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The map label for this gene is resD [H]

Identifier: 187927399

GI number: 187927399

Start: 313383

End: 314111

Strand: Reverse

Name: resD [H]

Synonym: Rpic_0295

Alternate gene names: 187927399

Gene position: 314111-313383 (Counterclockwise)

Preceding gene: 187927404

Following gene: 187927398

Centisome position: 7.97

GC content: 63.24

Gene sequence:

>729_bases
ATGGACTCTGCCAAACGCGTCCTGCTCGTTGAAGATGACGCACACATCGCGGAATTGCTGCGCATGCACCTCCGGGACGA
GGGTTATGCGGTGGTGCACGCGGCTGACGGCCATGCGGGCCAGCGGGAAATGGAACGGGGCAACTGGGATGCGCTGGTGC
TCGACCTGATGCTGCCTGGCATCGACGGCCTGGAGATTTGCCGCCGCGCGCGGGTGCAGGCCCGCTACACGCCAATCATC
ATCATCAGTGCCCGGTCGACCGAGGTGCACCGCATCTTGGGGCTGGAGCTCGGCGCAGACGACTACCTTGCCAAGCCCTT
CTCGGTGTTGGAGCTGGTGGCGCGCGTGAAGGCACTGATTCGACGTACCGACGCGCTGGCGCGTAACGCGCGCATGGAGT
CGGGTAGCCTCACACTAGGCAATCTTGAGATCGAACCACTAGCGCGCGAGGTGCGCGTCGACGGCAAACCGATCGAACTC
ACGCCGCGCGAGTTCGACCTACTTCATTTCTTCGCACGTCATCCGGGCAAAGTGTTTTCGAGGCTCGACCTGCTCAATCA
AGTCTGGGGCTACCAGCACGACGGCTACGAGCATACGGTTAACACTCACATCAACCGGCTGCGAGCCAAGGTCGAGGTCG
ACCCGGCGCAGCCGCGGCGCATACTCACCGTCTGGGGGCGCGGCTACAAGCTCTCTATCGGGGCAGACGGCAAGGAGGAC
GCAGCATGA

Upstream 100 bases:

>100_bases
TTCATCACGCAAAGTTCAATTAATTGTGATAACTGCGCCGGTCAGATCGCGGGACAATCAGTCCTAAAGAACGCTTTAGA
CATCCCTTTCCCCACGCCCC

Downstream 100 bases:

>100_bases
GTGGACGAGGGGAGGCAGTGCTATCTCGACGGCTCTCGCTGGTATTCGCTGTGCTGTTGCTGGTGTGCTGCGGCACTTCG
GCTTGGCTGCAATTGCGCTC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MDSAKRVLLVEDDAHIAELLRMHLRDEGYAVVHAADGHAGQREMERGNWDALVLDLMLPGIDGLEICRRARVQARYTPII
IISARSTEVHRILGLELGADDYLAKPFSVLELVARVKALIRRTDALARNARMESGSLTLGNLEIEPLAREVRVDGKPIEL
TPREFDLLHFFARHPGKVFSRLDLLNQVWGYQHDGYEHTVNTHINRLRAKVEVDPAQPRRILTVWGRGYKLSIGADGKED
AA

Sequences:

>Translated_242_residues
MDSAKRVLLVEDDAHIAELLRMHLRDEGYAVVHAADGHAGQREMERGNWDALVLDLMLPGIDGLEICRRARVQARYTPII
IISARSTEVHRILGLELGADDYLAKPFSVLELVARVKALIRRTDALARNARMESGSLTLGNLEIEPLAREVRVDGKPIEL
TPREFDLLHFFARHPGKVFSRLDLLNQVWGYQHDGYEHTVNTHINRLRAKVEVDPAQPRRILTVWGRGYKLSIGADGKED
AA
>Mature_242_residues
MDSAKRVLLVEDDAHIAELLRMHLRDEGYAVVHAADGHAGQREMERGNWDALVLDLMLPGIDGLEICRRARVQARYTPII
IISARSTEVHRILGLELGADDYLAKPFSVLELVARVKALIRRTDALARNARMESGSLTLGNLEIEPLAREVRVDGKPIEL
TPREFDLLHFFARHPGKVFSRLDLLNQVWGYQHDGYEHTVNTHINRLRAKVEVDPAQPRRILTVWGRGYKLSIGADGKED
AA

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=40.4347826086956, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=39.3939393939394, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=36.5638766519824, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=39.1111111111111, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=35.8407079646018, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=37.6623376623377, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=37.0044052863436, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=38.3259911894273, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=37.8854625550661, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=33.1877729257642, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=33.4782608695652, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.0357142857143, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=35.2173913043478, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27290; Mature: 27290

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSAKRVLLVEDDAHIAELLRMHLRDEGYAVVHAADGHAGQREMERGNWDALVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCHHEEEEEHHCCC
IDGLEICRRARVQARYTPIIIISARSTEVHRILGLELGADDYLAKPFSVLELVARVKALI
CCHHHHHHHHHCCEECCCEEEEEECCCCEEHEEEEEECCCHHHHCHHHHHHHHHHHHHHH
RRTDALARNARMESGSLTLGNLEIEPLAREVRVDGKPIELTPREFDLLHFFARHPGKVFS
HHHHHHHHHCCCCCCCEEECCEECCCHHHHHCCCCCCEEECCCHHHHHHHHHHCCHHHHH
RLDLLNQVWGYQHDGYEHTVNTHINRLRAKVEVDPAQPRRILTVWGRGYKLSIGADGKED
HHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCEEEEEECCCEEEEECCCCCCC
AA
CC
>Mature Secondary Structure
MDSAKRVLLVEDDAHIAELLRMHLRDEGYAVVHAADGHAGQREMERGNWDALVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCHHEEEEEHHCCC
IDGLEICRRARVQARYTPIIIISARSTEVHRILGLELGADDYLAKPFSVLELVARVKALI
CCHHHHHHHHHCCEECCCEEEEEECCCCEEHEEEEEECCCHHHHCHHHHHHHHHHHHHHH
RRTDALARNARMESGSLTLGNLEIEPLAREVRVDGKPIELTPREFDLLHFFARHPGKVFS
HHHHHHHHHCCCCCCCEEECCEECCCHHHHHCCCCCCEEECCCHHHHHHHHHHCCHHHHH
RLDLLNQVWGYQHDGYEHTVNTHINRLRAKVEVDPAQPRRILTVWGRGYKLSIGADGKED
HHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCEEEEEECCCEEEEECCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]