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The map label for this gene is ycgM [C]

Identifier: 187927346

GI number: 187927346

Start: 254508

End: 255209

Strand: Direct

Name: ycgM [C]

Synonym: Rpic_0239

Alternate gene names: 187927346

Gene position: 254508-255209 (Clockwise)

Preceding gene: 187927340

Following gene: 187927347

Centisome position: 6.46

GC content: 66.95

Gene sequence:

>702_bases
ATGACCGATTTCGTCGTCACCCCGCCCGCCGTCAATGGCATTCCCGTGCGTGGCGGGCATGGCCAGTTTCCGGTGCGCCG
TGTGTACTGCGTCGGCCGCAACTACGCCGCCCATGCGCGCGAGATGGGTTCCGACCCCGACCGCGAACCGCCGTTCTTCT
TCTGCAAGCCGGCCGACGCTGTGCGCTACGTTGCCGACGGCGAGACCGGCCAGTTCGTCTACCCGACTGAAACCAAGGAT
TGCCACTACGAGATCGAACTCGTGGTTGCCATCGGCACGGGCGGGCGCGACATCGCCGTGGAAACGGCAGCCCACCATGT
CTACGGTTACGCCATCGGCCTGGACATGACGCGCCGCGACCTGCAGAACGCTGCCAAGAAGGGCGGCCGCCCGTGGGAGA
CCGGCAAGGCGTTCGACGGCTCGGCCCCCATCGGCCCGATCGTGCCGGCCAAGGATGTGGCCCACCCGGACAAGGGCGCC
GTGACGCTGTCGGTCAACGGCCGCGAACACCAGCGCGGTGATCTGTCGGACCTGATCTGGTCGGTGCCGGAAACCATTGC
GTATCTGTCGCGCCTGTTCGAGCTGCGCCCGGGCGATCTGATCTACACCGGCACGCCCGAAGGCGTCGGCCCGGTCGTCG
TCGGCGACCTGATGGTCGGCAAGATCGACGGCGTGGGAGAGCTGCACGTGAAGGTGATTTGA

Upstream 100 bases:

>100_bases
GGGGCGGTGCGGGTGTATCCTCGCAAACTCGTCGGTCGCCGGGGGGCGGTGGCCGCAGTTTCCCACCTGTTCCAATCCAG
CTTAGTCCGAGGAGACCCGC

Downstream 100 bases:

>100_bases
TAGACCCGCTAGAAGAGTCAGAAGCCATGTCGATCAAGCTGTACAACTATTTCCGCAGTTCGGCGTCATTCCGCGTGCGT
ATTGCCCTGGAGGTCAAGGG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTDFVVTPPAVNGIPVRGGHGQFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPADAVRYVADGETGQFVYPTETKD
CHYEIELVVAIGTGGRDIAVETAAHHVYGYAIGLDMTRRDLQNAAKKGGRPWETGKAFDGSAPIGPIVPAKDVAHPDKGA
VTLSVNGREHQRGDLSDLIWSVPETIAYLSRLFELRPGDLIYTGTPEGVGPVVVGDLMVGKIDGVGELHVKVI

Sequences:

>Translated_233_residues
MTDFVVTPPAVNGIPVRGGHGQFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPADAVRYVADGETGQFVYPTETKD
CHYEIELVVAIGTGGRDIAVETAAHHVYGYAIGLDMTRRDLQNAAKKGGRPWETGKAFDGSAPIGPIVPAKDVAHPDKGA
VTLSVNGREHQRGDLSDLIWSVPETIAYLSRLFELRPGDLIYTGTPEGVGPVVVGDLMVGKIDGVGELHVKVI
>Mature_232_residues
TDFVVTPPAVNGIPVRGGHGQFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPADAVRYVADGETGQFVYPTETKDC
HYEIELVVAIGTGGRDIAVETAAHHVYGYAIGLDMTRRDLQNAAKKGGRPWETGKAFDGSAPIGPIVPAKDVAHPDKGAV
TLSVNGREHQRGDLSDLIWSVPETIAYLSRLFELRPGDLIYTGTPEGVGPVVVGDLMVGKIDGVGELHVKVI

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=41.0628019323672, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=41.5, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=41.5, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI156231349, Length=256, Percent_Identity=31.640625, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI40786394, Length=256, Percent_Identity=30.859375, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1787428, Length=209, Percent_Identity=39.7129186602871, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=36.4583333333333, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=219, Percent_Identity=30.1369863013699, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=32.5358851674641, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=32.8703703703704, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24663695, Length=214, Percent_Identity=28.0373831775701, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25122; Mature: 24991

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFVVTPPAVNGIPVRGGHGQFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPADA
CCCEEECCCCCCCEECCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VRYVADGETGQFVYPTETKDCHYEIELVVAIGTGGRDIAVETAAHHVYGYAIGLDMTRRD
EEEEECCCCCCEEECCCCCCCEEEEEEEEEECCCCCEEEEEHHHHEEEEEEEECCHHHHH
LQNAAKKGGRPWETGKAFDGSAPIGPIVPAKDVAHPDKGAVTLSVNGREHQRGDLSDLIW
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHH
SVPETIAYLSRLFELRPGDLIYTGTPEGVGPVVVGDLMVGKIDGVGELHVKVI
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure 
TDFVVTPPAVNGIPVRGGHGQFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPADA
CCEEECCCCCCCEECCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VRYVADGETGQFVYPTETKDCHYEIELVVAIGTGGRDIAVETAAHHVYGYAIGLDMTRRD
EEEEECCCCCCEEECCCCCCCEEEEEEEEEECCCCCEEEEEHHHHEEEEEEEECCHHHHH
LQNAAKKGGRPWETGKAFDGSAPIGPIVPAKDVAHPDKGAVTLSVNGREHQRGDLSDLIW
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHH
SVPETIAYLSRLFELRPGDLIYTGTPEGVGPVVVGDLMVGKIDGVGELHVKVI
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]