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The map label for this gene is 187927601

Identifier: 187927601

GI number: 187927601

Start: 534186

End: 536777

Strand: Reverse

Name: 187927601

Synonym: Rpic_0501

Alternate gene names: NA

Gene position: 536777-534186 (Counterclockwise)

Preceding gene: 187927602

Following gene: 187927600

Centisome position: 13.61

GC content: 66.28

Gene sequence:

>2592_bases
GTGCCACGCCATCTCGCCGACTACCGCAGCAAGCGCGATTTCACGCAGACCCAGGAACCCGCCGGCGCGCGCCGCAAAGC
CGACGAGCAGCGTGACCATGGCGCCCTGCACTTCGTGATCCAGAAGCACGACGCAACGCGACTGCACTACGACTTCCGGC
TGGAACTCGACGGCACGCTCAAGAGCTGGGCCGTCCCCAAGGGCCCGAGCCTGGACCCCGCCGACAAGCGCCTCGCGGTA
CATGTTGAAGACCACCCGCTGGACTACGCGGATTTCGAAGGCCATATCCCCGAAGGACAATACGGCGGCGGCGACGTGAT
CGTGTGGGACCGCGGGACATGGCGCCCGCATGGCGATCCGCGCAAGGCCTATCGCGACGGCAAGCTCAAATTCGACCTCC
ATGGCGAGAAGCTGCATGGTGCATGGGCGCTGGTACGCACGCATTTGCACGGCACGGGCAGACATCCGAAAGAACAGTGG
CTGCTGATCAAGGAACGCGACGACCAGGTGCGCGCATCGAGCGACTACGACGTGACACAGGCGCTGCCCGCCAGCGTGAT
CACCGGAGAGAACGTCGGCGCAAAACCGAAGGCTAAGGCCGATGGCCGCAAGACCCAGCGTGCCGATCCGGCACAAGTCC
AGCCGCCCGCCGGTGCCGTGCCCGGCACGTTGCCGAAAACGCTGGAGCCGCAGCTTGCCACGCTCGTCGATGCGCCGCCA
AGGCAAGGCGAGTGGAATTACGAAGTGAAGTTCGACGGCTACCGCATCCTGGCGCGCATCGACGGCAACACCGTGCGCCT
GTTCAGCCGCAACGGCCGCGACTGGACGGCCAAGCTGCCGCGTCAGGCGCGCACGCTGCAGGCGCTGGGCCTGCGCGAGG
CGTGGCTCGACGGCGAAGTCGTGGTGATGGGCGAGCGCGGCGTGCCCGACTTCCAGGCGCTGCAGAACGCCTTCGAAACC
GCGCATGCCGAACACATTGCCTACTACCTGTTCGACATCCCGTTCTGCAACGGCATGGACTTGCGCGGTGTGCCGTTGCG
CGAGCGGCGGGCGCTGCTTGAGCGCATTCTCGATGCCGCCCCGGGCAACCTGGACCGCGAAGCGGTGCTCTTCTCAGGGA
CATTTCACGCGGCACCCGAAGACTTGCTGTCTTCCGCGTGCAGCATGTCGCTCGAAGGGGTGATCGGCAAGCGCGCCGAT
GCGCCGTACCGGGCCGGCCGCAGCCCTGCCTGGATCAAGCTCAAATGCGGGCAGCGGCAGGAATTCGTGATCGGCGGGTA
CAGTGCGCCCAAGGGTAGCCGCAGCGGCTTCGGTGCCCTGCTGCTCGGCGTGTATGACGACGCGGGCAAGCTGCGCTATG
CGGGCCGTGTCGGCACGGGCTTCAACGAGACGAGTCTGCACGCTTTGCACCACGAGCTGACGGGTCTGACCGTCGACACG
CCGCCCTTCGCCAACCCGCCCACCGGCAGCGATGCGCGCGACGTGCAATGGGTGAAGCCCGAACGCGTGGCGGAAATCGC
CTTTGCCGAATGGACGCGCGAAGGCATCGTGCGGCAAGCCGTGTTCCAAGGTTTGCGTGACGACAAACTCGCGCGCAACA
TCGTGCGTGAACAAGCCAAGCCGCCCAGCGCTGCCGCACGCAAGGAGACCCGCGCCGTGAATGCTGCCGAACGCAAGGTG
CGCCCCGGTGCCGAACGCATCGCCGATGTGGACGTCACGCATCCAGATCGCGTGATCGAGAAAGCCAGTGGCACCACCAA
GGCGGACCTGGCGCGCTATTACGCCGGTGTGGCCGAATGGATGCTGCCGCATCTTCGCAACCGCCCGACATCGCTCGTAC
GCGCGCCCGACGGCATCGACGGCGAGCGCTTCTTCCAGAAGCATTCCGCCGCGCTCAAGCTGCAGGGCATCACGCAGCTG
GACCCATCGCTCGACCCGGGGCATCCGTCGCTGCTTGCGATCAACTCGGCCGAGGCCCTGGTCGGCGCGGTGCAGATGGG
CACGGTGGAGTTCCACACGTGGAATGCGCTGGCCGACCGCATCGAACAACCCGACCGCATCGTCTTCGATATCGACCCGG
ACCCGGCGCTGCCTTTCGCGCGCGTGATCGAGGCCACGCAGCTCATGCTGGCCATGCTTGATGAACTCGGCCTGAAGGCC
TTCCTGAAAACCAGCGGTGGGCATGGCATGCACGTGGTGGTGCTGCTCACGCGCCGCGAAGCCGCTGGCTGGGACACGCT
CAAAACGTTCGCGCAAGCCGTGGTGCAACACATGGCCGCGACCTTCCCTGACCGCTTTGTCGCCAAGATGGGGCCGCAGA
ACCGCGTGGGAAAAATCTTCATCGACTATCTGCGCAACAACCGCGGTGCGAGCACGGTGGCCGCCTATTCGGTGCGCGCG
CGGACGGGGTTGCCAGTGTCCGTGCCGATCCGCCATGACGAGCTGGAAGGGCTGCAGTCGTCTGCCCAGTGGACGCTGCG
CACGCTGCCCGAACGGCTCGCCAAGCTCAAGGGCGATCCTTGGGCCGCCTATGCCGGTACGCGTCAATCGGTCACGGCCG
ACATGCGCAAACGCGTTGGCGCCGATGACTGA

