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The map label for this gene is lnt [H]

Identifier: 187927506

GI number: 187927506

Start: 428685

End: 430196

Strand: Reverse

Name: lnt [H]

Synonym: Rpic_0403

Alternate gene names: 187927506

Gene position: 430196-428685 (Counterclockwise)

Preceding gene: 187927507

Following gene: 187927505

Centisome position: 10.91

GC content: 67.59

Gene sequence:

>1512_bases
GTGCCGCTCGCGCGGCTGCGTTTCGCGATGCCGCTTGCAGCGTTGCTTGGCGTCATGCATACGCTGTCGTTTGCACCGAA
CCACTGGTGGTGGCTGCAGATCCTCTCGCTCACGGGGCTGGCCGCGCTCGTGCAGCGCGCCGCGCGCCTGCGTGAAGCGG
CGTGGGTCGGATATGCGTTCGGGCTCGGCTGGTTCCTGTCGGGCGTCTGGTGGCTCTATATCAGCATGCATGTCTACGGC
GACATGCCGGCGTGGATGGGCGCGCTGGCAGTGCTGCTGTTTGCCGGCTACCTGGCGCTGCATCCGGCGCTGGCGGTGTG
GGCATGGCAGTGGCTGACGAGACGCGGGCGGTGGTCCGGTACCGCATCCGCGCTCATATTTGGCGCGGCATGGGCCGTCA
CGGAATGGCTGCGCGGCACAGTCTGGACGGGCTTCCCCTGGATCAACGGGGGCTACGCGCACACCGATGGCCCGCTGGCC
GGCTACGCGCCGCTGGTGGGCGTCTACGGCATCGTGCTGATCGCCGCCGTGCTGGCTGGCCTGCTGTGCGTCGCGGCCGA
GCGCCGCCTGCATTGGCTGGCGGGCATCGCGGGTGCGCTCGTGCTGGTGGCCGGCTGGCCGCTGCACGGCATTGCGTGGA
CGCAGCCGGTGGGCAAGCCGATCTCCGTGCGTCTCTTGCAGGGCAACGTGCCGCAGGACGTGAAGTTCCAGCAAACCGGC
ATCGAGCGCTCGCTGGAGCTGTACACCAAGATGGTCACCGAGAAGCCCGCGCAACTCGTGGTCACACCCGAGACGGCCTT
CCCGATCATGATTCAGGAGATGCCGCAGGAGATCGCGCTGGCCCTCCGCACCTATGTGGATACCACCGGCTCCAGCGTGC
TGTTCGGCGCCGCCAGCGAGGACTCCCGCGTCGATTACACCAACAGCGTGTTCGGCATCGGCCCGCAATTCCAGGGCGTG
TACCGCTACAACAAGCACCACCTCGTGCCGTTCGGCGAGTTCATCCCCTTCGGTTTCCACTGGTTCGTCAACATGATGAA
CATGCCGCTGGGCGACTTCCGGCGTGGCCTGCCCGTGCAGCCGCCCATGGCGGTGGCCGACCAGCGCGTCGCACCCAACA
TCTGCTACGAAGATTTGTTTGGCGAGGAAATTGCCGCCTCGCTGCGACATGCGGATCAGCCCGCCACGATGCTCGCCAAC
GTGACGAACCTGGCGTGGTTTGGCGACACGATCGCGCTGGACCAGCACCTGCAGATCTCGCGCATGCGCGCGCTGGAAAC
GGGCCGTCCGATGCTGCGCGCCACCAACACGGGGGCGACCGCCGTGGTGCGGCCCGACGGCAGCGTACAGGCCCGTCTAC
CGGTCTTCACGCTTGGCACATTGCAGACTGACGTGCAAGGCACGCAAGGCCTGACGCCATTCGTGCGGACCGGCAACGCG
CCCGCGCTGGGCCTGGGCGCGCTGGTTCTGCTGGTGGCATTCGTGCGCCGCCGCCGGGCTTCGGCAGATTGA

Upstream 100 bases:

>100_bases
GCCACAGCCGACACCTCTGGTTCTCACCCCGCCTGATCCCTCCGTGCCCGCTCAGTTCTCTTCCCCTGCCGCACCATCCC
GTCGGCAGGATGCCCAAGCT

Downstream 100 bases:

>100_bases
TCGTTCAGCGTCCGGAGGGCTTTCGAGCCACTTTCCGGAGTCGCTGACAAAAAACGCTAAAATTCAACGTTTTACGGCGG
GCAGGGAGCCAGGCGCTTCC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MPLARLRFAMPLAALLGVMHTLSFAPNHWWWLQILSLTGLAALVQRAARLREAAWVGYAFGLGWFLSGVWWLYISMHVYG
DMPAWMGALAVLLFAGYLALHPALAVWAWQWLTRRGRWSGTASALIFGAAWAVTEWLRGTVWTGFPWINGGYAHTDGPLA
GYAPLVGVYGIVLIAAVLAGLLCVAAERRLHWLAGIAGALVLVAGWPLHGIAWTQPVGKPISVRLLQGNVPQDVKFQQTG
IERSLELYTKMVTEKPAQLVVTPETAFPIMIQEMPQEIALALRTYVDTTGSSVLFGAASEDSRVDYTNSVFGIGPQFQGV
YRYNKHHLVPFGEFIPFGFHWFVNMMNMPLGDFRRGLPVQPPMAVADQRVAPNICYEDLFGEEIAASLRHADQPATMLAN
VTNLAWFGDTIALDQHLQISRMRALETGRPMLRATNTGATAVVRPDGSVQARLPVFTLGTLQTDVQGTQGLTPFVRTGNA
PALGLGALVLLVAFVRRRRASAD

