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The map label for this gene is corC [H]

Identifier: 187927507

GI number: 187927507

Start: 430261

End: 431190

Strand: Reverse

Name: corC [H]

Synonym: Rpic_0404

Alternate gene names: 187927507

Gene position: 431190-430261 (Counterclockwise)

Preceding gene: 187927508

Following gene: 187927506

Centisome position: 10.94

GC content: 62.47

Gene sequence:

>930_bases
ATGCTGGCCCGATGTTTAACGACGCGCGACCGCGCCATGAATGATCCGTATCCCAGTCCGAAGCCAGCCGACAAACCCCG
TACGCTGCTGGAACGCCTGACCGACCTCATCTCGCCCGAGCCCGAATCGCGGGCCGAGTTGCTCGAAATCCTCCAAGACG
CCCATGCGCGCAGCCTCATCGACGCCGACTCCCTGTCGATGATCGAAGGCGTCTTCCAGGTCTCAGACCTGTGTGCGCGC
GACATCATGATCCCGCGCGCGCAGATGGACGCGCTCAACATCGCCGACGCACCATCAGAATTCATCCCCTTCGTGCAGGA
AGCCGCGCATTCGCGCTTCCCCGTCTACGAAGGCAGTCGCGACAACATCATCGGCATTCTGCTCGCCAAGGATCTGCTGC
GCTTCTATACCGATGAAGACTTCGACGTGCGCGACATGCTGCGCCCGGCCGTATTCATCCCCGAATCCAAGCGACTGAAC
GTGCTGTTGCGAGACTTCCGCGTCAACCGCAACCACATCGCCATCGTCGTTGACGAATACGGCGGCGTGGCAGGCCTCAT
CACCATCGAAGACGTGCTGGAGCAGATCGTCGGCGACATTGAAGACGAATACGACTTCGATCAGGAAGAAGACAACATTC
TGCCGACCGCCGATGGCCACATGCGCGTGCGCGGCCTGACCGAAATCAGCCAGTTCAACGAAGCCTTCGGCACGCATTTC
TCCGACGAAGACGTCGATACCGTGGGCGGGCTGCTGTCCAACCACCTGGGCCGCGTGCCGCACCGGGGCGAAAAGATCGT
CATGGGCACGCTGCAATTCGACGTGCTGCGCGCCGATGCGCGCCAGGTGCAGGTGCTGCTCGTGCGCCGCCTCACCACGC
CGGCCGGCGGCAATGCCACAGCCGACACCTCTGGTTCTCACCCCGCCTGA

Upstream 100 bases:

>100_bases
TCTTAACGCGCCCGAGCCCGGCCTCCAGATGTGAAATAAACCGCACTTCTGGAGACCTAGCAGCCACCCTGCGTCATCGG
GACGGCTGGGCTTTTGGTGT

Downstream 100 bases:

>100_bases
TCCCTCCGTGCCCGCTCAGTTCTCTTCCCCTGCCGCACCATCCCGTCGGCAGGATGCCCAAGCTGTGCCGCTCGCGCGGC
TGCGTTTCGCGATGCCGCTT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MLARCLTTRDRAMNDPYPSPKPADKPRTLLERLTDLISPEPESRAELLEILQDAHARSLIDADSLSMIEGVFQVSDLCAR
DIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSRDNIIGILLAKDLLRFYTDEDFDVRDMLRPAVFIPESKRLN
VLLRDFRVNRNHIAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHF
SDEDVDTVGGLLSNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTTPAGGNATADTSGSHPA

Sequences:

>Translated_309_residues
MLARCLTTRDRAMNDPYPSPKPADKPRTLLERLTDLISPEPESRAELLEILQDAHARSLIDADSLSMIEGVFQVSDLCAR
DIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSRDNIIGILLAKDLLRFYTDEDFDVRDMLRPAVFIPESKRLN
VLLRDFRVNRNHIAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHF
SDEDVDTVGGLLSNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTTPAGGNATADTSGSHPA
>Mature_309_residues
MLARCLTTRDRAMNDPYPSPKPADKPRTLLERLTDLISPEPESRAELLEILQDAHARSLIDADSLSMIEGVFQVSDLCAR
DIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSRDNIIGILLAKDLLRFYTDEDFDVRDMLRPAVFIPESKRLN
VLLRDFRVNRNHIAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHF
SDEDVDTVGGLLSNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTTPAGGNATADTSGSHPA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=32.5358851674641, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI40068053, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40068055, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI94681046, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=48.6166007905138, Blast_Score=210, Evalue=9e-56,
Organism=Escherichia coli, GI145693175, Length=265, Percent_Identity=29.4339622641509, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082033, Length=268, Percent_Identity=26.4925373134328, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=224, Percent_Identity=33.0357142857143, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790664, Length=240, Percent_Identity=25.4166666666667, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34475; Mature: 34475

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARCLTTRDRAMNDPYPSPKPADKPRTLLERLTDLISPEPESRAELLEILQDAHARSLI
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DADSLSMIEGVFQVSDLCARDIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
DNIIGILLAKDLLRFYTDEDFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNHIAIVVDEY
CCEEHHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCHHHHHHHHHCCCCCEEEEEEECC
GGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHF
CCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
SDEDVDTVGGLLSNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTTPAGGNAT
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ADTSGSHPA
CCCCCCCCC
>Mature Secondary Structure
MLARCLTTRDRAMNDPYPSPKPADKPRTLLERLTDLISPEPESRAELLEILQDAHARSLI
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DADSLSMIEGVFQVSDLCARDIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
DNIIGILLAKDLLRFYTDEDFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNHIAIVVDEY
CCEEHHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCHHHHHHHHHCCCCCEEEEEEECC
GGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHF
CCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
SDEDVDTVGGLLSNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTTPAGGNAT
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ADTSGSHPA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]