Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 187927398

GI number: 187927398

Start: 311890

End: 313386

Strand: Reverse

Name: resE [H]

Synonym: Rpic_0294

Alternate gene names: 187927398

Gene position: 313386-311890 (Counterclockwise)

Preceding gene: 187927399

Following gene: 187927390

Centisome position: 7.95

GC content: 62.53

Gene sequence:

>1497_bases
ATGAGTGGACGAGGGGAGGCAGTGCTATCTCGACGGCTCTCGCTGGTATTCGCTGTGCTGTTGCTGGTGTGCTGCGGCAC
TTCGGCTTGGCTGCAATTGCGCTCGAACGGACGTCACGAGCAGGAGGTGATCCAACGCTTGTCGAGCGGGTTGGCCGCAC
ACATCGCGGAGAATGCCGAACTGATGCGACCGGAAGGACTAAACCCTGTCGCGGTGAAAGATCTGTTCGACAAACTGATG
GCGGTGAATCCTAGCGTAGAGGTCTACCTGCTCTCGCCTGACGGCCACATTGCGGCGCAAGCGGCGCCCCCCGGCCACCT
CAAGCGCGACCGCGTCGACCTCGCACCGGTGCGCAGACTGCTCGCTGGTGCGACGATGCCGGTCCTCGGTGACGATCCAC
GCAACTTGCAAACGCCCAAAGTTTTTAGCGCCGCGCCGATGCGCGTTGATGGCCGAGACGCAGGTTACGTCTACGTGGTG
CTGCAGGGCGAGGACCACGACGCCGTTGCCGCGCACGTGGCGGCTGACAACGTTTTGCGGACAACGCTGTGGTCCATGGG
GCTGGTGGCTCTTCTCGGGCTTGTAGCGGGCACGGTGGCGTTCTGGCTCATCACGCGGCCTCTGCGCGAGCTGACGGCTG
TAGTCCGACGCTTCGAATCCGAAGGAATCGGATCGCTCGAAAGCCAAACGGCGACGCTGGAGCGCATTGCGCGCGGTGGC
GGAGAAATAGCGACACTGAGCCAGGCCTTCGTGCAGATGACGCGGCGCATTGCTGAGCAGTGGCGAGAGCTGACGCTGCA
GGACCAGCAGCGCCGCGAACTCGTCGCCAATATCTCGCATGACCTGCGCACGCCCCTGACTTCACTACACGGCTACCTGG
AAACGCTCCGACTGAAGGCCGGTATCCTCGACGACGAAGAGCGCCGCCGCTACCTCGACATTGCGCTCGGTCAGAGCCGC
AAGGTTGGCCGGCTCGCACAGGAGCTATTTGAGCTAGCACGGCTTGAGTACGGCGTGGTTAAGCCAGAAAAGGAAAATTT
CGCGTTGGCCGACCTGGTACAAGACGTGTTTCAGAAGTTCGAGTTGGCAGCAGGGGCGCGTCAGCAACAACTCAAGCCAG
ACATTGCGCCCGGTCTGCCCATCGTGTCGGCCGACTTGGGCATGATCGAGCGCGTGTTAACAAACCTGCTCGACAACGCC
ATCCACCATACGCCAGTAGGCGGCGCGATCGAGGTGCAGTTGCGTCCAACGAATACTGGGGTCGCGGTCCAGGTTAGCGA
CACCGGGCCGGGTATCCCAGGTGAACTTCAGAAGGGACTCTTCGTGCGTCCAGTGTTCATGAGCGGTGCCCGCAGCGATG
GCTCACGCAGCGGTGGGCTCGGGCTGATGATCGTGCAGCGAATCCTGCAGCTGCATGGCAGCGAAATCCGGCTGGTGCCG
CAGCCCGGAAAGGGTGCGGTGTTTTGCTTCCAGTTGGCGGGTGCCGCCAGTGGGTGA

Upstream 100 bases:

>100_bases
CCAAGGTCGAGGTCGACCCGGCGCAGCCGCGGCGCATACTCACCGTCTGGGGGCGCGGCTACAAGCTCTCTATCGGGGCA
GACGGCAAGGAGGACGCAGC

Downstream 100 bases:

>100_bases
TGTTGACCGCTATTGCGTGAGCCTGACCAAGGCTTGCGCGTTGTTCCACATGTCATGCTCGCTATACGCGTATCGGTCGG
TTGCTCGCGACTCGTCGGCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSGRGEAVLSRRLSLVFAVLLLVCCGTSAWLQLRSNGRHEQEVIQRLSSGLAAHIAENAELMRPEGLNPVAVKDLFDKLM
AVNPSVEVYLLSPDGHIAAQAAPPGHLKRDRVDLAPVRRLLAGATMPVLGDDPRNLQTPKVFSAAPMRVDGRDAGYVYVV
LQGEDHDAVAAHVAADNVLRTTLWSMGLVALLGLVAGTVAFWLITRPLRELTAVVRRFESEGIGSLESQTATLERIARGG
GEIATLSQAFVQMTRRIAEQWRELTLQDQQRRELVANISHDLRTPLTSLHGYLETLRLKAGILDDEERRRYLDIALGQSR
KVGRLAQELFELARLEYGVVKPEKENFALADLVQDVFQKFELAAGARQQQLKPDIAPGLPIVSADLGMIERVLTNLLDNA
IHHTPVGGAIEVQLRPTNTGVAVQVSDTGPGIPGELQKGLFVRPVFMSGARSDGSRSGGLGLMIVQRILQLHGSEIRLVP
QPGKGAVFCFQLAGAASG

Sequences:

>Translated_498_residues
MSGRGEAVLSRRLSLVFAVLLLVCCGTSAWLQLRSNGRHEQEVIQRLSSGLAAHIAENAELMRPEGLNPVAVKDLFDKLM
AVNPSVEVYLLSPDGHIAAQAAPPGHLKRDRVDLAPVRRLLAGATMPVLGDDPRNLQTPKVFSAAPMRVDGRDAGYVYVV
LQGEDHDAVAAHVAADNVLRTTLWSMGLVALLGLVAGTVAFWLITRPLRELTAVVRRFESEGIGSLESQTATLERIARGG
GEIATLSQAFVQMTRRIAEQWRELTLQDQQRRELVANISHDLRTPLTSLHGYLETLRLKAGILDDEERRRYLDIALGQSR
KVGRLAQELFELARLEYGVVKPEKENFALADLVQDVFQKFELAAGARQQQLKPDIAPGLPIVSADLGMIERVLTNLLDNA
IHHTPVGGAIEVQLRPTNTGVAVQVSDTGPGIPGELQKGLFVRPVFMSGARSDGSRSGGLGLMIVQRILQLHGSEIRLVP
QPGKGAVFCFQLAGAASG
>Mature_497_residues
SGRGEAVLSRRLSLVFAVLLLVCCGTSAWLQLRSNGRHEQEVIQRLSSGLAAHIAENAELMRPEGLNPVAVKDLFDKLMA
VNPSVEVYLLSPDGHIAAQAAPPGHLKRDRVDLAPVRRLLAGATMPVLGDDPRNLQTPKVFSAAPMRVDGRDAGYVYVVL
QGEDHDAVAAHVAADNVLRTTLWSMGLVALLGLVAGTVAFWLITRPLRELTAVVRRFESEGIGSLESQTATLERIARGGG
EIATLSQAFVQMTRRIAEQWRELTLQDQQRRELVANISHDLRTPLTSLHGYLETLRLKAGILDDEERRRYLDIALGQSRK
VGRLAQELFELARLEYGVVKPEKENFALADLVQDVFQKFELAAGARQQQLKPDIAPGLPIVSADLGMIERVLTNLLDNAI
HHTPVGGAIEVQLRPTNTGVAVQVSDTGPGIPGELQKGLFVRPVFMSGARSDGSRSGGLGLMIVQRILQLHGSEIRLVPQ
PGKGAVFCFQLAGAASG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=29.1512915129151, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=31.3636363636364, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=352, Percent_Identity=27.8409090909091, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.5833333333333, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=29.1304347826087, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=345, Percent_Identity=24.9275362318841, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=25.7839721254355, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=25.8771929824561, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=316, Percent_Identity=24.6835443037975, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=25.5060728744939, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=28.6713286713287, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=340, Percent_Identity=27.6470588235294, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=24.8908296943231, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=26.6968325791855, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787894, Length=314, Percent_Identity=26.7515923566879, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54023; Mature: 53892

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRGEAVLSRRLSLVFAVLLLVCCGTSAWLQLRSNGRHEQEVIQRLSSGLAAHIAENAE
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
LMRPEGLNPVAVKDLFDKLMAVNPSVEVYLLSPDGHIAAQAAPPGHLKRDRVDLAPVRRL
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
LAGATMPVLGDDPRNLQTPKVFSAAPMRVDGRDAGYVYVVLQGEDHDAVAAHVAADNVLR
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
TTLWSMGLVALLGLVAGTVAFWLITRPLRELTAVVRRFESEGIGSLESQTATLERIARGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GEIATLSQAFVQMTRRIAEQWRELTLQDQQRRELVANISHDLRTPLTSLHGYLETLRLKA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILDDEERRRYLDIALGQSRKVGRLAQELFELARLEYGVVKPEKENFALADLVQDVFQKF
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ELAAGARQQQLKPDIAPGLPIVSADLGMIERVLTNLLDNAIHHTPVGGAIEVQLRPTNTG
HHHCCCHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
VAVQVSDTGPGIPGELQKGLFVRPVFMSGARSDGSRSGGLGLMIVQRILQLHGSEIRLVP
EEEEECCCCCCCCHHHHCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
QPGKGAVFCFQLAGAASG
CCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SGRGEAVLSRRLSLVFAVLLLVCCGTSAWLQLRSNGRHEQEVIQRLSSGLAAHIAENAE
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
LMRPEGLNPVAVKDLFDKLMAVNPSVEVYLLSPDGHIAAQAAPPGHLKRDRVDLAPVRRL
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
LAGATMPVLGDDPRNLQTPKVFSAAPMRVDGRDAGYVYVVLQGEDHDAVAAHVAADNVLR
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
TTLWSMGLVALLGLVAGTVAFWLITRPLRELTAVVRRFESEGIGSLESQTATLERIARGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GEIATLSQAFVQMTRRIAEQWRELTLQDQQRRELVANISHDLRTPLTSLHGYLETLRLKA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILDDEERRRYLDIALGQSRKVGRLAQELFELARLEYGVVKPEKENFALADLVQDVFQKF
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ELAAGARQQQLKPDIAPGLPIVSADLGMIERVLTNLLDNAIHHTPVGGAIEVQLRPTNTG
HHHCCCHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
VAVQVSDTGPGIPGELQKGLFVRPVFMSGARSDGSRSGGLGLMIVQRILQLHGSEIRLVP
EEEEECCCCCCCCHHHHCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
QPGKGAVFCFQLAGAASG
CCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]