Sequences:

>Translated_503_residues
MPLARLRFAMPLAALLGVMHTLSFAPNHWWWLQILSLTGLAALVQRAARLREAAWVGYAFGLGWFLSGVWWLYISMHVYG
DMPAWMGALAVLLFAGYLALHPALAVWAWQWLTRRGRWSGTASALIFGAAWAVTEWLRGTVWTGFPWINGGYAHTDGPLA
GYAPLVGVYGIVLIAAVLAGLLCVAAERRLHWLAGIAGALVLVAGWPLHGIAWTQPVGKPISVRLLQGNVPQDVKFQQTG
IERSLELYTKMVTEKPAQLVVTPETAFPIMIQEMPQEIALALRTYVDTTGSSVLFGAASEDSRVDYTNSVFGIGPQFQGV
YRYNKHHLVPFGEFIPFGFHWFVNMMNMPLGDFRRGLPVQPPMAVADQRVAPNICYEDLFGEEIAASLRHADQPATMLAN
VTNLAWFGDTIALDQHLQISRMRALETGRPMLRATNTGATAVVRPDGSVQARLPVFTLGTLQTDVQGTQGLTPFVRTGNA
PALGLGALVLLVAFVRRRRASAD
>Mature_502_residues
PLARLRFAMPLAALLGVMHTLSFAPNHWWWLQILSLTGLAALVQRAARLREAAWVGYAFGLGWFLSGVWWLYISMHVYGD
MPAWMGALAVLLFAGYLALHPALAVWAWQWLTRRGRWSGTASALIFGAAWAVTEWLRGTVWTGFPWINGGYAHTDGPLAG
YAPLVGVYGIVLIAAVLAGLLCVAAERRLHWLAGIAGALVLVAGWPLHGIAWTQPVGKPISVRLLQGNVPQDVKFQQTGI
ERSLELYTKMVTEKPAQLVVTPETAFPIMIQEMPQEIALALRTYVDTTGSSVLFGAASEDSRVDYTNSVFGIGPQFQGVY
RYNKHHLVPFGEFIPFGFHWFVNMMNMPLGDFRRGLPVQPPMAVADQRVAPNICYEDLFGEEIAASLRHADQPATMLANV
TNLAWFGDTIALDQHLQISRMRALETGRPMLRATNTGATAVVRPDGSVQARLPVFTLGTLQTDVQGTQGLTPFVRTGNAP
ALGLGALVLLVAFVRRRRASAD

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=515, Percent_Identity=36.504854368932, Blast_Score=292, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 55149; Mature: 55018

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLARLRFAMPLAALLGVMHTLSFAPNHWWWLQILSLTGLAALVQRAARLREAAWVGYAF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGWFLSGVWWLYISMHVYGDMPAWMGALAVLLFAGYLALHPALAVWAWQWLTRRGRWSG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TASALIFGAAWAVTEWLRGTVWTGFPWINGGYAHTDGPLAGYAPLVGVYGIVLIAAVLAG
CHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLCVAAERRLHWLAGIAGALVLVAGWPLHGIAWTQPVGKPISVRLLQGNVPQDVKFQQTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEECCCCCCCCHHHHH
IERSLELYTKMVTEKPAQLVVTPETAFPIMIQEMPQEIALALRTYVDTTGSSVLFGAASE
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DSRVDYTNSVFGIGPQFQGVYRYNKHHLVPFGEFIPFGFHWFVNMMNMPLGDFRRGLPVQ
CCCCCCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
PPMAVADQRVAPNICYEDLFGEEIAASLRHADQPATMLANVTNLAWFGDTIALDQHLQIS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCHHHHH
RMRALETGRPMLRATNTGATAVVRPDGSVQARLPVFTLGTLQTDVQGTQGLTPFVRTGNA
HHHHHHCCCCCEEECCCCCEEEECCCCCCEEECCEEEECCHHHCCCCCCCCCHHHCCCCC
PALGLGALVLLVAFVRRRRASAD
CCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLARLRFAMPLAALLGVMHTLSFAPNHWWWLQILSLTGLAALVQRAARLREAAWVGYAF
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGWFLSGVWWLYISMHVYGDMPAWMGALAVLLFAGYLALHPALAVWAWQWLTRRGRWSG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TASALIFGAAWAVTEWLRGTVWTGFPWINGGYAHTDGPLAGYAPLVGVYGIVLIAAVLAG
CHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLCVAAERRLHWLAGIAGALVLVAGWPLHGIAWTQPVGKPISVRLLQGNVPQDVKFQQTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEECCCCCCCCHHHHH
IERSLELYTKMVTEKPAQLVVTPETAFPIMIQEMPQEIALALRTYVDTTGSSVLFGAASE
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DSRVDYTNSVFGIGPQFQGVYRYNKHHLVPFGEFIPFGFHWFVNMMNMPLGDFRRGLPVQ
CCCCCCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
PPMAVADQRVAPNICYEDLFGEEIAASLRHADQPATMLANVTNLAWFGDTIALDQHLQIS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCHHHHH
RMRALETGRPMLRATNTGATAVVRPDGSVQARLPVFTLGTLQTDVQGTQGLTPFVRTGNA
HHHHHHCCCCCEEECCCCCEEEECCCCCCEEECCEEEECCHHHCCCCCCCCCHHHCCCCC
PALGLGALVLLVAFVRRRRASAD
CCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]