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The map label for this gene is ltrA [H]

Identifier: 187927525

GI number: 187927525

Start: 453659

End: 454576

Strand: Direct

Name: ltrA [H]

Synonym: Rpic_0423

Alternate gene names: 187927525

Gene position: 453659-454576 (Clockwise)

Preceding gene: 187927523

Following gene: 187927526

Centisome position: 11.51

GC content: 64.38

Gene sequence:

>918_bases
ATGGATCTGAACCAATTGGCGTTGTTCGTGCGCGTGGTCGAAGCGGGGAGCTTCACGGCAGCGGCAACGCGGCTCGATTT
GCCTAAATCGTCCGTCAGTCGCGGCATCGCTGCGCTTGAACAGGATTTGAACGTGCGACTGTTACAGCGCACCACGCGCA
CGCTCCATCTGACGGACGCGGGCCAAAGCCTGTATCAGGTGGCGTCGCACGCACTGGAAGACATTGAGCGCGCCACGACC
TGCGCAGGCGAGCTGCAGGACCTGCCGCGCGGCAAGGTCCGGATCACGTCTTCCGAAGACGTCGGCCGTCTGCTGGTAGC
GCCGGTGGCGGCGCGCTTCATGCAGCTGTATCCGGAGATCGATCTGGACGTCGTCCTGACGCCGCGCAATGTCGATCTCG
TGCAGGAAGGTTTCGACCTTGCCGTCCGCGTTGGACGCCTGGCCGATAGTTCGCTGGTGGCGCGGTCGCTTGGCGTGTTG
CGCATCGGCTTGTTCGCGTCGCCCGATTACCTGCAGCGCCGCGGTGCGCCAGACACCGTACAAGGGCTGGCCGACCATTG
CTGCCTCGATTTTCGCGGCACTGGACGCGGCGAAACGCAATGGCGCCTCGTCGGCCCCGATGGGCTGAAAACCGTGGCTG
TGCGTGCGCGCCTGAATGCCGACAGCCTGATTTACCTGGAAACGTTGATTGCTTCAGGCGCCGGTATCGGCCCGCTGCCG
CTGTATGCGAGTGCCGTGGCGCGCGCCAACGCACCGCTGCCGCGACTCGTTCGCGTGCTGCCGGACTATGCGACCAGCGG
TGAGCCGATCAACCTCGTCACACCCTCTGCTCGGTTCGTTCCCAGGCGCGTTCGCTTGCTGATCGACATGCTGACCGAGT
CGATCCGGCAAGAGCTGGAAAACGCCGATCCCACCTGA

Upstream 100 bases:

>100_bases
TTGCCTCGTTTGCACTAGTCGGTTATGGTGGGAAAAAATGTTGCTCTATACGAGACAATAACAATCCGGCTGGCGCGCAT
CACGATAAGAGGAGGAAACC

Downstream 100 bases:

>100_bases
CGTGTCGCCGCAAAGAAGCTGGGCACGTTAAATGTTGTCACGACTGCTCCCGTTGCACGTATCGCACGGCATCATGCGCT
CCACGTGTGCCGGACCAGTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDLNQLALFVRVVEAGSFTAAATRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEDIERATT
CAGELQDLPRGKVRITSSEDVGRLLVAPVAARFMQLYPEIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARSLGVL
RIGLFASPDYLQRRGAPDTVQGLADHCCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLIYLETLIASGAGIGPLP
LYASAVARANAPLPRLVRVLPDYATSGEPINLVTPSARFVPRRVRLLIDMLTESIRQELENADPT

Sequences:

>Translated_305_residues
MDLNQLALFVRVVEAGSFTAAATRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEDIERATT
CAGELQDLPRGKVRITSSEDVGRLLVAPVAARFMQLYPEIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARSLGVL
RIGLFASPDYLQRRGAPDTVQGLADHCCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLIYLETLIASGAGIGPLP
LYASAVARANAPLPRLVRVLPDYATSGEPINLVTPSARFVPRRVRLLIDMLTESIRQELENADPT
>Mature_305_residues
MDLNQLALFVRVVEAGSFTAAATRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEDIERATT
CAGELQDLPRGKVRITSSEDVGRLLVAPVAARFMQLYPEIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARSLGVL
RIGLFASPDYLQRRGAPDTVQGLADHCCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLIYLETLIASGAGIGPLP
LYASAVARANAPLPRLVRVLPDYATSGEPINLVTPSARFVPRRVRLLIDMLTESIRQELENADPT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=35.8108108108108, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=29.9319727891156, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=33.003300330033, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=33.1081081081081, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=31.25, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789440, Length=304, Percent_Identity=29.9342105263158, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=27.7397260273973, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=35.8333333333333, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788706, Length=193, Percent_Identity=28.4974093264249, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788748, Length=136, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=125, Percent_Identity=30.4, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788481, Length=274, Percent_Identity=27.007299270073, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=186, Percent_Identity=26.3440860215054, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788297, Length=149, Percent_Identity=32.2147651006711, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33095; Mature: 33095

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNQLALFVRVVEAGSFTAAATRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDA
CCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEHH
GQSLYQVASHALEDIERATTCAGELQDLPRGKVRITSSEDVGRLLVAPVAARFMQLYPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
DLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARSLGVLRIGLFASPDYLQRRGAPDTV
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCCHHH
QGLADHCCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLIYLETLIASGAGIGPLP
HHHHHHHEECCCCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
LYASAVARANAPLPRLVRVLPDYATSGEPINLVTPSARFVPRRVRLLIDMLTESIRQELE
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
NADPT
CCCCC
>Mature Secondary Structure
MDLNQLALFVRVVEAGSFTAAATRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDA
CCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEHH
GQSLYQVASHALEDIERATTCAGELQDLPRGKVRITSSEDVGRLLVAPVAARFMQLYPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
DLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARSLGVLRIGLFASPDYLQRRGAPDTV
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCCHHH
QGLADHCCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLIYLETLIASGAGIGPLP
HHHHHHHEECCCCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
LYASAVARANAPLPRLVRVLPDYATSGEPINLVTPSARFVPRRVRLLIDMLTESIRQELE
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
NADPT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]