Upstream 100 bases:

>100_bases
AGAGCCTGCCCCGCGCAAGCGGGCACCCCGCAAAGCCGCCTCCAAGACGGCGCGCAAGACCACCACGCGCAAGCGCGCAT
AACACGACGGAGCCGACGCC

Downstream 100 bases:

>100_bases
GCCGTCACACACCGGCGGTTCTCAAAGAATTGGGCGGTGAACGCCCCATTGCTTGTCGGCCGAAGTGCGGGGCCACTGCG
TTAACATGCCTGCGTCTGCA

Product: DNA ligase D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 863; Mature: 862

Protein sequence:

>863_residues
MPRHLADYRSKRDFTQTQEPAGARRKADEQRDHGALHFVIQKHDATRLHYDFRLELDGTLKSWAVPKGPSLDPADKRLAV
HVEDHPLDYADFEGHIPEGQYGGGDVIVWDRGTWRPHGDPRKAYRDGKLKFDLHGEKLHGAWALVRTHLHGTGRHPKEQW
LLIKERDDQVRASSDYDVTQALPASVITGENVGAKPKAKADGRKTQRADPAQVQPPAGAVPGTLPKTLEPQLATLVDAPP
RQGEWNYEVKFDGYRILARIDGNTVRLFSRNGRDWTAKLPRQARTLQALGLREAWLDGEVVVMGERGVPDFQALQNAFET
AHAEHIAYYLFDIPFCNGMDLRGVPLRERRALLERILDAAPGNLDREAVLFSGTFHAAPEDLLSSACSMSLEGVIGKRAD
APYRAGRSPAWIKLKCGQRQEFVIGGYSAPKGSRSGFGALLLGVYDDAGKLRYAGRVGTGFNETSLHALHHELTGLTVDT
PPFANPPTGSDARDVQWVKPERVAEIAFAEWTREGIVRQAVFQGLRDDKLARNIVREQAKPPSAAARKETRAVNAAERKV
RPGAERIADVDVTHPDRVIEKASGTTKADLARYYAGVAEWMLPHLRNRPTSLVRAPDGIDGERFFQKHSAALKLQGITQL
DPSLDPGHPSLLAINSAEALVGAVQMGTVEFHTWNALADRIEQPDRIVFDIDPDPALPFARVIEATQLMLAMLDELGLKA
FLKTSGGHGMHVVVLLTRREAAGWDTLKTFAQAVVQHMAATFPDRFVAKMGPQNRVGKIFIDYLRNNRGASTVAAYSVRA
RTGLPVSVPIRHDELEGLQSSAQWTLRTLPERLAKLKGDPWAAYAGTRQSVTADMRKRVGADD

Sequences:

>Translated_863_residues
MPRHLADYRSKRDFTQTQEPAGARRKADEQRDHGALHFVIQKHDATRLHYDFRLELDGTLKSWAVPKGPSLDPADKRLAV
HVEDHPLDYADFEGHIPEGQYGGGDVIVWDRGTWRPHGDPRKAYRDGKLKFDLHGEKLHGAWALVRTHLHGTGRHPKEQW
LLIKERDDQVRASSDYDVTQALPASVITGENVGAKPKAKADGRKTQRADPAQVQPPAGAVPGTLPKTLEPQLATLVDAPP
RQGEWNYEVKFDGYRILARIDGNTVRLFSRNGRDWTAKLPRQARTLQALGLREAWLDGEVVVMGERGVPDFQALQNAFET
AHAEHIAYYLFDIPFCNGMDLRGVPLRERRALLERILDAAPGNLDREAVLFSGTFHAAPEDLLSSACSMSLEGVIGKRAD
APYRAGRSPAWIKLKCGQRQEFVIGGYSAPKGSRSGFGALLLGVYDDAGKLRYAGRVGTGFNETSLHALHHELTGLTVDT
PPFANPPTGSDARDVQWVKPERVAEIAFAEWTREGIVRQAVFQGLRDDKLARNIVREQAKPPSAAARKETRAVNAAERKV
RPGAERIADVDVTHPDRVIEKASGTTKADLARYYAGVAEWMLPHLRNRPTSLVRAPDGIDGERFFQKHSAALKLQGITQL
DPSLDPGHPSLLAINSAEALVGAVQMGTVEFHTWNALADRIEQPDRIVFDIDPDPALPFARVIEATQLMLAMLDELGLKA
FLKTSGGHGMHVVVLLTRREAAGWDTLKTFAQAVVQHMAATFPDRFVAKMGPQNRVGKIFIDYLRNNRGASTVAAYSVRA
RTGLPVSVPIRHDELEGLQSSAQWTLRTLPERLAKLKGDPWAAYAGTRQSVTADMRKRVGADD
>Mature_862_residues
PRHLADYRSKRDFTQTQEPAGARRKADEQRDHGALHFVIQKHDATRLHYDFRLELDGTLKSWAVPKGPSLDPADKRLAVH
VEDHPLDYADFEGHIPEGQYGGGDVIVWDRGTWRPHGDPRKAYRDGKLKFDLHGEKLHGAWALVRTHLHGTGRHPKEQWL
LIKERDDQVRASSDYDVTQALPASVITGENVGAKPKAKADGRKTQRADPAQVQPPAGAVPGTLPKTLEPQLATLVDAPPR
QGEWNYEVKFDGYRILARIDGNTVRLFSRNGRDWTAKLPRQARTLQALGLREAWLDGEVVVMGERGVPDFQALQNAFETA
HAEHIAYYLFDIPFCNGMDLRGVPLRERRALLERILDAAPGNLDREAVLFSGTFHAAPEDLLSSACSMSLEGVIGKRADA
PYRAGRSPAWIKLKCGQRQEFVIGGYSAPKGSRSGFGALLLGVYDDAGKLRYAGRVGTGFNETSLHALHHELTGLTVDTP
PFANPPTGSDARDVQWVKPERVAEIAFAEWTREGIVRQAVFQGLRDDKLARNIVREQAKPPSAAARKETRAVNAAERKVR
PGAERIADVDVTHPDRVIEKASGTTKADLARYYAGVAEWMLPHLRNRPTSLVRAPDGIDGERFFQKHSAALKLQGITQLD
PSLDPGHPSLLAINSAEALVGAVQMGTVEFHTWNALADRIEQPDRIVFDIDPDPALPFARVIEATQLMLAMLDELGLKAF
LKTSGGHGMHVVVLLTRREAAGWDTLKTFAQAVVQHMAATFPDRFVAKMGPQNRVGKIFIDYLRNNRGASTVAAYSVRAR
TGLPVSVPIRHDELEGLQSSAQWTLRTLPERLAKLKGDPWAAYAGTRQSVTADMRKRVGADD

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=330, Percent_Identity=29.3939393939394, Blast_Score=83, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320038, Length=301, Percent_Identity=27.2425249169435, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762424, Length=328, Percent_Identity=27.7439024390244, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 95460; Mature: 95329

