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The map label for this gene is regX3 [H]

Identifier: 187927526

GI number: 187927526

Start: 455034

End: 455774

Strand: Direct

Name: regX3 [H]

Synonym: Rpic_0424

Alternate gene names: 187927526

Gene position: 455034-455774 (Clockwise)

Preceding gene: 187927525

Following gene: 187927527

Centisome position: 11.54

GC content: 62.08

Gene sequence:

>741_bases
ATGCGTATCGCCTTGCTTGAAGACGATCCCTTCCAAAGCGAAGTCATCGTCCAGATCCTGTCTCAGTCCGGCCACGACGT
GGTGACCTACACCGACGGCTCAACCTTGCTGCGCATGCTGGGCCGGTCGTCGTACGACATGCTGATCCTCGACTGGCATA
CGCCTGGCATGCTCGGTATCGACGTGCTGAGCGTCGTGCGCAGCCGCCACAAGGATGTGTTGCCGGTCCTGTTCGTCACG
GCTGAAGAGGGCGAGAAAAGCCTTGTGCGCGCGCTCACGCATGGCGCCGATGATTACATCGCCAAGCCGTTCCGCATTGC
CGAACTGCGTGCGCGCGTCGACGCGCTGCTGCGCCGCGCATATCCCATTCCGTATGGCCGCCTGCCATTCGCGGTAGGGC
CCTATCACTTCAATCCCCAGCGCCAGCAGGTCACCCTGCACGGCGAGCCGGTTACGCTGACGGGCATCGAGTTCCAGCTG
GCGCTGCTGTTGTTTTCGAACGTGGGCCGCACACTATCGCGCGACCACATCTTCGGGCAGGTGTGGGGCCGCAACTCGTC
GGAGTACACCCGCACGATCGATAGTCACGTATCGCGCATCCGCATGAAGCTGAATGTCGAACCGGTGAACGAGGTGCGCC
TGGTGGCGGTGTACAAGCACGGCTATCGGGTGGACCACCTGAGGCCTGCGGACGACATGAATGCGCTGTCGGACATGGAC
GCTGCGTTCTACAGCACCTAA

Upstream 100 bases:

>100_bases
ACGTAACACATGCAACGGAGCGCGCTGAACGCGCTTGAATAAGCGCCATCAATTCCGGCACCCACCCCCTACGCATGTGC
GAATTTCCATGGAGCCGAAC

Downstream 100 bases:

>100_bases
GCACGGGTGGATCATTCGCACAGAATGGGGCGCCACCGCAGGAATGCGGCGGCGCCGTTTTTGTTGCTCATCGACTGGTA
TGCTCAGGGCTTCTCATATC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRIALLEDDPFQSEVIVQILSQSGHDVVTYTDGSTLLRMLGRSSYDMLILDWHTPGMLGIDVLSVVRSRHKDVLPVLFVT
AEEGEKSLVRALTHGADDYIAKPFRIAELRARVDALLRRAYPIPYGRLPFAVGPYHFNPQRQQVTLHGEPVTLTGIEFQL
ALLLFSNVGRTLSRDHIFGQVWGRNSSEYTRTIDSHVSRIRMKLNVEPVNEVRLVAVYKHGYRVDHLRPADDMNALSDMD
AAFYST

Sequences:

>Translated_246_residues
MRIALLEDDPFQSEVIVQILSQSGHDVVTYTDGSTLLRMLGRSSYDMLILDWHTPGMLGIDVLSVVRSRHKDVLPVLFVT
AEEGEKSLVRALTHGADDYIAKPFRIAELRARVDALLRRAYPIPYGRLPFAVGPYHFNPQRQQVTLHGEPVTLTGIEFQL
ALLLFSNVGRTLSRDHIFGQVWGRNSSEYTRTIDSHVSRIRMKLNVEPVNEVRLVAVYKHGYRVDHLRPADDMNALSDMD
AAFYST
>Mature_246_residues
MRIALLEDDPFQSEVIVQILSQSGHDVVTYTDGSTLLRMLGRSSYDMLILDWHTPGMLGIDVLSVVRSRHKDVLPVLFVT
AEEGEKSLVRALTHGADDYIAKPFRIAELRARVDALLRRAYPIPYGRLPFAVGPYHFNPQRQQVTLHGEPVTLTGIEFQL
ALLLFSNVGRTLSRDHIFGQVWGRNSSEYTRTIDSHVSRIRMKLNVEPVNEVRLVAVYKHGYRVDHLRPADDMNALSDMD
AAFYST

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.7777777777778, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1789402, Length=212, Percent_Identity=36.3207547169811, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=32.4324324324324, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790860, Length=213, Percent_Identity=32.3943661971831, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.9734513274336, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786784, Length=205, Percent_Identity=33.6585365853659, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=35.8851674641148, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.6306306306306, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.1479820627803, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790552, Length=213, Percent_Identity=29.5774647887324, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=28.0701754385965, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=32.2222222222222, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=27.3127753303965, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=24.5689655172414, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=175, Percent_Identity=29.7142857142857, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=28.099173553719, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27887; Mature: 27887

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALLEDDPFQSEVIVQILSQSGHDVVTYTDGSTLLRMLGRSSYDMLILDWHTPGMLGI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCHHH
DVLSVVRSRHKDVLPVLFVTAEEGEKSLVRALTHGADDYIAKPFRIAELRARVDALLRRA
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
YPIPYGRLPFAVGPYHFNPQRQQVTLHGEPVTLTGIEFQLALLLFSNVGRTLSRDHIFGQ
CCCCCCCCCCEECCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCHHHHCCEEEE
VWGRNSSEYTRTIDSHVSRIRMKLNVEPVNEVRLVAVYKHGYRVDHLRPADDMNALSDMD
ECCCCCHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEECCEEECCCCCCHHHHHHHHHH
AAFYST
HHHCCC
>Mature Secondary Structure
MRIALLEDDPFQSEVIVQILSQSGHDVVTYTDGSTLLRMLGRSSYDMLILDWHTPGMLGI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCHHH
DVLSVVRSRHKDVLPVLFVTAEEGEKSLVRALTHGADDYIAKPFRIAELRARVDALLRRA
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
YPIPYGRLPFAVGPYHFNPQRQQVTLHGEPVTLTGIEFQLALLLFSNVGRTLSRDHIFGQ
CCCCCCCCCCEECCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCHHHHCCEEEE
VWGRNSSEYTRTIDSHVSRIRMKLNVEPVNEVRLVAVYKHGYRVDHLRPADDMNALSDMD
ECCCCCHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEECCEEECCCCCCHHHHHHHHHH
AAFYST
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA