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The map label for this gene is leuE [H]

Identifier: 187927380

GI number: 187927380

Start: 287198

End: 287815

Strand: Direct

Name: leuE [H]

Synonym: Rpic_0273

Alternate gene names: 187927380

Gene position: 287198-287815 (Clockwise)

Preceding gene: 187927379

Following gene: 187927383

Centisome position: 7.28

GC content: 66.83

Gene sequence:

>618_bases
ATGCCTCACGTATGGCTGTTCCTGCTGACCTCGATTGCGATCACGGTGATGCCCGGGCCGGACAATTTGCAGGTGATTGC
ACGCGGCGCGAGCCAAGGCCGCAAGGCTGGGCTGACGGCGGCGGCGGGATTTGCGTCGGGCTGCCTGTTTCATACGACGC
TGGCCGCACTCGGGCTGGCTGCGGTGCTGCAATCGTCGCCCGTGGCGTTCCAGGCGATCCGGTGGCTGGGCGCGGCGTAT
CTCATCTGGCTGGGCATCCAGGCGCTGCGCAGCAAGGGCGGCGGCCTGGGTCATGCTGGACCGCAGGCGGCCCCGGGCCT
CTGGCAGGTGTATCGCCAGAGTGTCTTTGCGAATCTGCTCAATCCGAAGGTGACGCTGTTCTTCGTGGTGTTCCTGCCGC
AGTTCGTCGATGCGCAGGCCGGCCATGCGGCGCTGCGAATGCTGCTGCTGGGCGGCGTGTTCATGGCGCAGACCATCGTG
GTGTTCAGCGCGTACGGCTGGTGCGCGGCGGCGCTGGGCGGCTGGATGCGCCGTACGCCGCGCGCATCGCTGTGGCTCGA
TCGCTTGAGCGGTTGCATCTTCATCGGGTTGGGCTTGCGCGTGGCCCTGACCAAATAA

Upstream 100 bases:

>100_bases
TGCGCTAGCCGCATACGCTCATGTGACAAAAATATGACGACTTGCTGCTGCGCGCAGTAGCATGACCCCTTCCATTTCCG
CGGCACCCTGGGAGACGTCG

Downstream 100 bases:

>100_bases
GCAAACGCCCGGATCCCCCGGGCGTTTGACTTAGAGCTTGTAGCCGATCTGCCGCAGCAGGTCCTTGCGCCAAGCGATGT
CGGCATCGGTTTCGACACCC

Product: Lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MPHVWLFLLTSIAITVMPGPDNLQVIARGASQGRKAGLTAAAGFASGCLFHTTLAALGLAAVLQSSPVAFQAIRWLGAAY
LIWLGIQALRSKGGGLGHAGPQAAPGLWQVYRQSVFANLLNPKVTLFFVVFLPQFVDAQAGHAALRMLLLGGVFMAQTIV
VFSAYGWCAAALGGWMRRTPRASLWLDRLSGCIFIGLGLRVALTK

Sequences:

>Translated_205_residues
MPHVWLFLLTSIAITVMPGPDNLQVIARGASQGRKAGLTAAAGFASGCLFHTTLAALGLAAVLQSSPVAFQAIRWLGAAY
LIWLGIQALRSKGGGLGHAGPQAAPGLWQVYRQSVFANLLNPKVTLFFVVFLPQFVDAQAGHAALRMLLLGGVFMAQTIV
VFSAYGWCAAALGGWMRRTPRASLWLDRLSGCIFIGLGLRVALTK
>Mature_204_residues
PHVWLFLLTSIAITVMPGPDNLQVIARGASQGRKAGLTAAAGFASGCLFHTTLAALGLAAVLQSSPVAFQAIRWLGAAYL
IWLGIQALRSKGGGLGHAGPQAAPGLWQVYRQSVFANLLNPKVTLFFVVFLPQFVDAQAGHAALRMLLLGGVFMAQTIVV
FSAYGWCAAALGGWMRRTPRASLWLDRLSGCIFIGLGLRVALTK

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=200, Percent_Identity=28.5, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994979, Length=192, Percent_Identity=29.1666666666667, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21731; Mature: 21600

Theoretical pI: Translated: 11.70; Mature: 11.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVWLFLLTSIAITVMPGPDNLQVIARGASQGRKAGLTAAAGFASGCLFHTTLAALGLA
CCHHHHHHHHHHHEEECCCCCCHHEEECCHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVLQSSPVAFQAIRWLGAAYLIWLGIQALRSKGGGLGHAGPQAAPGLWQVYRQSVFANLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NPKVTLFFVVFLPQFVDAQAGHAALRMLLLGGVFMAQTIVVFSAYGWCAAALGGWMRRTP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RASLWLDRLSGCIFIGLGLRVALTK
CHHHHHHHHCCCEEEECCCEEEECC
>Mature Secondary Structure 
PHVWLFLLTSIAITVMPGPDNLQVIARGASQGRKAGLTAAAGFASGCLFHTTLAALGLA
CHHHHHHHHHHHEEECCCCCCHHEEECCHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVLQSSPVAFQAIRWLGAAYLIWLGIQALRSKGGGLGHAGPQAAPGLWQVYRQSVFANLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NPKVTLFFVVFLPQFVDAQAGHAALRMLLLGGVFMAQTIVVFSAYGWCAAALGGWMRRTP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RASLWLDRLSGCIFIGLGLRVALTK
CHHHHHHHHCCCEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA