGGTGAACGTGGGCAACTATGTCAGCGGCGCGGCAGCCATCTCCACGGTCATGCACATCGACCTTCCGATCGCGGCGCTC
ATCACGGCTGCCGTCAGCACGATCTACTTCGTGTGGGGCGGTCTCAAGAGCGTGGCGTATCTGACCATCGTGCACAGCGC
GGTCAAGGTGGTCGGCATCGGCATCATCGTCGCGGTGGCGTGGAAGCTCTCTGGCGGCATTGCCCCGATGGCGCAGGCCA
TGCCGGAGCACTACTTCACGTGGAAGGGTGCGCTGTCCGGCGGCACCATCGGCGCGTGGATCATCGGTTCGGCCGGGGCG
ATCTTCTCCACCCAGTTCATCATTCAAGCCATTTCTTCCACCAAGAGCCCTGAAGCCGCCCGCTCGGCTTCGCTCATGGC
GGCGGTGCTGTGCGTGCCGATCTCGATTGCGCTGGGCTTCATCGGCGTGGCCGCCAAGTATCTGTACCCGGGCATCAAGA
GCCTGTATGCGCTGCCGGTCTTTCTGCAACACATGCATCCGCTGCTGGCCGGCGTGGTAACGACTTCGCTGGTGGCGTCG
ATCTTCGTGAGCGTGTGTACGGTGGCACTCGCCATTGCTTCGCTCATCGTGACCGACTTCTATGTGCCGCGCTATCGCCC
GTCGGCCGAGCAGGAAATGCGCATGACACGCTGGATCTCGCTGGCGGTGGGCGTGCTGCCGCTGGTGTTCGTGCTGTTCG
TGCCGCAAATCCTGGCGCTATCGTTCTTCACGCGGGCGCTGCGGCTGTCGGTGTCCATCGTTGCGCTCATCGGCATCTAT
CTGCCGTTCTTCAACAGCAGTCGTGGAGCCGTTTCGGGCCTGATCCTGGCCGCGATTGCAACCACCATCTGGTATCTGCT
CGGCAACCCGTTCGGCGTCGACAACATGTACATCGCGCTCGTCACGCCCGCCCTCGTTCTGGTGGTCGAGAAGCTGCTCT
TTCGCGCGGCTGAGCCTGCACAGGCCAGCGCACCCGTCGCCAACATCAAGCCAAACAACGCGGCGCATTGA

Upstream 100 bases:

>100_bases
ACGCAGCACGAATTGATGTAGCGCCCCCGCGCAAGGCCCGACCCGACGGAGACACGCCGGGCTGGCCGGAGCCATTCGCT
CAAGAATCAGGAGACAAAAG

Downstream 100 bases:

>100_bases
TCCCCAGACACCGAGCATTGAACTGAGACATAACATGACTGCCACCCTTCCGTCCTACGCCGCCTTCGATTCGAACGTGC
GAGCTGCCTATACCGACGCC

Product: Na+/solute symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTSFSTWDTTMIIAMVVVYIVVTSVASIRLRSRTSEQFMVAGRSMPAVVVAVLLMSEYIGAKSTIGTSQEAFSVGIAASW
SVISAAIGFLLFGLFMAKRLYASGQFTISGFIAKKYGNTAKLVVSAVMIYALFLVNVGNYVSGAAAISTVMHIDLPIAAL
ITAAVSTIYFVWGGLKSVAYLTIVHSAVKVVGIGIIVAVAWKLSGGIAPMAQAMPEHYFTWKGALSGGTIGAWIIGSAGA
IFSTQFIIQAISSTKSPEAARSASLMAAVLCVPISIALGFIGVAAKYLYPGIKSLYALPVFLQHMHPLLAGVVTTSLVAS
IFVSVCTVALAIASLIVTDFYVPRYRPSAEQEMRMTRWISLAVGVLPLVFVLFVPQILALSFFTRALRLSVSIVALIGIY
LPFFNSSRGAVSGLILAAIATTIWYLLGNPFGVDNMYIALVTPALVLVVEKLLFRAAEPAQASAPVANIKPNNAAH

Sequences:

>Translated_476_residues
MTSFSTWDTTMIIAMVVVYIVVTSVASIRLRSRTSEQFMVAGRSMPAVVVAVLLMSEYIGAKSTIGTSQEAFSVGIAASW
SVISAAIGFLLFGLFMAKRLYASGQFTISGFIAKKYGNTAKLVVSAVMIYALFLVNVGNYVSGAAAISTVMHIDLPIAAL
ITAAVSTIYFVWGGLKSVAYLTIVHSAVKVVGIGIIVAVAWKLSGGIAPMAQAMPEHYFTWKGALSGGTIGAWIIGSAGA
IFSTQFIIQAISSTKSPEAARSASLMAAVLCVPISIALGFIGVAAKYLYPGIKSLYALPVFLQHMHPLLAGVVTTSLVAS
IFVSVCTVALAIASLIVTDFYVPRYRPSAEQEMRMTRWISLAVGVLPLVFVLFVPQILALSFFTRALRLSVSIVALIGIY
LPFFNSSRGAVSGLILAAIATTIWYLLGNPFGVDNMYIALVTPALVLVVEKLLFRAAEPAQASAPVANIKPNNAAH
>Mature_475_residues
TSFSTWDTTMIIAMVVVYIVVTSVASIRLRSRTSEQFMVAGRSMPAVVVAVLLMSEYIGAKSTIGTSQEAFSVGIAASWS
VISAAIGFLLFGLFMAKRLYASGQFTISGFIAKKYGNTAKLVVSAVMIYALFLVNVGNYVSGAAAISTVMHIDLPIAALI
TAAVSTIYFVWGGLKSVAYLTIVHSAVKVVGIGIIVAVAWKLSGGIAPMAQAMPEHYFTWKGALSGGTIGAWIIGSAGAI
FSTQFIIQAISSTKSPEAARSASLMAAVLCVPISIALGFIGVAAKYLYPGIKSLYALPVFLQHMHPLLAGVVTTSLVASI
FVSVCTVALAIASLIVTDFYVPRYRPSAEQEMRMTRWISLAVGVLPLVFVLFVPQILALSFFTRALRLSVSIVALIGIYL
PFFNSSRGAVSGLILAAIATTIWYLLGNPFGVDNMYIALVTPALVLVVEKLLFRAAEPAQASAPVANIKPNNAAH

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17539284, Length=456, Percent_Identity=22.3684210526316, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50346; Mature: 50214

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSFSTWDTTMIIAMVVVYIVVTSVASIRLRSRTSEQFMVAGRSMPAVVVAVLLMSEYIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHC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HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]