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRHLADYRSKRDFTQTQEPAGARRKADEQRDHGALHFVIQKHDATRLHYDFRLELDGTL
CCCHHHHHHHHCCCCCCCCCCCHHHCCHHHCCCCEEEEEEEECCCEEEEEEEEEEECCCH
KSWAVPKGPSLDPADKRLAVHVEDHPLDYADFEGHIPEGQYGGGDVIVWDRGTWRPHGDP
HHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCH
RKAYRDGKLKFDLHGEKLHGAWALVRTHLHGTGRHPKEQWLLIKERDDQVRASSDYDVTQ
HHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCCCCCCCHHH
ALPASVITGENVGAKPKAKADGRKTQRADPAQVQPPAGAVPGTLPKTLEPQLATLVDAPP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
RQGEWNYEVKFDGYRILARIDGNTVRLFSRNGRDWTAKLPRQARTLQALGLREAWLDGEV
CCCCCCEEEEECCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHCCHHHCCCCCE
VVMGERGVPDFQALQNAFETAHAEHIAYYLFDIPFCNGMDLRGVPLRERRALLERILDAA
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
PGNLDREAVLFSGTFHAAPEDLLSSACSMSLEGVIGKRADAPYRAGRSPAWIKLKCGQRQ
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCC
EFVIGGYSAPKGSRSGFGALLLGVYDDAGKLRYAGRVGTGFNETSLHALHHELTGLTVDT
EEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEECC
PPFANPPTGSDARDVQWVKPERVAEIAFAEWTREGIVRQAVFQGLRDDKLARNIVREQAK
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PPSAAARKETRAVNAAERKVRPGAERIADVDVTHPDRVIEKASGTTKADLARYYAGVAEW
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
MLPHLRNRPTSLVRAPDGIDGERFFQKHSAALKLQGITQLDPSLDPGHPSLLAINSAEAL
HHHHHCCCCCCEEECCCCCCHHHHHHHHCCEEEECCCHHCCCCCCCCCCCEEEECCHHHH
VGAVQMGTVEFHTWNALADRIEQPDRIVFDIDPDPALPFARVIEATQLMLAMLDELGLKA
HHHHEECEEEEEHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHE
FLKTSGGHGMHVVVLLTRREAAGWDTLKTFAQAVVQHMAATFPDRFVAKMGPQNRVGKIF
EEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHH
IDYLRNNRGASTVAAYSVRARTGLPVSVPIRHDELEGLQSSAQWTLRTLPERLAKLKGDP
HHHHHCCCCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WAAYAGTRQSVTADMRKRVGADD
CEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRHLADYRSKRDFTQTQEPAGARRKADEQRDHGALHFVIQKHDATRLHYDFRLELDGTL
CCHHHHHHHHCCCCCCCCCCCHHHCCHHHCCCCEEEEEEEECCCEEEEEEEEEEECCCH
KSWAVPKGPSLDPADKRLAVHVEDHPLDYADFEGHIPEGQYGGGDVIVWDRGTWRPHGDP
HHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCH
RKAYRDGKLKFDLHGEKLHGAWALVRTHLHGTGRHPKEQWLLIKERDDQVRASSDYDVTQ
HHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCCCCCCCHHH
ALPASVITGENVGAKPKAKADGRKTQRADPAQVQPPAGAVPGTLPKTLEPQLATLVDAPP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
RQGEWNYEVKFDGYRILARIDGNTVRLFSRNGRDWTAKLPRQARTLQALGLREAWLDGEV
CCCCCCEEEEECCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHCCHHHCCCCCE
VVMGERGVPDFQALQNAFETAHAEHIAYYLFDIPFCNGMDLRGVPLRERRALLERILDAA
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
PGNLDREAVLFSGTFHAAPEDLLSSACSMSLEGVIGKRADAPYRAGRSPAWIKLKCGQRQ
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCC
EFVIGGYSAPKGSRSGFGALLLGVYDDAGKLRYAGRVGTGFNETSLHALHHELTGLTVDT
EEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEECC
PPFANPPTGSDARDVQWVKPERVAEIAFAEWTREGIVRQAVFQGLRDDKLARNIVREQAK
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PPSAAARKETRAVNAAERKVRPGAERIADVDVTHPDRVIEKASGTTKADLARYYAGVAEW
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
MLPHLRNRPTSLVRAPDGIDGERFFQKHSAALKLQGITQLDPSLDPGHPSLLAINSAEAL
HHHHHCCCCCCEEECCCCCCHHHHHHHHCCEEEECCCHHCCCCCCCCCCCEEEECCHHHH
VGAVQMGTVEFHTWNALADRIEQPDRIVFDIDPDPALPFARVIEATQLMLAMLDELGLKA
HHHHEECEEEEEHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHE
FLKTSGGHGMHVVVLLTRREAAGWDTLKTFAQAVVQHMAATFPDRFVAKMGPQNRVGKIF
EEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHH
IDYLRNNRGASTVAAYSVRARTGLPVSVPIRHDELEGLQSSAQWTLRTLPERLAKLKGDP
HHHHHCCCCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WAAYAGTRQSVTADMRKRVGADD
CEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]